T Cell News and Research

Latest T Cell News and Research

First cell-based gene therapy approved by the FDA for treating multiple myeloma

The U.S. Food and Drug Administration approved Abecma (idecabtagene vicleucel), a cell-based gene therapy to treat adult patients with multiple myeloma who have not responded to, or whose disease has returned after, at least four prior lines (different types) of therapy.

29 Mar 2021

Linear epitope mapping of the SARS-CoV-2 spike protein

The spike protein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been the primary target of many drug discovery efforts and is similarly utilized in each of the approved COVID-19 vaccines to elicit the generation of anti-spike protein antibodies, thereby granting immunity.

28 Mar 2021

Antibody agents effective at neutralizing European, South African, and United States SARS-CoV-2 variants

Researchers in the United States have demonstrated the effectiveness of three antibody agents at neutralizing recently emerged variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent responsible for the coronavirus disease 2019 (COVID-19) pandemic.

28 Mar 2021

New SARS-CoV-2 genome variants identified in US mink

Researchers in Canada have discovered two novel variants in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) gene sequences collected from mink in the United States.

28 Mar 2021

Selecting SARS-CoV-2 inhibitors in human airway epithelial cells

In a recent article currently available on the bioRxiv* preprint server, researchers from Belgium and the U.S. demonstrated a robust replication model for the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) isolates in primary human epithelial cells at the air-liquid interface and appraised the antiviral effect of selected viral replication inhibitors.

28 Mar 2021

Mimicking stress signals can protect the brain and retina from aging

How do different parts of the body communicate? Scientists at St. Jude are studying how signals sent from skeletal muscle affect the brain.

27 Mar 2021

Researchers identify new targets for minimizing tooth sensitivity to cold

Researchers report in Science Advances that they have uncovered a new function for odontoblasts, the cells that form dentin, the shell beneath the tooth's enamel that encases the soft dental pulp containing nerves and blood vessels.

27 Mar 2021

UVA scientists identify a potential way to prevent heart attacks and strokes

Scientists at the University of Virginia School of Medicine have identified a potential way to head off heart attacks and strokes by strengthening the fibrous caps overlying atherosclerotic plaques that naturally accumulate inside our arteries.

27 Mar 2021

Researchers identify new drug candidates for treating patients with severe COVID-19

University of Maryland School of Medicine (UMSOM) researchers have identified the most toxic proteins made by SARS-COV-2--the virus that causes COVID-19 - and then used an FDA-approved cancer drug to blunt the viral protein's detrimental effects.

27 Mar 2021

FDA acknowledged receipt of ORNL’s cancer-fighting Ac-225 isotope

A rare isotope in high demand for treating cancer is now more available to pharmaceutical companies developing and testing new drugs.

27 Mar 2021

Novel molecule could offer a new way to fight against SARS coronavirus 2

Scientists at the University of Bonn and the caesar research center have isolated a molecule that might open new avenues in the fight against SARS coronavirus 2. The active ingredient binds to the spike protein that the virus uses to dock to the cells it infects.

27 Mar 2021

Using molecular ‘cookie cutters’ to isolate first ever COVID-19 encounter complex

University of Birmingham researchers are working to isolate and extract the COVID-19 encounter complex in a form that is stable enough for identification of target sites for future anti-viral drugs.

27 Mar 2021

Heidelberg researchers introduce a reproducible division mechanism for synthetic vesicles

One big challenge for the production of synthetic cells is that they must be able to divide to have offspring. In the journal Angewandte Chemie, a team from Heidelberg has now introduced a reproducible division mechanism for synthetic vesicles.

27 Mar 2021

Stem cell depletion could be an important factor behind miscarriage

Depletion of a certain type of stem cell in the womb lining during pregnancy could be a significant factor behind miscarriage, according to a study released today in STEM CELLS.

27 Mar 2021

New study uncovers potential therapeutic target for lupus

A recent study published in JCI found that a neutrophil's endoplasmic reticulum, the organelle that normally makes proteins in the cell, becomes stressed in the autoimmune disorder lupus.

26 Mar 2021

New blood test makes it easier to follow the progression of multiple myeloma

A new method makes it much easier to follow the progression of multiple myeloma, a form of blood cancer.

26 Mar 2021

Research sheds light on a new neuroprotective mechanism to control damage following brain injury

When the brain suffers injury or infection, glial cells surrounding the affected site act to preserve the brain's sensitive nerve cells and prevent excessive damage.

26 Mar 2021

POSTECH researchers produce artificial lung model using 3D printing

The warmer temperature and blooming flowers signal the arrival of spring. However, worries about respiratory diseases are also on the rise due to fine dust and viruses.

26 Mar 2021

New mathematical model identifies role of super-spreaders in SARS-CoV-2 variant emergence

Researchers have developed a new mathematical model which helps characterize factors responsible for the emergence of new SARS-CoV-2 variants and their predominance.

26 Mar 2021

One dose of Pfizer vaccine generates strong immune response against COVID-19

A new study led by the Universities of Sheffield and Oxford with support from the UK Coronavirus Immunology Consortium (UK-CIC) has found that 99 per cent of people generate a robust immune response against Covid-19 after just one dose of the Pfizer vaccine.

26 Mar 2021