T Cell News and Research

Latest T Cell News and Research

New platform using green algae tests for SARS-CoV-2 virus

Researchers at the University of California, San Diego, have demonstrated the potential of using green algae to make recombinant viral proteins that could be used in large scale assays to detect antibodies against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) - the agent that causes coronavirus disease 2019 (COVID-19).

1 Feb 2021

Granulocyte changes could help predict patient outcomes in COVID-19

Researchers in Sweden have provided a comprehensive characterization of circulating granulocytes in people infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19).

1 Feb 2021

Early induction of functional SARS-CoV-2-specific T cells linked with mild symptoms in COVID-19 patients

Humoral and cellular adaptive immunity are two immune mechanisms that act against pathogens. Humoral immunity is mediated by antibodies, while cellular immunity does not involve antibodies and is, instead, facilitated by T cells.

1 Feb 2021

New WHO guidelines provide recommendations for managing chronic pain in children

Chronic pain or pain that persists or recurs for longer than three months in children is a significant public health problem and a leading cause of morbidity in children globally.

1 Feb 2021

Life-threatening genetic immunodeficiency reversed by a rare DNA change

Researchers have revealed how a rare DNA change rebalanced the immune system of patients with a life-threatening genetic immunodeficiency.

1 Feb 2021

NYU Dentistry researcher receives NIH grant to study mitochondrial permeability transition

The National Institute of General Medical Sciences, part of the National Institutes of Health, has awarded NYU College of Dentistry's Evgeny Pavlov a grant to study a phenomenon called mitochondrial permeability transition, one of the central causes of tissue damage during stroke and heart attack.

1 Feb 2021

Groundbreaking therapy may provide a new treatment modality for biofilm infections in foot ulcers

A new £1.7m project to explore using plasma jets and antimicrobial dressings to treat debilitating - and potentially deadly - wound infections launches today.

1 Feb 2021

Can metformin reduce mortality in diabetic individuals with severe COVID-19?

A new study by researchers in China and the U.S. describes a round-up of the effects of commonly used hypoglycemic drugs on the outcomes of COVID-19 in diabetic patients.

1 Feb 2021

Deep learning method for gesture tracking and neural activity segmentation in mice

In order to find a causal relationship between neural activity and physical activities, neuroscientists usually record animals' behavior and their brain activity in a controlled environment.

1 Feb 2021

Enriched diet and companionship can reduce pain in mice with sickle cell disease

Researchers from the University of California, Irvine and the University of Minnesota have found that an enriched diet and companionship can reduce pain in mice with sickle cell disease by increasing serotonin.

1 Feb 2021

Protein alteration contributes to degeneration of neuronal populations in Huntington's disease

Protein alteration in the family of lamins causes several diseases, known as laminopathies, such as progeria or precocious aging.

1 Feb 2021

Gene panel is effective at identifying problematic genes in common leukemia

A gene panel that looks for about 10 times the number of cancer-causing genes as panels currently used to diagnose and fine-tune treatment for a variety of cancers is effective at identifying problematic genes in the most common leukemia, investigators report.

1 Feb 2021

Inhaled single dose vaccine creates antibodies and prevents infection in rhesus macaques

Now, a new preprint research paper describes a chimpanzee adenovirus-vectored vaccine that, when administered intranasally in rhesus macaques, led to a robust immune response and demonstrated protection against infection by the virus that causes COVID-19, namely, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The preprint is published on the bioRxiv server.

1 Feb 2021

India's Covaxin vaccine likely effective against UK SARS-CoV-2 variant: Study

A new preprint research paper, posted to the preprint server bioRxiv, presents data indicating that the Indian-made Covaxin vaccine candidate successfully neutralizes this variant, preventing infection when challenged by it.

1 Feb 2021

Phase III study of (m)RNA expression did not confer significant advantage for stage II-III lung cancer

A phase III study examining whether messenger (m)RNA expression correlated with sensitivity or resistance to chemotherapy did not confer a statistically significant advantage in overall survival for patients with resected stage II-III non-small cell lung cancer (NSCLC), according to research presented at the International Association for the Study of Lung Cancer World Conference on Lung Cancer.

31 Jan 2021

LCMC3 trial: Neoadjuvant atezolizumab prior to lung cancer surgery meets primary endpoint

(Primary analysis of the Lung Cancer Mutation Consortium (LCMC) 3 study revealed that neoadjuvant atezolizumab prior to lung cancer surgery was well tolerated by patients and met its primary endpoint of 20% major pathologic response rate, according to research presented today at the International Association for the Study of Lung Cancer's World Conference on Lung Cancer.

31 Jan 2021

SARS-CoV-2-specific T cells are key players in decreasing COVID-19 mortality

A recent US study, currently available on medRxiv preprint server, supports a beneficial rather than immunopathologic role for effector T-cells during serious infections with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) –

31 Jan 2021

Synergistic effect between NF-κB inhibitors and zinc in vitro reducing ACE2 expression

Researchers at National Taiwan University Hospital in Taipei have conducted a study demonstrating the potential effectiveness of a novel drug combination at reducing morbidity and mortality in coronavirus disease 2019 (COVID-19).

31 Jan 2021

Crystal structures of nanobodies could aid the design of COVID-19 therapies

Researchers at the National Institutes of Health in Bethesda, Maryland, have shown how certain synthetic nanobodies bind to the agent that causes coronavirus disease 2019 (COVID-19) – a development that could help inform the design of therapies.

31 Jan 2021

DSMB recommends continuation of Phase 2/3 study of opaganib for severe COVID-19

RedHill Biopharma Ltd., a specialty biopharmaceutical company, today announced that the independent Data Safety Monitoring Board (DSMB) for the global Phase 2/3 study of opaganib in patients with severe COVID-19, unanimously recommended to continue the study following a pre-scheduled futility review of unblinded efficacy data from the first 135 patients treated in the study and safety data from the first 175 patients.

30 Jan 2021

T Cell News and Research

Latest T Cell News and Research

New platform using green algae tests for SARS-CoV-2 virus

Granulocyte changes could help predict patient outcomes in COVID-19

Early induction of functional SARS-CoV-2-specific T cells linked with mild symptoms in COVID-19 patients

New WHO guidelines provide recommendations for managing chronic pain in children

Life-threatening genetic immunodeficiency reversed by a rare DNA change

NYU Dentistry researcher receives NIH grant to study mitochondrial permeability transition

Groundbreaking therapy may provide a new treatment modality for biofilm infections in foot ulcers

Can metformin reduce mortality in diabetic individuals with severe COVID-19?

Deep learning method for gesture tracking and neural activity segmentation in mice

Enriched diet and companionship can reduce pain in mice with sickle cell disease

Protein alteration contributes to degeneration of neuronal populations in Huntington's disease

Gene panel is effective at identifying problematic genes in common leukemia

Inhaled single dose vaccine creates antibodies and prevents infection in rhesus macaques

India's Covaxin vaccine likely effective against UK SARS-CoV-2 variant: Study

Phase III study of (m)RNA expression did not confer significant advantage for stage II-III lung cancer

LCMC3 trial: Neoadjuvant atezolizumab prior to lung cancer surgery meets primary endpoint

SARS-CoV-2-specific T cells are key players in decreasing COVID-19 mortality

Synergistic effect between NF-κB inhibitors and zinc in vitro reducing ACE2 expression

Crystal structures of nanobodies could aid the design of COVID-19 therapies

DSMB recommends continuation of Phase 2/3 study of opaganib for severe COVID-19

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T Cell News and Research

Latest T Cell News and Research

Immunology eBook

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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