T Cell News and Research

Latest T Cell News and Research

New screening method tests the effectiveness of drug compounds that 'glue' proteins together

A new screening method that can test the effectiveness of therapeutic molecules designed to 'glue' proteins together in the body has been developed by researchers at the University of Birmingham and the University of Leicester.

7 Jul 2021

Can memory T cell responses to seasonal coronaviruses protect against severe COVID-19?

In a recent study published in the journal Science Immunology, scientists have revealed that the presence of CD8+ T cells against conserved epitopes of seasonal coronaviruses is associated with mild coronavirus disease 2019 (COVID-19). These immune cells exhibit a memory phenotype and provide protection against severe disease.

7 Jul 2021

Mother-to-baby SARS-CoV-2 transmission in pregnancy possible but rare, says study

A new meta-analysis, released on the medRxiv* preprint server, suggests that, though possible, the virus is rarely transmitted to the newborn in real life. A scientific brief from the World Health Organization (WHO) in February 2021 describes three mechanisms by which the virus might be transmitted from the mother to the fetus or newborn.

7 Jul 2021

New study reports low SARS-CoV-2 breakthrough infections in vaccinated healthcare workers

Researchers examined cases of SARS-CoV-2 infection in fully and partially vaccinated healthcare workers, finding that vaccination provided strong immunity to the virus even though VOCs are on the rise in the non-vaccinated community at large.

7 Jul 2021

Rare genetic variants have a big impact on the risk of developing type 2 diabetes

Scientists at the University of Cambridge have identified rare genetic variants - carried by one in 3,000 people - that have a larger impact on the risk of developing type 2 diabetes than any previously identified genetic effect.

7 Jul 2021

Discovery of SARS-CoV-2–induced pathways uncovers groundbreaking drug repurposing strategies

A new study has been published in Science Advances that exploits proteomics datasets to develop an agnostic network for SARS-CoV-2–induced pathways, thereby unveiling novel targets and potential repurposing strategies.

7 Jul 2021

New technique provides deep tissue high-resolution images 100 to 1,000 times faster than other techniques

The new system, identified as DEEP, overcomes previous challenges with deep tissue microscopy and may revolutionize imaging methodology.

7 Jul 2021

Study addresses potential interrelations between AID/APOBECs and the SARS-CoV-2 virus

Together with their multifaceted action mechanisms, activation-induced cytidine deaminase (AID) and so-called APOBEC proteins are important factors in the body's immune response and offer fast and effective protection against a large number of DNA and RNA viruses.

7 Jul 2021

Study identifies specialized immune cells that sculpt inhibitory neurons to regulate brain wiring

From the bark of a puppy to the patter of rain against the window, our brains receive countless signals every second. Most of the time, we tune out inconsequential cues--the buzz of a fly, the soft rustle of leaves in the tree--and pay attention to important ones--the sound of a car horn, a bang on the door.

7 Jul 2021

Research shows how loss of de-N-glycosylation enzyme causes detrimental effects

Peptide: N-glycanase (NGLY1) is an evolutionarily conserved enzyme for removing N-linked glycans (N-glycans) from glycoproteins and is involved in proteostasis of N-glycoproteins in the cytosol. In 2012, a rare genetic disorder called NGLY1 deficiency was discovered by an exome analysis.

7 Jul 2021

Shape of extracellular vesicles in body fluids could be a biomarker for identifying cancer types

A recent study by scientists from Japanese universities has shown that the shape of cell-derived nanoparticles, known as "extracellular vesicles" (EVs), in body fluids could be a biomarker for identifying types of cancer.

7 Jul 2021

Study unravels the link between chromosomal instability and cellular senescence

Chromosomal instability is a feature of solid tumours such as carcinoma. Likewise, cellular senescence is a process that is highly related to cellular ageing and its link to cancer is becoming increasingly clear. Scientists led by ICREA researcher Dr. Marco Milán at IRB Barcelona have revealed the link between chromosomal instability and cellular senescence.

7 Jul 2021

Skin pigmentation mechanism confers major protection against UV-related cancers

A skin pigmentation mechanism that can darken the color of human skin as a natural defense against ultraviolet (UV)-associated cancers has been discovered by scientists at Massachusetts General Hospital (MGH).

7 Jul 2021

First synthetic circuit consists of entirely fast, reversible protein-protein interactions

Synthetic biology offers a way to engineer cells to perform novel functions, such as glowing with fluorescent light when they detect a certain chemical. Usually, this is done by altering cells so they express genes that can be triggered by a certain input.

7 Jul 2021

Synthetic defective SARS-CoV-2 could be used as a self-promoting antiviral therapy

What if the COVID-19 virus could be used against itself? Researchers at Penn State have designed a proof-of-concept therapeutic that may be able to do just that. The team designed a synthetic defective SARS-CoV-2 virus that is innocuous but interferes with the real virus's growth, potentially causing the extinction of both the disease-causing virus and the synthetic virus.

7 Jul 2021

COVID-19 vaccination may be stemming evolution of “fitter” SARS-CoV-2 variants

Researchers in the United States and India have presented the first known evidence that the rollout of coronavirus disease 2019 (COVID-19) vaccination is restricting the evolutionary and immune escape pathways accessible to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

6 Jul 2021

Moderna’s COVID-19 vaccine elicits durable T cell memory and antibody responses

Researchers in the United States have shown that Moderna’s mRNA-1273 coronavirus disease 2019 (COVID-19) vaccine induces durable antibody and T cell responses to the spike protein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that are comparable to those seen in cases of COVID-19 caused by natural SARS-CoV-2 infection.

6 Jul 2021

New discovery provides clues to elucidate the pathogenesis of muscle diseases

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T Cell News and Research

Latest T Cell News and Research

New screening method tests the effectiveness of drug compounds that 'glue' proteins together

Can memory T cell responses to seasonal coronaviruses protect against severe COVID-19?

Mother-to-baby SARS-CoV-2 transmission in pregnancy possible but rare, says study

New study reports low SARS-CoV-2 breakthrough infections in vaccinated healthcare workers

Rare genetic variants have a big impact on the risk of developing type 2 diabetes

Discovery of SARS-CoV-2–induced pathways uncovers groundbreaking drug repurposing strategies

New technique provides deep tissue high-resolution images 100 to 1,000 times faster than other techniques

Study addresses potential interrelations between AID/APOBECs and the SARS-CoV-2 virus

Study identifies specialized immune cells that sculpt inhibitory neurons to regulate brain wiring

Research shows how loss of de-N-glycosylation enzyme causes detrimental effects

Shape of extracellular vesicles in body fluids could be a biomarker for identifying cancer types

Study unravels the link between chromosomal instability and cellular senescence

Skin pigmentation mechanism confers major protection against UV-related cancers

First synthetic circuit consists of entirely fast, reversible protein-protein interactions

Synthetic defective SARS-CoV-2 could be used as a self-promoting antiviral therapy

COVID-19 vaccination may be stemming evolution of “fitter” SARS-CoV-2 variants

Moderna’s COVID-19 vaccine elicits durable T cell memory and antibody responses

New discovery provides clues to elucidate the pathogenesis of muscle diseases

NYUAD researchers unlock an epigenetic code that allows liver regeneration

Scientists unravel how cell death is initiated on a molecular level

Immunology eBook

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Scalable, Smart, and Accessible: The Future of Lab Automation

Healthy Beginnings, Hopeful Futures: A Conversation with WHO’s Dr. Allotey

T Cell News and Research

Latest T Cell News and Research

Immunology eBook

CellVoyant's AI-Powered Vision for the Future of Cell Therapy

Scalable, Smart, and Accessible: The Future of Lab Automation

Healthy Beginnings, Hopeful Futures: A Conversation with WHO’s Dr. Allotey

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