Telomere News and Research

Latest Telomere News and Research

Researchers use precision genomics to search genetic mutations causing accelerated aging

Mayo Clinic researchers are using precision genomics to search for undiscovered, inheritable genetic mutations that cause accelerated aging. In a study recently published in Mayo Clinic Proceedings, researchers conducted a study assessing 17 patients with short telomere syndromes -; rare conditions that result in premature DNA and cellular deterioration.

6 Jul 2018

Scientists disrupt two enzymes to shrink cancer cells

Before cell division, the long strings of the cell's DNA are wrapped tightly into the structures we know as chromosomes. This protects the cell's genetic material from physical and chemical damage.

17 May 2018

Researchers target telomerase for killing NRAS-mutant melanoma cells

Targeting telomerase was effective at killing NRAS-mutant melanoma cells, and the impact was further enhanced when the strategy was paired with an inhibitor of mitochondrial function, according to study results by The Wistar Institute published in Oncogene.

26 Apr 2018

Study reports promising novel approach to treat therapy resistant pediatric brain tumors

Researchers used an experimental molecular therapy in preclinical laboratory tests to effectively treat several types of deadly pediatric brain cancer and now propose advancing the treatment to clinical testing in children.

17 Apr 2018

Targeting aberrantly active telomerase to treat therapy-resistant melanoma

A study conducted at The Wistar Institute in collaboration with The University of Texas Southwestern Medical Center has demonstrated the efficacy of targeting aberrantly active telomerase to treat therapy-resistant melanoma.

21 Mar 2018

Study finds link between women having children and shorter telomeres

A recent study by George Mason University researchers in the Department of Global and Community Health found that women who have given birth have shorter telomeres compared to women who have not given birth.

9 Mar 2018

Telomere length testing can alter treatment decisions for certain diseases

Research led by Johns Hopkins physicians and scientists shows that a test for measuring the length of DNA endcaps, called telomeres, which has a variability rate of 5 percent, can alter treatment decisions for patients with certain types of bone marrow failure.

27 Feb 2018

ASU researchers uncover crucial step in telomerase enzyme catalytic cycle

Can we stay young forever, or even recapture lost youth? Research from the laboratory of Professor Julian Chen in the School of Molecular Sciences at Arizona State University recently uncovered a crucial step in the telomerase enzyme catalytic cycle.

27 Feb 2018

3D Signatures reports positive results of new Telo-HL test for Hodgkin's lymphoma

3D Signatures Inc. is pleased to announce that a preliminary third-party analysis of the trial data for Telo-HL, 3DS' test in development for Hodgkin's lymphoma (HL), shows that the Company's TeloViewTM platform is able to distinguish, with a high degree of statistical significance, multiple differences between a patient group that responds to standard ABVD chemotherapy, and a group that relapses or is refractory to treatment within the first 12 months.

22 Feb 2018

CAR-T therapy saves life of cancer researcher

About a dozen years ago, Dr. Woodring Wright, a UT Southwestern Professor of Cell Biology, sneezed. It broke one of his vertebrae, the interlocking bones that make up the spinal column.

14 Feb 2018

Researchers develop gene therapy for idiopathic pulmonary fibrosis

Researchers have successfully identified the genetic cause of idiopathic pulmonary fibrosis and have shown success in trials of a new gene therapy.

1 Feb 2018

Long-term intake of sunflower, fish oils affects the liver

An international group of scientists led by the University of Granada (UGR) has demonstrated that the long-term intake of sunflower or fish oils damages the liver and can cause a series of alterations in it, giving rise to non-alcoholic steatohepatitis.

31 Jan 2018

Researchers use gene therapy that lengthens telomeres to cure pulmonary fibrosis in mice

Idiopathic pulmonary fibrosis is a potentially lethal disease associated with the presence of critically short telomeres, currently lacking effective treatment.

30 Jan 2018

Research provides insights into mechanisms governing healthy longevity

Keio University Global Research Institute, Tokyo publishes the January 2018 issue of KGRI Research Frontiers that includes researcher video profiles of Keio University researchers and research highlights from high impact publications including 'Regenerative medicine needs collaboration in and out of science in order to face current and future challenges; ‘Does eating fish protect you from depression?’; ‘Insights into the molecular mechanisms leading to kidney dysfunction in diabetic patients’; and ‘Ageing to 100 and beyond: Insights from demographic, phenotypic and genetic studies.

12 Jan 2018

Bipolar disorder may involve accelerated epigenetic aging, study finds

Bipolar disorder may involve accelerated epigenetic aging, which could explain why persons with the disorder are more likely to have - and die from - age-related diseases, according to researchers from The University of Texas Health Science Center at Houston.

12 Dec 2017

Simple molecular test may help predict presence of high-grade pancreatic cancers

A report in The Journal of Molecular Diagnostics, describes a new simple molecular test to detect chromosomal abnormalities -- biomarkers known as telomere fusions--in pancreatic tumor specimens and pancreatic cyst fluids.

8 Dec 2017

Aging tests disagree with one another

Whether it's an on-line quiz, a $300 chromosome test or an $800 blood panel, a lot of people seem to be interested in whether they're aging faster or slower than their chronological age would suggest.

16 Nov 2017

Effects of having familiar, good neighbors revealed in bird study

Birds who live next door to family members or to other birds they know well are physically healthier and age more slowly, according to new research from the University of East Anglia.

10 Oct 2017

Penn researchers find abnormally shortened telomeres in young DMD patients’ muscle stem cells

Researchers from the Perelman School of Medicine at the University of Pennsylvania have made a discovery about muscular dystrophy disorders that suggest new possibilities for treatment.

7 Sep 2017

Researchers find correlation between shorter telomeres and presence of heart failure

Each cell in the average human body contains 23 pairs of chromosomes, with four telomeres on each pair. Telomeres cover the end of the chromosome, protecting it from deterioration or fusion with adjacent chromosomes, much like the plastic tip at the end of a shoelace protects it from unraveling.