Thrombosis News and Research

Latest Thrombosis News and Research

HIV agent offers HER2-positive breast cancer hope

A drug used to treat HIV infection may be a new treatment line for patients with an aggressive type of breast cancer, US researchers believe.

15 Oct 2012

Obesity does not affect VTE risk after knee surgery

Being morbidly obese does not increase the risk for developing venous thromboembolism after total knee arthroplasty surgery, report US researchers.

15 Oct 2012

Rheumatoid arthritis treatment foiled by gum disease

Periodontal disease may reduce the efficacy of tumor necrosis factor inhibitor treatment in patients with rheumatoid arthritis, preliminary research suggests.

15 Oct 2012

METASTROKE refines genetic stroke culprits

An analysis from the METASTROKE collaboration confirms an increased stroke risk associated with four previously reported genetic loci and shows that these are specific to certain stroke subtypes.

15 Oct 2012

Therapeutic HPV16 and HPV18 vaccine ‘may eliminate infection’

A candidate vaccine against human papillomavirus serotypes 16 and 18 appears to induce robust immune responses to antigens, potentially leading to the elimination of virus-infected cells and regression of dysplasia, say US investigators.

15 Oct 2012

Celgene receives FDA approval for ABRAXANE to treat non-small cell lung cancer

Celgene Corporation today announced the U.S. Food and Drug Administration (FDA) has approved ABRAXANE (paclitaxel protein-bound particles for injectable suspension) (albumin-bound) for the first-line treatment of locally advanced or metastatic non-small cell lung cancer, in combination with carboplatin, in patients who are not candidates for curative surgery or radiation therapy.

15 Oct 2012

Hip arthroscopy traction weight key to nerve outcome

Minimizing traction weight during hip arthroscopy in the lateral position may protect against sciatic nerve injury, report US surgeons.

12 Oct 2012

Further evidence against sun bed use

Results from a systematic review and meta-analysis published in the BMJ confirm those from previous studies linking sun bed use with an increased risk for skin cancer.

12 Oct 2012

One rule for one and one for another with diabetes

A joint consensus statement from the European Association for the Study of Diabetes and the American Diabetes Association encourages a shift in attitude over glycemic management in Type 2 diabetes.

12 Oct 2012

Perimetry identifies visual function changes in diabetic retinopathy

Perimetry could be adopted as a method to measure changes in visual function among individuals with diabetic retinopathy, show promising results from a prospective longitudinal study undertaken in Sweden.

12 Oct 2012

Lenalidomide worsens survival, adverse events in prostate cancer

A combination of lenalidomide plus docetaxel and prednisone treatment in patients with chemotherapy-naive prostate cancer leads to worse overall survival rates and increased toxicity compared with placebo, show study results.

12 Oct 2012

Key to eczema’s itch uncovered

An influx of neutrophils that secrete a lipid called leukotriene B4 is responsible for triggering the itching and inflammation of the skin typically seen in patients with eczema, suggest study findings.

12 Oct 2012

Tourniquet timing alters foot surgery pain outcomes

The timing of thigh tourniquet application may affect pain control in patients undergoing forefoot surgery, research published in Foot and Ankle Surgery suggests.

11 Oct 2012

UK acid-related disease trends revealed

The incidence of Barrett’s esophagus in the UK has doubled in recent years, but the incidence of gastroesophageal reflux disease is stable, study findings reveal.

11 Oct 2012

Tomatoes every day may keep stroke at bay

Regular consumption of tomatoes and other lycopene-rich fruits and vegetables may help reduce a man’s risk for stroke, suggest study findings.

11 Oct 2012

Public reporting states have low angioplasty rates

US states in which public reporting of percutaneous coronary intervention rates by catheterization laboratories is required may have a reduced rate of the procedure in acute myocardial infarction patients, research suggests.

11 Oct 2012

Tissue test detects oral cancer risk

A molecular diagnostic scoring system based on patients’ FOXM1-associated gene messenger RNA expression levels is able to quantitatively diagnose and stratify oral carcinoma and its aggressiveness, show UK and Norwegian study results.

11 Oct 2012

Heart drug could ease rare muscle disorder

The anti-arrhythmic drug mexiletine may improve symptoms in patients with nondystrophic myotonias, shows a small randomized trial published in JAMA.

11 Oct 2012

MDD with subthreshold hypomania ‘should be merged with bipolar II’

Patients with major depressive disorder plus subthreshold hypomania exhibit significant differences in disease course, symptoms, treatment-seeking rates, and other characteristics compared with those with major depression alone, research shows.

11 Oct 2012

Inhaled corticosteroids increase Staphylococcus pneumoniae infection risk

Regular use of inhaled corticosteroids by asthmatic children increases their risk for oropharyngeal colonization with Staphylococcus pneumoniae almost fourfold, research suggests.

10 Oct 2012