Thrombosis News and Research

Latest Thrombosis News and Research

Drug-releasing stent shows promise for improving outcomes in patients with coronary artery disease

For patients who underwent angioplasty to open narrowed coronary arteries, the use of stents releasing the drug everolimus reduced the rate of renarrowing of the arteries and significantly reduced the risk of major cardiac events, compared to the widely-used paclitaxel-releasing stents, according to a study in the April 23/30 issue of JAMA, the Journal of the American Medical Association.

22 Apr 2008

Peripheral arterial disease linked to too little vitamin D

According to the results of the latest research peripheral arterial disease (PAD) may be linked to low levels of vitamin D.

21 Apr 2008

Study results on novel drug-eluting stent coated with a biodegradable polymer

"Real-world" use of a novel drug-eluting stent coated with a biodegradable polymer is associated with good clinical outcomes, according to one-year data from a large international registry.

1 Apr 2008

Disappointing resuts for pimecrolimus, investigational anti-restenosis drug

A new medication that researchers had hoped would reduce the risk of arterial renarrowing after stenting has turned in a disappointing performance in a multicenter clinical trial, but the multi-reservoir stent that was used to deliver the drug is still considered promising.

1 Apr 2008

Matrix registry probes adherence to clopidogrel at 1 year

A large community-based registry of patients treated with drug-eluting stents is providing important insight into how long patients with complex coronary artery disease typically stick to their doctors' orders to take clopidogrel, a drug that prevents unwanted blood clots; why they stop taking the drug; and the long-term consequences of that decision.

1 Apr 2008

Study looks at use of powerful anticoagulants to prevent pulmonary embolism

Current US guidelines for the prescription of potent anticoagulants by surgeons who perform joint replacement operations could be doing patients more harm than good, according to Dr. Nigel Sharrock and his team from the Hospital for Special Surgery in New York.

1 Apr 2008

Study gives nod to drug-eluting stents in heart attack

Although drug-eluting stents have become widely used for the treatment of stable coronary artery disease, many cardiologists choose bare-metal stents for patients with heart attack, or myocardial infarction (MI), citing conflicting data about the safety and effectiveness of drug-eluting stents in this patient group.

31 Mar 2008

Drug-eluting stents outperform bare-metal stents

New evidence from a large randomized study is answering important questions about the best approach to percutaneous coronary intervention (PCI) in patients with a type of heart attack known as ST-segment-elevation myocardial infarction (STEMI).

31 Mar 2008

Repeated episodes of stent thrombosis common

When a clot develops inside a coronary stent, it can block blood flow to the heart, potentially causing a heart attack or even death.

31 Mar 2008

Several methods for enhancing the functioning of defibrillators in cases of heart attack

The PhD, defended by engineer Sofia Ruiz de Gauna Gutierrez at the University of the Basque Country (UPV/EHU) puts forward various methods for the elimination of interference caused by compressions and ventilations of cardiopulmonary resuscitation in the context of cardiac defibrillation.

26 Mar 2008

Coagulation in patients with anxiety disorders

"The blood froze in my veins" or "My blood curdled" - these common figures of speech can be taken literally, according to the latest studies.

26 Mar 2008

First clinical trial data of a fully bioabsorbable drug-eluting stent

Data published today in The Lancet from ABSORB, the world's first clinical trial of a fully bioabsorbable drug eluting stent for the treatment of coronary artery disease, demonstrated no stent thrombosis, no clinically driven target lesion revascularizations (re-treatment of a diseased lesion), and a low (3.3 percent) rate of major adverse cardiac events (MACE) in 30 patients out to one year.

14 Mar 2008

Damaged veins heal faster with heparin treatment, laboratory study finds

A commonly used medication that prevents blood clots from forming may also prevent existing clots from damaging delicate vein walls and may accelerate healing in a clot-damaged area of vein wall, according to new research from the University of Michigan Cardiovascular Center.

14 Mar 2008

Is deep-vein thrombosis lurking in your legs?

They kill 300,000 people a year - but most of them could be prevented. They strike more than a million people every year, most of them out of the blue - and half without causing symptoms.

14 Mar 2008

Discovery of potential drug targets for sepsis

"We have identified a key connection of signaling pathways in the cascade of events leading to sepsis. This defines a crucial point where the immune system spirals out of control to cause severe sepsis and where there is an opportunity for therapeutic intervention," says Scripps Research Professor Wolfram Ruf, who led the research with his postdoctoral fellow Frank Niessen.

28 Feb 2008