Thrombosis News and Research

Latest Thrombosis News and Research

Compression stockings help prevent deep vein thrombosis

People wearing compression stockings on long-haul flights may have one tenth the risk of developing a deep vein thrombosis (DVT) compared to those who do not wear compression stockings. So concludes a systematic review of medical research to be published in The Cochrane Library.

18 Apr 2006

Possible alternatives found for Vioxx and Celebrex

According to Canadian and American researchers they have identified one reason why drugs like Celebrex and Vioxx - once popular for the treatment of pain and inflammation - cause heart problems.

18 Apr 2006

Researchers clarify the mechanism by which drugs like Celebrex and Vioxx cause heart problems

Researchers at the University of Pennsylvania School of Medicine have clarified the mechanism by which drugs like Celebrex and Vioxx cause heart problems, in multiple animal models.

18 Apr 2006

Osteoporosis drug Raloxifene shown to be as effective as Tamoxifen in preventing invasive breast cancer

Initial results of the Study of Tamoxifen and Raloxifene, or STAR, show that the drug raloxifene, currently used to prevent and treat osteoporosis in postmenopausal women, works as well as tamoxifen in reducing breast cancer risk for postmenopausal women at increased risk of the disease.

18 Apr 2006

Sildenafil improves blood flow after heart attack in an animal model

Dogs treated with sildenafil, a drug most commonly used to treat erectile dysfunction, had better blood flow in coronary arteries than control animals, following an induced artery obstruction and treatment that modeled a heart attack and standard medical care given to people

13 Apr 2006

Estrogen therapy increases the risk of blood clots in some women

According to new research postmenopausal women on estrogen therapy who have undergone a hysterectomy have an elevated risk of developing a blood clots in veins.

11 Apr 2006

Estrogen therapy may increase the risk of venous thrombosis

Estrogen therapy may increase the risk of venous thrombosis, the formation of blood clots in the veins, among postmenopausal women who have had their uterus removed, according to a study in the April 10 issue of Archives of Internal Medicine.

11 Apr 2006

Fish oil significantly reduces production of various prostaglandins that accentuate inflammation and thrombosis

Omega 3 fatty acids in dietary fish oil are reported to have anti-inflammatory and anti-thrombogenic and anti-arrhythmic effects in humans, but the biochemical basis for these beneficial health effects is not well understood.

4 Apr 2006

The safety and effectiveness of fondaparinux for heart attacks

The results of a large international cardiovascular trial will shed light on whether the addition of a new drug that prevents blood clotting, or thrombosis, can improve the treatment of the most serious form of heart attacks.

15 Mar 2006

Low pressure and low oxygen factors in DVT and long flights

Researchers say that the risk of deep vein thrombosis (DVT) during flights may not be due simply to sitting still; they say the low pressure and low oxygen environment during air travel may also contribute to the development of deep vein thrombosis in some susceptible individuals.

13 Mar 2006

Stents that release the drug paclitaxel to treat stenosis more effective than radiation therapy

Insertion of stents that release the drug paclitaxel to treat stenosis within an implanted bare-metal stent in a coronary artery reduces the risk of subsequent re-narrowing within the stent, when compared with treatment using intra-coronary radiation

13 Mar 2006

Drug-eluting stents best treatment for managing coronary restenosis

In the first published trial of its kind, a multi-center clinical study has shown that drug-eluting stents outperform the current "gold standard" radiation treatment in managing coronary restenosis and in preventing further clogging of coronary arteries.

13 Mar 2006

Thalidomide improves remission in myeloma

Myeloma is one of the least curable cancers and involves plasma cells, the white blood cells that produce antibodies.

9 Mar 2006

Inflammation is a crucial and dangerous step in the development of obesity

New research by the University of Warwick's Warwick Medical School shows that the biggest health threat to fat and obese people isn't the fat itself but the fact that the fat fuels a killer inflammation response in people.

8 Mar 2006

Study may lead to ways to reduce heart attacks in diabetes patients

For people with type 2 diabetes, the death rate from a first heart attack is two to three times the death rate of patients without the disease. Similarly, patients with diabetes and ischemic (reduced blood flow) heart disease have a much higher mortality rate than the general population.

7 Mar 2006

Coronary stents that release the drugs sirolimus or paclitaxel produce similar results

Use of coronary stents that release the drugs sirolimus or paclitaxel produced similar results in patients with new coronary artery lesions, according to a study in JAMA: The Journal of the American Medical Association.

24 Feb 2006

Alternative method to produce heparin

Researchers at Rensselaer Polytechnic Institute and University of North Carolina at Chapel Hill have discovered an alternative way to produce heparin, a drug commonly used to stop or prevent blood from clotting.

7 Feb 2006

FDA fast track status for Alfimeprase

Nuvelo Inc. today announced that it has been granted fast track designation by the U.S. Food and Drug Administration (FDA) for its lead product candidate, alfimeprase, for the treatment of acute peripheral arterial occlusion (PAO), or "leg attack."

23 Jan 2006

Aspirin can significantly reduce the risk of cardiovascular events

Aspirin can significantly reduce the risk of cardiovascular events -- a combined endpoint including stroke, heart attack and death due to cardiovascular disease -- in both men and women, according to a new meta-analysis of more than 95,000 patients by a Duke University Medical Center cardiologist.

18 Jan 2006

Thalomid gives hope for blood cancer sufferers

Drug company Celgene says it has halted a pivotal-stage trial of its Thalomid drug earlier than expected after the drug was shown to dramatically limit the progress of the blood cancer multiple myeloma.

9 Jan 2006