Thrombosis News and Research

Latest Thrombosis News and Research

MorphoSys receives clinical milestone for start of Phase 1 trial in prevention of thrombosis with novel antibody

MorphoSys AG announced that it has received a milestone payment from Novartis in connection with the initiation of a clinical phase 1 trial with a novel HuCAL antibody. The antibody will be tested in the field of prevention of thrombosis. This is the twelfth therapeutic antibody based on MorphoSys's technologies that Novartis is evaluating in clinical trials. Financial details were not disclosed.

6 Jul 2016

Novel blood coagulation analyzer may help detect stroke risk in AF patients

Researchers at Tokyo Medical and Dental University show that an analyzer recently developed to measure blood coagulability has the sensitivity to detect hypercoagulatibility associated with stroke risk in those without atrial fibrillation

4 Jul 2016

Omega-3 PUFA biomarkers demonstrate benefits for fatal CHD

Regular consumption of seafood and plant-based omega-3 polyunsaturated fatty acids could help lower the risk of fatal coronary heart disease, confirm findings from a pooled analysis of 19 studies.

30 Jun 2016

New magnetically controlled drug safe, effective in dissolving blood clots

Critical conditions associated with the blockage of blood vessels are one of the primary health concerns worldwide.

22 Jun 2016

MicroRNA plays role in blocking development of arterial thrombosis

The dangers of arterial thrombosis - the formation of blood clots that can block arteries and cause illness or death - can escalate through a vicious cycle of coagulation and inflammation.

15 Jun 2016

New RNA aptamer can prevent pathogenic protein misfolding

Several diseases occur when mutations cause misfolding of proteins. These include "serpinopathies" which is a group of rare heritable diseases. They are caused by mutations of so-called "serpin" inhibitors of proteolytic enzymes involved in blood coagulation, tissue remodeling, and other important physiological functions.

10 Jun 2016

Betrixaban scores near miss for extended thromboprophylaxis

Extended thromboprophylaxis with the direct factor Xa inhibitor betrixaban just fails to show superiority to standard treatment with enoxaparin in acutely ill medical patients.

1 Jun 2016

SIPPET study may have implications for treatment of patients with severe hemophilia A

SIPPET, a study which involved 42 centers in 14 countries in Europe, North and South America, Africa and Asia was designed to definitively settle the long-debated question whether factor VIII concentrates from different sources (plasma-derived containing VWF or recombinant technology) differ in risk of inhibitor development in previously untreated children (PUPs) with severe hemophilia A.

28 May 2016

Bare metal stents no longer advisable for high bleeding risk ACS patients

A polymer-free, drug-coated stent gives markedly better outcomes than a bare metal stent in patients with acute coronary syndromes and risk factors for bleeding, report researchers.

24 May 2016

Pre-procedural use of antiplatelet therapy becoming less routine in heart attack treatment

Doctors worried about dangerous blood clots in patients undergoing a coronary artery procedure— such as angioplasty to treat a heart attack — will often administer antiplatelet therapy to head off complications.

22 May 2016

PCI with polymer-free BA9 drug-coated stent better than bare metal stent in ACS patients

Patients with acute coronary syndromes (ACS) who are at high risk for bleeding have significantly lower rates of target lesion revascularisation and fewer adverse events after undergoing percutaneous coronary intervention (PCI) with a polymer-free biolimus-A (BA9) drug-coated stent than with those receiving a bare metal stent (BMS) in results from a sub-study of the LEADERS FREE trial reported for the first time in a late-breaker session at EuroPCR 2016.

17 May 2016

Minihepcidins may potentially treat serious genetic blood diseases in children, adults

New research suggests that synthetic peptides called minihepcidins may potentially treat two serious genetic blood diseases in children and adults. Although those diseases, beta-thalassemia and polycythemia vera, have opposite effects on red blood cell production, treating animals with minihepcidin helps to restore normal levels of red blood cells and reduces spleen enlargement. It also controls the accumulation of excess levels of iron in beta-thalassemia that often causes severe toxic effects.

9 May 2016

Reasons for life-threatening blood clots in elite athletes

Mary Cushman, M.D., M.Sc., a professor of medicine and director of the Thrombosis and Hemostasis Program at the University of Vermont, provides commentary on the causes of life-threatening blood clots in elite athletes.

6 May 2016

Increased fitness can normalize platelet function quickly

Women with poor physical fitness display significantly higher platelet activation than women with average to very good fitness. That is the major finding of a study of 62 young women, conducted by the research groups of Ivo Volf and Rochus Pokan and sponsored by the Austrian Heart Foundation. Platelet (thrombocyte) activation can lead to the formation of potentially life-threatening blood clots.

3 May 2016

Study explores benefits of hand and shoulder surgeries performed at outpatient centers

A large study of hand and shoulder surgeries performed at a freestanding, outpatient center found few complications--0.2 percent in nearly 29,000 patients over an 11-year period. The study appears in the new issue of the Journal of Bone and Joint Surgery.

22 Apr 2016

Interdisciplinary researchers to explore ethical issues of pregnant women during Zika crisis

The emerging Zika virus epidemic is bringing to light a longstanding ethical challenge in medical research: the inclusion of pregnant women. With new funding from the Wellcome Trust, an interdisciplinary team of scholars will focus on issues of ethics and research in pregnancy and women of reproductive age, beginning with the current Zika context and later expanding to general public health research.

15 Apr 2016

Aspirin resistance signals increased stroke severity

Stroke severity and infarct volume are significantly increased among patients who become resistant to aspirin, show study findings published in Neurology.

12 Apr 2016

Ariste Medical develops drug-eluting mesh for more effective open hernia repair

Ariste Medical has revealed new research outlining the company’s novel method for addressing medical device failure in open ventral hernia repair.

12 Apr 2016

Magnetically controlled enzyme solutions can be used for targeted treatment of cancer, thrombosis

Researchers from ITMO University, the Hebrew University of Jerusalem and Cyril and Methodius University in Skopje have fabricated a new magnetically controlled material composed of enzymes entrapped directly within magnetite particles.

7 Apr 2016

Micra Transcatheter Pacing System approved to treat heart rhythm disorders

The U.S. Food and Drug Administration today approved the first pacemaker that does not require the use of wired leads to provide an electrical connection between the pulse-generating device and the heart. While the Micra Transcatheter Pacing System works like other pacemakers to regulate heart rate, the self-contained, inch-long device is implanted directly in the right ventricle chamber of the heart.

7 Apr 2016

Thrombosis News and Research

Latest Thrombosis News and Research

MorphoSys receives clinical milestone for start of Phase 1 trial in prevention of thrombosis with novel antibody

Novel blood coagulation analyzer may help detect stroke risk in AF patients

Omega-3 PUFA biomarkers demonstrate benefits for fatal CHD

New magnetically controlled drug safe, effective in dissolving blood clots

MicroRNA plays role in blocking development of arterial thrombosis

New RNA aptamer can prevent pathogenic protein misfolding

Betrixaban scores near miss for extended thromboprophylaxis

SIPPET study may have implications for treatment of patients with severe hemophilia A

Bare metal stents no longer advisable for high bleeding risk ACS patients

Pre-procedural use of antiplatelet therapy becoming less routine in heart attack treatment

PCI with polymer-free BA9 drug-coated stent better than bare metal stent in ACS patients

Minihepcidins may potentially treat serious genetic blood diseases in children, adults

Reasons for life-threatening blood clots in elite athletes

Increased fitness can normalize platelet function quickly

Study explores benefits of hand and shoulder surgeries performed at outpatient centers

Interdisciplinary researchers to explore ethical issues of pregnant women during Zika crisis

Aspirin resistance signals increased stroke severity

Ariste Medical develops drug-eluting mesh for more effective open hernia repair

Magnetically controlled enzyme solutions can be used for targeted treatment of cancer, thrombosis

Micra Transcatheter Pacing System approved to treat heart rhythm disorders

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

Thrombosis News and Research

Latest Thrombosis News and Research

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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