Toxicology News and Research

Latest Toxicology News and Research

Low levels of miR-29 could reduce susceptibility to cardiac fibrosis

Cardiac fibrosis involves an increase of connective tissue in the cardiac muscle, causing a loss of function. A team of researchers at the Technical University of Munich has now discovered that microRNA 29 (miR-29) plays an important role in the formation of tissue fibrosis.

23 Nov 2017

Research suggests genome's spatial organization as important switch for defining cell types

During differentiation of pluripotent stem cells to cardiomyocytes, the three-dimensional folding of the DNA reorganizes itself. This reorganization of the DNA architecture precedes and defines important epigenetic patterns.

22 Nov 2017

Digital pills can help track opioid use patterns

Digital pills - gelatin capsules that contain an ingestible sensor along with medication - can help track patterns of drug use, and Brigham and Women's Hospital clinicians are among the first to explore the application of this new technology among patients being prescribed opioids.

20 Nov 2017

Chronic preconception exposure to genistein may adversely affect female fertility, mice study finds

Exposure to the phytoestrogen genistein prior to conception may adversely affect female fertility and pregnancy outcomes, depending on the dosage and duration of exposure, a new study in mice suggests.

14 Nov 2017

UB researcher explores link between signals in the brain's reward system and overeating, drug addiction

Why are some people able to stop after eating just a few potato chips, while others aren't satisfied until the bag is nothing but crumbs? The answer may lie in the signals acting in the brain's reward system.

9 Nov 2017

Novel approach could help predict how well patients respond to cancer treatment

A novel approach developed by researchers from the University of Leicester and the MRC Toxicology Unit could help to predict how well patients respond to drugs designed to fight various forms of cancer.

8 Nov 2017

Nicotine alters gut microbiome differently in males and females, mice study shows

Many people who smoke or chew tobacco can't seem to escape nicotine's addictive properties. Studies show that women in particular seem to have a harder time quitting, even with assistance, when compared to men.

3 Nov 2017

Scientists develop bioluminescent enzymatic test system for assessing toxicity of nanomaterials

Official website of the Russian Science Foundation reports that a group of scientists from Siberian Federal University and Krasnoyarsk Scientific Center of the SB RAS has developed a bioluminescent enzymatic test system for assessing the toxicity of carbon nanomaterials.

2 Nov 2017

Study shows effects of prenatal BPA exposure at low levels in developing rodent brain

New research from North Carolina State University reveals that prenatal exposure to bisphenol A (BPA) at levels below those currently considered safe for humans affects gene expression related to sexual differentiation and neurodevelopment in the developing rat brain.

31 Oct 2017

HCV screening or diagnosis could lower non‐prescribed opioid use

Research presented this week at The Liver Meeting – held by the American Association for the Study of Liver Diseases – shows people in treatment for opioid substance abuse significantly lowered their non‐prescribed opioid use after testing positive for hepatitis C virus.

20 Oct 2017

Study finds mitochondrial DNA damage in Veterans with Gulf War illness

Researchers say they have found the "first direct biological evidence" of damage in veterans with Gulf War illness to DNA within cellular structures that produce energy in the body.

19 Oct 2017

Study shows that endocrine disrupting chemicals alter sex ratio in Blanchard's cricket frogs

A study published recently in Environmental Toxicology and Chemistry found that Blanchard's cricket frogs are highly sensitive to atrazine.

13 Oct 2017

Awards for contributions to analytical chemistry and applied spectroscopy announced by Pittcon

The Pittcon Program Committee is pleased to announce this year’s recipients of 13 prestigious awards honoring scientists who have made outstanding contributions to analytical chemistry and applied spectroscopy. Each award will be presented in a scheduled symposium during Pittcon 2018, the world’s leading conference and exposition for laboratory science, which will be held February 26-March 1, Orange County Convention Center, Orlando, Florida.

From Pittcon 10 Oct 2017

Researchers look for ways to prevent chemotherapy-induced cognitive impairment

Of the 14 million cancer survivors in the United States, a significant number experience a serious side effect called chemotherapy-induced cognitive impairment (CICI). While easily recognized, little is known about the etiology of this condition, also known informally as "chemo brain."

3 Oct 2017

Novartis partners with UC Berkeley to pursue 'undruggable' disease targets

Novartis has joined forces with researchers from the University of California, Berkeley, to develop new technologies for the discovery of next-generation therapeutics, pursuing the vast number of disease targets in cancer and other illnesses that have eluded traditional small-molecule compounds and are considered "undruggable."

28 Sep 2017

Researchers find cancer-causing chemicals in vapor produced by cannabis extract

Researchers at Portland State University found benzene and other potentially cancer-causing chemicals in the vapor produced by butane hash oil, a cannabis extract.

27 Sep 2017

New tissue-chip research aims to speed drug development for two genetic forms of epilepsy

An interdisciplinary team of Vanderbilt University researchers has received a two-year, $2-million federal grant to develop an "organ-on-chip" model for two genetic forms of epilepsy. These disorders affect both brain and heart and improved modeling could lead to new drug treatments.

22 Sep 2017

Lead in water leading to problems with fertility and childbirth in Flint, Michigan

Researchers from the University of Kansas, Department of Economics in a new working paper series in Theoretical and Applied Economics write that with the change in water sources in Flint, Michigan since April 2014, lead exposure to the population has risen.

22 Sep 2017

Analytical Science in Precision Medicine

Pittcon is an analytical conference, so naturally my talk will be about analytical chemistry and how analytical chemistry will become increasingly important in delivering healthcare solutions, not only for rich people, but also, hopefully, for poor people across the world.

From Pittcon 19 Sep 2017

UofL gastroenterologist receives NIEHS award to explore effects of environmental chemicals on the liver

UofL gastroenterologist Matthew Cave, M.D., believes that chemicals we breathe, consume or come in contact with in the environment may be contributing to liver disease in as many as one in four people. He has been awarded $4.01 million over eight years by the National Institute of Environmental Health Sciences, one of the National Institutes of Health, to explore the long-term effects of environmental chemicals on the liver.

15 Sep 2017

Toxicology News and Research

Latest Toxicology News and Research

Low levels of miR-29 could reduce susceptibility to cardiac fibrosis

Research suggests genome's spatial organization as important switch for defining cell types

Digital pills can help track opioid use patterns

Chronic preconception exposure to genistein may adversely affect female fertility, mice study finds

UB researcher explores link between signals in the brain's reward system and overeating, drug addiction

Novel approach could help predict how well patients respond to cancer treatment

Nicotine alters gut microbiome differently in males and females, mice study shows

Scientists develop bioluminescent enzymatic test system for assessing toxicity of nanomaterials

Study shows effects of prenatal BPA exposure at low levels in developing rodent brain

HCV screening or diagnosis could lower non‐prescribed opioid use

Study finds mitochondrial DNA damage in Veterans with Gulf War illness

Study shows that endocrine disrupting chemicals alter sex ratio in Blanchard's cricket frogs

Awards for contributions to analytical chemistry and applied spectroscopy announced by Pittcon

Researchers look for ways to prevent chemotherapy-induced cognitive impairment

Novartis partners with UC Berkeley to pursue 'undruggable' disease targets

Researchers find cancer-causing chemicals in vapor produced by cannabis extract

New tissue-chip research aims to speed drug development for two genetic forms of epilepsy

Lead in water leading to problems with fertility and childbirth in Flint, Michigan

Analytical Science in Precision Medicine

UofL gastroenterologist receives NIEHS award to explore effects of environmental chemicals on the liver

Forensics And Toxicology eBook

Precision in every drop: Inside Hamilton’s syringe technology

Exploring the Future of Neuroscience Drug Discovery

Genomic conservation in Thailand's mangroves

Toxicology News and Research

Latest Toxicology News and Research

Forensics And Toxicology eBook

Precision in every drop: Inside Hamilton’s syringe technology

Exploring the Future of Neuroscience Drug Discovery

Genomic conservation in Thailand's mangroves

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