Toxicology News and Research

Latest Toxicology News and Research

Palatin introduces clinical trial website in support of bremelanotide phase 3 study for FSD treatment

Palatin Technologies, Inc., a biopharmaceutical company developing targeted, receptor-specific peptide therapeutics for the treatment of diseases with significant unmet medical needs and commercial potential, today announced that it has launched a clinical trial website in support of its phase 3 reconnect study with bremelanotide for the treatment of female sexual dysfunction (FSD).

20 Feb 2015

Doctoral students of Magicbullet network to develop 'gentle' cancer treatment

Medication that specifically targets cancer cells and delivers its active agent without harming healthy cells - this is what doctoral students of the Magicbullet network will be working on from mid-2015. Bielefeld University is coordinating the programme for the development of "gentle" cancer treatment.

19 Feb 2015

Nicotine metabolite supports learning, memory by amplifying action of primary chemical messenger

Nicotine's primary metabolite supports learning and memory by amplifying the action of a primary chemical messenger involved in both, researchers report.

19 Feb 2015

Psychemedics' revenue increases 4% to $6.8 million in fourth quarter 2014

Psychemedics Corporation today announced fourth quarter and year-end financial results for the period ended December 31, 2014. The Company also announced a quarterly dividend of $0.15 per share payable to shareholders of record as of February 23, 2015 to be paid on March 6, 2015. This will be the Company's 74th consecutive quarterly dividend.

11 Feb 2015

Study shows that drinking green tea before taking supplements may reduce toxicity risk

As high doses of green tea extract supplements for weight loss become more popular, potential liver toxicity becomes a concern. In the last decade, dozens of people have been diagnosed with the condition. However, drinking green tea in the weeks before taking supplements likely reduces risk, according to researchers in Penn State's College of Agricultural Sciences.

5 Feb 2015

Cell-penetrating nanoparticles can efficiently transport oligonucleotide drugs into cells

Therapeutic oligonucleotide analogs represent a new and promising family of drugs that act on nucleic acid targets such as RNA or DNA; however, their effectiveness has been limited due to difficulty crossing the cell membrane.

31 Jan 2015

New study may lead to novel drug target for treating lung cancer

A new study by University of Kentucky Markey Cancer Center researchers suggests that targeting a key enzyme and its associated metabolic programming may lead to novel drug development to treat lung cancer.

27 Jan 2015

Morphine after tonsillectomy may be life threatening for children

Treating post-operative pain with morphine can cause life-threatening respiratory problems in some children who have had their tonsils and/or adenoids removed, new research has found.

27 Jan 2015

INRS researchers to use new specialized equipment to study environmental equity, male infertility

With the acquisition of new specialized equipment, INRS researchers Philippe Apparicio, Géraldine Delbès, and Maritza Jaramillo and their teams will be able to advance knowledge and train highly qualified people in the fields of environmental equity, reproductive toxicology, and the treatment of infections. They received a total of over $1 million from the Quebec government and the John R. Evans Leaders Fund of the Canadian Foundation for Innovation.

22 Jan 2015

UChicago researchers awarded NIH grants to develop novel medications for sleep apnea, asthma

Two research teams based at the University of Chicago have received prestigious grants from the National Institutes of Health to develop novel medications to treat sleep apnea and asthma.

21 Jan 2015

New study finds no correlation between opioids administered in the ER and patient satisfaction scores

A new study co-authored by investigators at the University of Massachusetts Medical School found that there is no correlation between opioids administered in the emergency room setting and Press Ganey ED patient satisfaction scores, one of the most commonly used metrics for measuring patient satisfaction.

16 Jan 2015

Exposure to nanoparticles can play major role in development of cardiovascular diseases

Nanoparticles, extremely tiny particles measured in billionths of a meter, are increasingly everywhere, and especially in biomedical products. Their toxicity has been researched in general terms, but now a team of Israeli scientists has for the first time found that exposure nanoparticles (NPs) of silicon dioxide (SiO2) can play a major role in the development of cardiovascular diseases when the NP cross tissue and cellular barriers and also find their way into the circulatory system.

8 Jan 2015

More insight into influence of obesity on distribution, elimination of drugs needed, say experts

Doctors and pharmacists often do not take obesity into account when prescribing medication. For this, more insight into the influence of obesity on the distribution and elimination of drugs is of the utmost importance. This is emphasized by Catherijne Knibbe in the most recent issue of the Annual Review of Pharmacology and Toxicology.

7 Jan 2015

Palatin begins bremelanotide phase 3 study for treatment of female sexual dysfunction

Palatin Technologies, Inc., a biopharmaceutical company developing targeted, receptor-specific peptide therapeutics for the treatment of diseases with significant unmet medical needs and commercial potential, today announced that it has started its bremelanotide pivotal registration program.

29 Dec 2014

Methamphetamine use may increase Parkinson's disease risk

In addition to incurring serious dental problems, memory loss and other physical and mental issues, methamphetamine users are three times more at risk for getting Parkinson's disease than non-illicit drug users, new research from the University of Utah and Intermountain Healthcare shows.

17 Dec 2014

FL118 agent shows efficacy as personalized, targeted therapy for certain cancer tumors

A team led by Fengzhi Li, PhD, and Xinjiang Wang, PhD, of Roswell Park Cancer Institute has reported new findings regarding therapeutic targets of the novel anticancer agent FL118. Previous studies from these researchers have showed that FL118 induces cancer cell death, or apoptosis, by inhibiting expression of multiple cell-survival proteins (survivin, Mcl-1, XIAP or cIAP2).

15 Dec 2014

New study analyses prevalence of domestic violence against pregnant women

A new study analyses the violent behaviours exhibited towards pregnant women. While 21% of women suffer emotional violence during pregnancy, 3.6% encounter physical or sexual violence. Furthermore, 36.1% of those who reported physical violence claimed that it happened "very often" or "daily".

14 Dec 2014

Researchers develop new method to track movement of carcinogenic PAHs in the human body

Researchers for the first time have developed a method to track through the human body the movement of polycyclic aromatic hydrocarbons, or PAHs, as extraordinarily tiny amounts of these potential carcinogens are biologically processed and eliminated.

11 Dec 2014

Three IU researchers receive $2.1 million to develop computational biology models of liver toxicity

Three Indiana University professors have received $2.1 million to develop a computational model of acetaminophen-induced liver failure -- the leading cause of liver failure in the United States -- by using advanced microscopic and computational technologies that allow scientists to see into the liver of a living animal.

5 Dec 2014

Organovo, Yale collaborate to develop bioprinted tissues for surgical transplantation research

Organovo Holdings, Inc., a three-dimensional biology company focused on delivering breakthrough 3D bioprinting technology, and Yale School of Medicine, Department of Surgery have formed a collaboration to develop bioprinted tissues for surgical transplantation research, made possible by a generous gift from the Methuselah Foundation.

3 Dec 2014

Toxicology News and Research

Latest Toxicology News and Research

Palatin introduces clinical trial website in support of bremelanotide phase 3 study for FSD treatment

Doctoral students of Magicbullet network to develop 'gentle' cancer treatment

Nicotine metabolite supports learning, memory by amplifying action of primary chemical messenger

Psychemedics' revenue increases 4% to $6.8 million in fourth quarter 2014

Study shows that drinking green tea before taking supplements may reduce toxicity risk

Cell-penetrating nanoparticles can efficiently transport oligonucleotide drugs into cells

New study may lead to novel drug target for treating lung cancer

Morphine after tonsillectomy may be life threatening for children

INRS researchers to use new specialized equipment to study environmental equity, male infertility

UChicago researchers awarded NIH grants to develop novel medications for sleep apnea, asthma

New study finds no correlation between opioids administered in the ER and patient satisfaction scores

Exposure to nanoparticles can play major role in development of cardiovascular diseases

More insight into influence of obesity on distribution, elimination of drugs needed, say experts

Palatin begins bremelanotide phase 3 study for treatment of female sexual dysfunction

Methamphetamine use may increase Parkinson's disease risk

FL118 agent shows efficacy as personalized, targeted therapy for certain cancer tumors

New study analyses prevalence of domestic violence against pregnant women

Researchers develop new method to track movement of carcinogenic PAHs in the human body

Three IU researchers receive $2.1 million to develop computational biology models of liver toxicity

Organovo, Yale collaborate to develop bioprinted tissues for surgical transplantation research

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Toxicology News and Research

Latest Toxicology News and Research

Forensics And Toxicology eBook

Precision in every drop: Inside Hamilton’s syringe technology

Exploring the Future of Neuroscience Drug Discovery

Genomic conservation in Thailand's mangroves

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