Toxicology News and Research

Latest Toxicology News and Research

Emergency physicians to present research studies at Research Forum 2010

The risks associated with boarding admitted patients in the emergency department – including patient mortality – as well as proposed solutions will be key themes of Scientific Assembly, the annual meeting of the American College of Emergency Physicians. In addition, emergency physicians will present more than 450 research studies during 2010 Research Forum, the premier, annual scientific research event focused on the latest advances in the practice of emergency medicine.

14 Sep 2010

Metabolon receives patent for metabolic age analysis

Metabolon, Inc., leaders in global metabolomics, biomarker discovery and biochemical analysis, announced today the grant of US Patent 7,781,160 entitled "Biomarkers Related to Metabolic Age and Methods Using the Same". The USPTO awarded the patent to Metabolon on August 24, 2010. This is the 12th patent issued to Metabolon.

14 Sep 2010

InterMune's development program for pirfenidone, IPF to be presented at Annual Congress of ERS

InterMune, Inc. today announced that four oral presentations related to the company's development program for pirfenidone and idiopathic pulmonary fibrosis will be presented at the Annual Congress of the European Respiratory Society, to be held September 18-22 in Barcelona, Spain.

13 Sep 2010

Researchers develop KU-32 drug to prevent diabetic peripheral neuropathy

A drug developed at the University of Kansas has the potential to stop a debilitating condition of diabetes that often leads to pain in the extremities and even amputations, KU researchers have found.

13 Sep 2010

BPA detectable in saliva of children for up to three hours after completion of dental work

Researchers from Mount Sinai School of Medicine have found that bisphenol A (BPA) released from some plastic resins used in pediatric dentistry is detectable in the saliva after placement in children's mouths. BPA is a widely used synthetic chemical that has been associated with changes in behavior, prostate and urinary tract development, and early onset of puberty. The findings are published in the current issue of Pediatrics.

10 Sep 2010

ASNM to hold annual conference on nanomedicine

There is enormous excitement and expectation surrounding the multidisciplinary field of nanomedicine the science and technology of diagnosing, treating and preventing disease using nanotechnology. The American Society for Nanomedicine (ASNM) is holding its second annual conference on October 14-16, 2010 in the Washington, D.C. area, where some of the biggest stakeholders in this emerging technology operate and practice.

10 Sep 2010

PLX4032 trial shows high degree of selectivity to achieve tumor shrinkage

Plexxikon today announced publication of key data in this week's edition of Nature demonstrating that the high degree of selectivity of PLX4032 (RG7204) enables substantial RAF/MEK/ERK pathway inhibition, which may be necessary to achieve significant tumor shrinkage and clinical response in patients with BRAF mutant melanoma.

8 Sep 2010

NIH to launch study on Gulf oil spill health effects

The National Institutes of Health will launch a multi-year study this fall to look at the potential health effects from the oil spill in the Gulf region. The Gulf Worker Study, announced by NIH Director Francis S. Collins, M.D., Ph.D., in June, is in response to the largest oil spill in U.S. history, caused by the explosion of the Deepwater Horizon offshore drilling oil rig in the Gulf of Mexico. Dr. Collins pledged $10 million in NIH funding for the study's initial phases.

8 Sep 2010

Idenix Pharmaceuticals receives clinical hold order from FDA for IDX184, IDX320 programs

Idenix Pharmaceuticals, Inc., a biopharmaceutical company engaged in the discovery and development of drugs for the treatment of human viral diseases, today announced that the company received verbal notice on Friday, September 3, 2010 from the U.S. Food and Drug Administration (FDA) that the IDX184 and IDX320 programs have been placed on clinical hold.

7 Sep 2010

RIFM publishes special issue on safety assessment of unsaturated alcohols

The Research Institute for Fragrance Materials, Inc. (RIFM) has now published on the RIFM web site, in the Publications section, a special issue of Food and Chemical Toxicology, Volume 48, Supplement 3, on the RIFM Human Health Group Summary, A Safety Assessment of Non-cyclic Alcohols with Unsaturated Branched Chain when used as Fragrance Ingredients.

4 Sep 2010

UB symposium to discuss in silico molecular design, high-throughput screening to treat diseases

Twenty-first-century pharmaceutical breakthroughs require 21st-century drug discovery tools, such as computational or in silico molecular design and high-throughput screening of effective, new compounds. That's the theme of a University at Buffalo symposium to be held Sept. 11 on "Twenty-first Century Bioscience: In Silico Methods and High-Throughput Screening," which will feature a variety of cutting-edge advances in the field developed by researchers in Western New York and throughout the US.

3 Sep 2010

Researchers find hair cortisol level can assess chronic stress in heart attack

Researchers at The University of Western Ontario have provided the first direct evidence using a biological marker, to show chronic stress plays an important role in heart attacks.

3 Sep 2010

Ricerca Biosciences completes purification of an API under cGMP controls

Ricerca Biosciences, a uniquely integrated preclinical contract research organization (CRO) providing services to the biopharmaceutical industry, is pleased to announce the successful completion of the purification of an active pharmaceutical ingredient (API) under current good manufacturing practices (cGMP) controls.

27 Aug 2010

Researchers develop microneedles to deliver quantum dots for skin cancer treatment

Researchers from North Carolina State University have developed extremely small microneedles that can be used to deliver medically-relevant nanoscale dyes called quantum dots into skin - an advance that opens the door to new techniques for diagnosing and treating a variety of medical conditions, including skin cancer.

26 Aug 2010

Continuous boosting of natural painkiller shuts down brain cell receptor response

ERepeatedly boosting brain levels of one natural painkiller soon shuts down the brain cell receptors that respond to it, so that the painkilling effect is lost, according to a surprising new study led by Scripps Research Institute and Virginia Commonwealth University scientists. The study has important implications for drug development.

25 Aug 2010

Simulations Plus launches Version 7.0 of GastroPlus software for pharmaceutical industry

Simulations Plus, Inc.,a leading provider of simulation and modeling software for pharmaceutical discovery and development, has announced the launch of Version 7.0 of GastroPlus, the industry's gold standard software for the simulation of drug absorption, pharmacokinetics, and pharmacodynamics.

25 Aug 2010

Prenatal exposure to atrazine leads to prostate inflammation in male rats

A new study shows that male rats prenatally exposed to low doses of atrazine, a widely used herbicide, are more likely to develop prostate inflammation and to go through puberty later than non-exposed animals. The research adds to a growing body of literature on atrazine, an herbicide predominantly used to control weeds and grasses in crops such as corn and sugar cane. Atrazine and its byproducts are known to be relatively persistent in the environment, potentially finding their way into water supplies.

25 Aug 2010

NCF announces formal disease model for Chronic Fatigue Syndrome

The National CFIDS Foundation Inc., of Needham Mass, has announced its formal disease model for Chronic Fatigue Syndrome (CFS) also known as Chronic Fatigue Immune Dysfunction Syndrome (CFIDS) as well as Myalgic Encephalomyelitis (ME). According to the NCF, a subgroup of patients with CFS fit a unique disease profile based on a model for a radioactive toxin.

21 Aug 2010

Cyprotex launches new in vitro toxicology service

Cyprotex PLC, the preclinical ADME Tox services company, today announces the launch of its new in vitro toxicology service, branded as Cyprotox(R). Supporting the new service is an additional 90 square metres of laboratory space at Cyprotex's Macclesfield, UK facility housing the latest technology in multi-parametric automated fluorescent imaging and cellular analysis. This gives Cyprotex's Macclesfield site the same in vitro toxicology capabilities as those of Apredica (Watertown, MA, USA), which Cyprotex acquired on 6 August 2010.

From Thermo Fisher Scientific Inc. 20 Aug 2010

Dr. Hartung receives Agilent Thought Leader Award for developmental neurotoxicity research

Agilent Technologies Inc. and the Agilent Foundation today announced that Dr. Thomas Hartung has received an Agilent Thought Leader Award in support of his research for the use of toxicity pathways to predict developmental neurotoxicity. This work could help identify possible contributions of chemicals to disorders such as autism and attention hyperactivity disorders.

19 Aug 2010

Toxicology News and Research

Latest Toxicology News and Research

Emergency physicians to present research studies at Research Forum 2010

Metabolon receives patent for metabolic age analysis

InterMune's development program for pirfenidone, IPF to be presented at Annual Congress of ERS

Researchers develop KU-32 drug to prevent diabetic peripheral neuropathy

BPA detectable in saliva of children for up to three hours after completion of dental work

ASNM to hold annual conference on nanomedicine

PLX4032 trial shows high degree of selectivity to achieve tumor shrinkage

NIH to launch study on Gulf oil spill health effects

Idenix Pharmaceuticals receives clinical hold order from FDA for IDX184, IDX320 programs

RIFM publishes special issue on safety assessment of unsaturated alcohols

UB symposium to discuss in silico molecular design, high-throughput screening to treat diseases

Researchers find hair cortisol level can assess chronic stress in heart attack

Ricerca Biosciences completes purification of an API under cGMP controls

Researchers develop microneedles to deliver quantum dots for skin cancer treatment

Continuous boosting of natural painkiller shuts down brain cell receptor response

Simulations Plus launches Version 7.0 of GastroPlus software for pharmaceutical industry

Prenatal exposure to atrazine leads to prostate inflammation in male rats

NCF announces formal disease model for Chronic Fatigue Syndrome

Cyprotex launches new in vitro toxicology service

Dr. Hartung receives Agilent Thought Leader Award for developmental neurotoxicity research

Forensics And Toxicology eBook

Precision in every drop: Inside Hamilton’s syringe technology

Exploring the Future of Neuroscience Drug Discovery

Genomic conservation in Thailand's mangroves

Toxicology News and Research

Latest Toxicology News and Research

Forensics And Toxicology eBook

Precision in every drop: Inside Hamilton’s syringe technology

Exploring the Future of Neuroscience Drug Discovery

Genomic conservation in Thailand's mangroves

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