Tuberculosis News and Research

Latest Tuberculosis News and Research

Study on ustekinumab for treatment of psoriatic arthritis published

A group of patients suffering from potentially debilitating psoriatic arthritis showed significant and prolonged improvement after treatment with ustekinumab, according to data from a randomized, double-blind, placebo-controlled study in patients with moderate to severe psoriatic arthritis (PsA).

11 Feb 2009

Long-sought protein structure may help reveal how ‘gene switch’ works

The bacterium behind one of mankind's deadliest scourges, tuberculosis, is helping researchers at the Commerce Department's National Institute of Standards and Technology (NIST) and the Department of Energy's Brookhaven National Laboratory (BNL) move closer to answering the decades-old question of what controls the switching on and off of genes that carry out all of life's functions.

10 Feb 2009

Long-sought protein structure may help reveal how 'gene switch' works

8 Feb 2009

Robot scientist promises to dig up new drugs

A robot scientist that can make informed guesses about how effective different chemical compounds will be at fighting different diseases could revolutionise the pharmaceutical industry by developing more effective treatments more cheaply and quickly than current methods.

3 Feb 2009

Century old drug clofazimine shows potential for multiple sclerosis

A century-old drug that failed in its original intent to treat tuberculosis but has worked well as an antileprosy medicine now holds new promise as a potential therapy for multiple sclerosis and other autoimmune diseases.

2 Feb 2009

New compound shows potential as tuberculosis drug

Rajesh Gokhale has created a compound in his lab in India that stops tuberculosis in its tracks.

2 Feb 2009

Substance use common among patients with tuberculosis

About one in five U.S. tuberculosis patients reports abusing alcohol or using illicit drugs, and those who do appear more contagious and difficult to treat, according to a report in the January 26 issue of Archives of Internal Medicine.

27 Jan 2009

Waging war on tropical diseases may be key to U.S. foreign policy

Stating that neglected tropical diseases (NTDs) not only promote poverty but also destabilize communities, former Health and Human Services Secretary Tommy Thompson and Sabin Vaccine Institute President Peter Hotez call upon the public-health and foreign-policy communities to embrace medical diplomacy and NTD control as a means to combat terrorism in an article published January 27 in the open-access journal PLoS Neglected Tropical Diseases.

27 Jan 2009

New treatment for latent form of tuberculosis

Patients who are infected with the latent form of tuberculosis (TB) show no symptoms and are not contagious, yet they pose the biggest challenge when it comes to controlling the disease.

23 Jan 2009

Australian discovers gene for deadly Kawasaki disease

An Australian researcher has identified genes which could make some children more susceptible to the deadly Kawasaki disease - an inflammatory condition in young children that can damage blood vessels.

12 Jan 2009

Tuberculosis commandeers body's defenses to gain foothold

Tuberculosis bacteria can commandeer the body's defenses in the early stages of infection and redirect them for their own offensive strategies, according to results reported in the scientific journal, Cell.

9 Jan 2009

New nasal spray vaccine shown to be effective against botulism

A preclinical study found a new nasal spray vaccine to provide complete protection against a major botulism toxin, according to a study published today in the Nature journal Gene Therapy .

8 Jan 2009

New avenue for TB therapy

Masses of immune cells that form as a hallmark of tuberculosis (TB) have long been thought to be the body's way of trying to protect itself by literally walling off the bacteria.

8 Jan 2009

Sequella, Inc. drug compound SQ109 selected for phase 1B clinical trial program

Sequella, Inc., a clinical-stage biopharmaceutical company focused on diseases of epidemic potential, announced today that SQ109, its lead drug candidate for the treatment of tuberculosis (TB), was the first drug approved for evaluation in a newly awarded clinical program contract to Dynport Vaccine Company LLC and Quintiles Transnational.

6 Jan 2009

May hepatic granulomas be part of the histological spectrum of chronic hepatitis C?

While older large series of patients with hepatic granulomas have found sarcoidosis and tuberculosis to be the most common causes of hepatic granulomas, recent works have noted some patients with chronic hepatic C and hepatic granulomas and no other obvious associations.

30 Dec 2008

Blocking mechanism found for antibiotic resistance in bacteria

It's as simple as A, T, G, C. Northwestern University scientists have exploited the Watson-Crick base pairing of DNA to provide a defensive tool that could be used to fight the spread of antibiotic resistance in bacteria -- one of the world's most pressing public health problems.

18 Dec 2008

Blocking immune receptor molecule improves response to HIV-like virus, prolongs survival in monkeys

By blocking PD-1 (programmed death-1), an immune receptor molecule known to inhibit the immune response to chronic viral infections, scientists have safely and significantly reduced the plasma viral load and also prolonged survival of rhesus macaque monkeys severely infected with simian immunodeficiency virus (SIV), the nonhuman primate version of human immunodeficiency virus (HIV).

10 Dec 2008

Accelerating progress in the development of vaccines

This week the Elsevier Journal Vaccine, the most comprehensive and pre-eminent journal for those interested in vaccines and vaccination, organized the 2nd Vaccine Global Congress in Boston MA, USA.

10 Dec 2008

Drug-resistant tuberculosis rife in China

Levels of drug-resistant tuberculosis (TB) in China are nearly twice the global average. Nationwide research published in the open access journal BMC Infectious Diseases has shown that almost 10% of Chinese TB cases are resistant to the most effective first-line drugs.

10 Dec 2008

As many as 300 children could be at risk of TB from hospital doctor

After a doctor at Adelaide's Women's and Children's Hospital tested positive for tuberculosis (TB), authorities say as many as 300 babies have been identified who may have come into contact with the doctor and could be at risk.

10 Dec 2008