Tuberculosis News and Research

Latest Tuberculosis News and Research

Research breakthrough in treatment of TB and MDR-TB

FASgen Inc.'s compound, FAS20013, has emerged from an intense multi-year program of pre-clinical studies that clearly validate its potential as an ideal new drug for the treatment of tuberculosis and MDR-TB, the disease caused by organisms that are resistant to the drugs now commonly used to treat TB. Initial clinical trials in both TB and MDR-TB are scheduled for later this year.

12 Jan 2005

Key genetic factor determines HIV/AIDS risk

People with more copies of a gene that helps to fight HIV are less likely to become infected with the virus or to develop AIDS than those of the same geographical ancestry, such as European Americans, who have fewer copies of the gene, according to a study funded by the National Institute of Allergy and Infectious Diseases (NIAID).

10 Jan 2005

Novel treatment promises to be an effective cure for tuberculosis

Researchers in Belgium have uncovered a novel treatment that promises to be an effective cure for tuberculosis (TB). The respiratory disease has been experiencing a major global comeback due to the emergence of resistant strains of the bacteria that causes it and the spread of AIDS.

9 Jan 2005

Diagnosis of tuberculosis in young children can be confirmed by a straightforward sputum test

Diagnosis of tuberculosis is difficult in infants and young children and can be complicated by HIV infection. Heather Zar (School of Child and Adolescent Health, University of Cape Town, South Africa) and colleagues studied 250 children aged 1 month to 5 years who were admitted for suspected pulmonary tuberculosis in Cape Town. Sputum induction and gastric lavage were done on three consecutive days according to a standard procedure.

7 Jan 2005

PAHO dispels myths about the handling and the effects of mass casualties

The Pan American Health Organization (PAHO) has published a new manual that dispels myths about the handling and the effects of mass casualties following a natural disaster, such as the December 26 earthquake and tsunami in South Asia.

5 Jan 2005

Vaccine Treatment and Evaluation Units (VTEUs) supply the nurse power necessary to beat back or altogether prevent infectious disease

Flu. Smallpox. Anthrax. Whooping cough. The words represent a veritable murderers' row of infectious agents whose death toll runs in the millions.

23 Dec 2004

The burgeoning Indian AIDS epidemic

India, home to one-sixth of the human race, has an AIDS epidemic. Five million Indians are living with HIV infection. The stakes are high; the government is racing against time.

21 Dec 2004

Study on first new potential drug for tuberculosis in 40 years

454 Life Sciences, a majority-owned subsidiary of CuraGen Corporation, announced today that its proprietary whole genome sequencing technology was used by scientists at Johnson & Johnson Pharmaceutical Research & Development L.L.C. (J&JPRD) to help understand the basis of tuberculosis drug resistance.

20 Dec 2004

Risk of tuberculosis infection doubles within one year of HIV infection

Scientists previously assumed that there was no increase in tuberculosis risk within the first few years of HIV infection. Pam Sonnenberg of the London School of Hygiene and Tropical Medicine and colleagues were therefore surprised by the results of their research on the two infections, which they conducted in South African gold miners.

20 Dec 2004

Scientists have identified a novel anti-tuberculosis (TB) compound

Scientists at Johnson & Johnson Pharmaceutical Research and Development have identified a novel anti-tuberculosis (TB) compound that works better and faster than the current standard of care in mouse models of TB infection.

14 Dec 2004

African health care systems: what went wrong?

The last century witnessed unparalleled improvements in the health indicators of many countries in the African Region, particularly reductions in child mortality.

8 Dec 2004

Trimming fat overcomes one of the major obstacles to drug design

Biochemists at Ohio State University and their colleagues have overcome one of the major obstacles to drug design, by trimming some of the fat from a molecular sponge that scientists use to study proteins.

8 Dec 2004

Electrochemical DNA chip that is able to detect DNA at very low concentrations

Toshiba Corporation has announced the development of a highly sensitive electrochemical DNA chip that is able to detect DNA at very low concentrations, a capability that will support advances in gene detection and analysis for individual treatment regimes, and the monitoring of healthy individuals for any predisposition to certain diseases.

6 Dec 2004

Oral administration of saline spray may stop spread of influenza, tuberculosis, and SARS

Some individuals exhale many more pathogen-laden droplets than others in the course of ordinary breathing, scientists have found, but oral administration of a safe saline spray every six hours might slash exhalation of germs in this group by an average 72 percent.

29 Nov 2004

Rifampicin can prevent the formation of protein fibrils associated with Parkinson's disease

Researchers at the University of California, Santa Cruz, have shown that rifampicin, an antibiotic used to treat leprosy and tuberculosis, can prevent the formation of protein fibrils associated with the death of brain cells in people with Parkinson's disease. The drug also dissolved existing fibrils in laboratory tests.

29 Nov 2004

Moldova making progress in fight against HIV/AIDS and tuberculosis

Moldova’s early actions to fight HIV/AIDS and tuberculosis are slowing the rise of the country’s dual tuberculosis and AIDS epidemics, the World Bank reports.

29 Nov 2004

Crystals may help to revolutionise drug discovery

A groundbreaking technique developed at The University of Manchester, which uses crystals to map ‘invisible’ parts of molecules, is set to revolutionise drug discovery.

From The University of Manchester 24 Nov 2004

Biotoxin from puffer fish may provide treatment for opioid withdrawal

On November 10, 2004 investigators involved in a Phase IIa clinical trial of the novel biotoxin Tetrodotoxin (TTX) for the treatment of opioid withdrawal enrolled their first participants.

18 Nov 2004

All patients in study clear parasite that causes African sleeping sickness

Immtech International has announced that all 30 patients participating in the concluded Phase IIb extended dose regimen arm of its clinical trial of DB289 for treating African sleeping sickness cleared the parasite that causes African sleeping sickness within the treatment period, with no significant adverse results reported.

11 Nov 2004

D-cycloserine (DCS), used in concert with psychotherapy, is an effective treatment for some anxiety-related disorders

A tuberculosis drug called D-cycloserine (DCS), used in concert with psychotherapy, is an effective treatment for some anxiety-related disorders, according to research by scientists at Emory University School of Medicine and the Center for Behavioral Neuroscience (CBN).

8 Nov 2004