Vesicoureteral Reflux

The retrograde (i.e. backward) flow of urine from the urinary bladder into the ureters is medically referred to as vesicoureteral reflux (VUR).

Vesicoureteral Reflux (Primary and Secondary)

The retrograde (i.e. backward) flow of urine from the urinary bladder into the ureters is medically referred to as vesicoureteral reflux (VUR).

Vesicoureteral Reflux Research

Voiding Cystourethrogram

Can Vesicoureteral Reflux be Inherited?

How is Vesicoureteral Reflux Diagnosed?

Vesicoureteral Reflux Epidemiology

Vesicoureteral Reflux Symptoms

Monitoring Children with Vesicoureteral Reflux

Vesicoureteral Reflux Management and Treatment

International Classification of Vesicoureteral Reflux

Latest Vesicoureteral Reflux News and Research

Researchers confirm that cranberry extract helps fight UTIs in breastfed children under age one

Researchers from the universities of Granada (Spain) and Kvopio (Finland) have confirmed that cranberry extract helps fighting urinary tract infections (UTIs) in breastfed babies under one year of age.

18 Jan 2016

Continuous antibiotics for children with antenatal hydronephrosis not necessary, study finds

Up to 5 percent of all prenatal ultrasounds uncover antenatal hydronephrosis, or enlarged kidneys, the most commonly detected prenatal abnormality in the United States. Many children with this abnormality are treated continually with preventive antibiotics for the first few years of life with the hopes of preventing the condition's associated urinary tract infections.

25 Jul 2014

Research may have "major implications" for treatment of urinary tract infections in children

A major new pediatric research study led by a Wayne State University researcher, funded by the National Institute of Diabetes and Digestive and Kidney Diseases of the National Institutes of Health (NIH) and published this week in the New England Journal of Medicine (NEJM), has "major implications" for the treatment of urinary tract infections (UTIs) in millions of American children.

8 May 2014

Long-term use of drug combination reduces risk of recurrent urinary tract infection in children

Long-term use of a drug combination reduces the risk of recurrent urinary tract infection by up to 80 percent in children with the urinary condition vesicoureteral reflux compared to placebo, according to research funded by the National Institutes of Health.

5 May 2014

Enterocystoplasty: A good surgical option for children with genitourinary abnormalities

Enterocystoplasty is a good surgical option with a low rate of severe complications in the treatment of children who were born with developmental abnormalities of the genitourinary system, according to the new study conducted by a group of Portuguese urologists.

30 Oct 2013

Risk factors identified for renal abnormality in vesicoureteral reflux

Researchers have identified the main risk factors for renal functional abnormalities in children with high-grade vesicoureteral reflux.

4 Feb 2013

Scars mark hypertension risk in vesicoureteral reflux

Renal scarring associated with vesicoureteral reflux is a significant risk factor for developing hypertension, shows a study of pediatric patients.

21 Nov 2012

Salix first quarter total product revenue increases 62% to $171.1M

Salix Pharmaceuticals, Ltd. today announced financial and operating results for the first quarter ended March 31, 2012 and other business updates.

8 May 2012

Salix to acquire Oceana Therapeutics

Oceana Therapeutics LLC, a privately owned global company focused on commercializing best-in-class specialty therapeutics, today announced it has entered into a definitive agreement for the sale of its operating subsidiary, Oceana Therapeutics, Inc. to Salix Pharmaceuticals, Ltd. of Raleigh, NC.

9 Nov 2011

Salix enters definitive agreement to acquire Oceana Therapeutics

Salix Pharmaceuticals, Ltd. and Oceana Therapeutics, LLC today announced that they have entered into a definitive agreement whereby Salix will acquire all of the outstanding stock of Oceana Therapeutics, Inc., a privately-held global provider of gastroenterology and urology therapeutics, for $300 million in cash.

8 Nov 2011

Pediatric urology research papers published in two Elsevier journals

The first World Congress of Pediatric Urology was held in San Francisco in May 2010, bringing together the largest and most successful international congregation of pediatric urologists ever assembled. As part of a collaborative effort, The Journal of Urology and the Journal of Pediatric Urology have together published the landmark papers presented at this meeting.

2 May 2011

Vesicoureteral reflux more common among girls

Children with vesicoureteral reflux (VUR), in which urine flows backwards into the kidneys from the bladder, have been treated in the past with surgery or antibiotic therapy.

21 May 2010

Researchers develop new mouse model of VUR to study chronic kidney disease in children

Kidney damage associated with chronic reflux is the fourth leading cause of chronic kidney disease and is the most common cause of severe hypertension in children. Doctors and researchers at Nationwide Children's Hospital have developed a new mouse model of vesicoureteral reflux, a common childhood condition that can lead to chronic kidney disease in children.

7 Apr 2010

New injection device for endoscopic treatment of pediatric vesicoureteral reflux

A new injection device for the endoscopic treatment of vesicoureteral reflux) offers urologists greater control, precision and accuracy for treating a condition of the urinary tract that predominantly affects infants and young children. An alternative to corrective surgery, the Injekt VUR Injection Needle marks an advancement in fast and minimally-invasive endoscopic treatment.

24 Mar 2010

Prophylactic antibiotics for children with UTI not associated with reduced risk of recurrence

The use of prophylactic antibiotics, which involves daily administration of antibiotics to children after an initial urinary tract infection, is not associated with reduced risk of recurrent urinary tract infections, but is associated with an increased risk of resistant infections, according to a study in the July 11 issue of JAMA.

11 Jul 2007

Top 10 diseases by cost

Bladder, prostate and other urinary tract diseases cost Americans nearly $11 billion a year, according to a new report from the National Institutes of Health.

2 May 2007

Renal transplantation in 1-5 year olds

Garcia, et al reported their experience with renal transplantation in 38 children (40 transplant), ages 1-5 years over a 16 year period.

26 Apr 2007

Uroplasty receives FDA approvable letter for treatment of female stress urinary incontinence

Uroplasty, Inc. has announced that it has received an approvable letter from the U.S. Food and Drug Administration (FDA) relating to its pre-market approval (PMA) application for Macroplastique Implants for the treatment of female stress urinary incontinence (SUI).

14 Sep 2006

Permanent renal parenchymal defects after febrile UTI are closely associated with vesicoureteric reflux

This study from Italy investigated the association of vesicoureteral reflux (VUR) and renal scarring.

5 Sep 2006

MR cystography accurate and safe for vesicoureteral reflux screening

MR cystography provides excellent anatomic detail of the urinary system and is a potential screening examination for vesicoureteral reflux (VUR), according to a new study by researchers from Changi General Hospital in Singapore and the University of California, San Francisco.

3 May 2006