Dynastat

The full CMI on the next page has more details. If you are worried about using this medicine, speak to your doctor or pharmacist.

Dynastat contains the active ingredient parecoxib sodium. Dynastat is used to relieve pain and reduce swelling and soreness which may occur after surgery. For more information, see Section 1. Why am I being treated with Dynastat? in the full CMI.

You must not be given Dynastat if you: have ever had an allergic reaction to parecoxib or any ingredients listed at the end of the CMI, take other medicines to relieve pain, reduce swelling and soreness or sulfonamides antibiotics; are about to have heart or blood vessel surgery, have had heart or other blood vessel disease, stroke, severe liver problems or in the third trimester of pregnancy or are breastfeeding. Tell your doctor if you have or ever had kidney or liver problems, heart diseases, other blood vessel diseases or taking medicines for these conditions, stroke, diabetes, high cholesterol, high or low blood pressure, water retention or taking “water” tablets, dehydrated, asthma, blood clots or taking medicine for blood clots, swelling, blistering, peeling, itching, reddening or some other skin problems after taking similar medicines, stomach ulcers or bloody or black stools, smoke, have a fever or an infection. For more information, see Section 2. What should I know before I treatment with Dynastat? in the full CMI.

Some medicines may interfere with Dynastat and affect how it works.
A list of these medicines is in Section 3. What if I am taking other medicines? in the full CMI.

Dynastat is given by a doctor or nurse. Your doctor will decide how much Dynastat you will need. More instructions can be found in Section 4. How Dynastat will be given to me? in the full CMI.

For more information, see Section 5. What should I know during treatment with Dynastat? in the full CMI.

Side effects: allergic reaction, e.g., wheezing, swollen face, lips, mouth, tongue or throat which may cause difficulty in swallowing or breathing; skin rash, swelling/blistering/peeling; bruises; red, purple blotches; blisters/bleeding lips, eyes, mouth, nose, genitals; swollen armpit, neck or limbs; injection site pain/reaction; fever; chills; delayed wound healing; wound discharges; pain after tooth extraction; yellow skin/eyes; back, joint pain; weak muscle; earache; tiredness; pale looking skin; slow or irregular heartbeat; low/high blood pressure; dizziness; fainting; shortness of breath; chest, neck or shoulder pain; swollen, sore leg veins; severe, persistent headache, stiff neck, light sensitivity; weight gain; appetite loss; diarrhoea; unusual stomach sounds; severe stomach pain; sore throat; vomiting; bloody/black stool; heartburn; constipation; wind, bloating; dry mouth, feeling thirsty; urinate often; pass less urine; trouble sleeping; irritability; agitation; skin becomes numb or painful to touch; increased sweating; liver, kidney or heart problems; and blood sugar, calcium or potassium changes. For more information, including what to do if you have any side effects, see Section 6. Are there any side effects? in the full CMI.

Active ingredient(s): parecoxib sodium

This leaflet provides important information about using Dynastat. You should also speak to your doctor or pharmacist if you would like further information or if you have any concerns or questions about using Dynastat.

Where to find information in this leaflet:

Dynastat contains the active ingredient parecoxib sodium. Dynastat is a type of non-steroidal anti-inflammatory drug (NSAID) and belongs to a group of medicines called Coxibs. Dynastat is used to relieve pain and reduce swelling and soreness, which may occur after surgery.

Ask your doctor if you have any questions about why this medicine has been prescribed for you.

Your doctor may have prescribed it for another reason.

During treatment, you may be at risk of developing certain side effects. It is important you understand these risks and how to monitor for them. See additional information under Section 6. Are there any side effects?

Tell your doctor and nurse if you are pregnant or intend to become pregnant.

You should not be treated with Dynastat if you are in the third trimester of your pregnancy.

Use of Dynastat during the first two trimesters of your pregnancy is not recommended as it may affect your developing baby. It may also affect labour. Your doctor will discuss with you the benefits and risks of using it.

Related medicines, NSAIDs, have been associated with reversible infertility in some women.

Use of NSAIDs in early pregnancy can increase the risk of spontaneous abortion and may affect your developing baby.

Use of NSAIDs in the second or third trimester of your pregnancy may cause kidney problems in your developing baby.

Tell your doctor and nurse if you are breastfeeding or intend to breastfeed.

You should not be treated with Dynastat if you are breastfeeding.

Dynastat passes into breast milk, therefore, you need to stop breastfeeding during treatment with Dynastat.

There is not enough information to recommend the use of this medicine in children.

Tell your doctor or pharmacist if you are taking any other medicines, including any medicines, vitamins or supplements that you buy without a prescription from your pharmacy, supermarket or health food shop.

Some medicines may interfere with Dynastat and affect how it works. These include medicines for:

Check with your doctor or pharmacist if you are not sure about what medicines, vitamins or supplements you are taking and if these affect Dynastat.

Dynastat will be given to you in the hospital. Your doctor will decide how much Dynastat you need. It may depend on whether you have liver or kidney problems, your age, weight or other medicines you may be taking.

As Dynastat is most likely to be given to you in hospital under the supervision of your doctor, it is very unlikely that you will receive an overdose. However, if you experience any side effects tell your doctor or nurse immediately.

If you are given too much Dynastat, you may feel tired, drowsy, feel sick, have stomach pains or other abdominal problems.

If you are concerned that you may have been given too much Dynastat, you may need urgent medical attention.

You should immediately:

You should do this even if there are no signs of discomfort or poisoning.

Tell your doctor if you:

Do not take any other medication unless your doctor is aware of it.

Do not withhold your medical history including current medicines or supplements used from your doctor.

Be careful before you drive or use any machines or tools until you know how Dynastat affects you.

This medicine may cause dizziness or light-headedness in some people. If you have any of these symptoms, do not drive, operate machinery or do anything else that could be dangerous.

Tell your doctor or nurse if you drink alcohol.

Dynastat is stored in a hospital and it is responsible for storing and disposing of any unused product correctly.

All medicines can have side effects. If you do experience any side effects, most of them are minor and temporary. However, some side effects may need medical attention.

See the information below and, if you need to, ask your doctor or pharmacist if you have any further questions about side effects.

Tell your doctor or pharmacist if you notice anything else that may be making you feel unwell.

Other side effects not listed here may occur in some people.

After you have received medical advice for any side effects you experience, you can report side effects to the Therapeutic Goods Administration online at www.tga.gov.au/reporting-problems . By reporting side effects, you can help provide more information on the safety of this medicine.

Always make sure you speak to your doctor or pharmacist before you decide to stop taking any of your medicines.

This medicine is only available with a doctor's prescription.

Do not take this medicine if you are allergic to any of these ingredients.

Dynastat is a white to off-white powder. When diluted, Dynastat is a clear and colourless solution.

Dynastat 40 mg powder for injection - AUST R 82525.

Pfizer Australia Pty Ltd

Sydney NSW.

Toll Free Number: 1800 675 229.

www.pfizermedinfo.com.au .

This leaflet was prepared in December 2024.

® Registered trademark.