Consumer Medicine Information (CMI) summary
The
full CMI on the next page has more details. If you are worried about using this medicine,
speak to your doctor or pharmacist.
1. Why am I being given Targocid?
Targocid contains the active ingredient teicoplanin. Targocid injection is an antibiotic.
It is used to kill bacteria responsible for infections which can occur in your blood,
bones or joints. For more information, see Section
1. Why am I being given Targocid? in the full CMI.
2. What should I know before I am given Targocid?
Do not use if you have ever had an allergic reaction to Targocid or any of the ingredients
listed at the end of the CMI.
Talk to your doctor if you have any other medical conditions, take any other medicines,
are pregnant or plan to become pregnant, or are breastfeeding or planning to breastfeed.
For more information, see Section
2. What should I know before I am given Targocid? in the full CMI. What if I am taking other medicines?
3. What if I am taking other medicines?
4. How will I be given Targocid?
Targocid injection should be prepared and administered by a qualified health professional
(doctor, pharmacist or nurse). More instructions can be found in Section
4. How will I be given Targocid? in the full CMI.
5. What should I know while being given Targocid?
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Things you should do
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Call your doctor straight away if you notice any symptoms of serious skin reactions,
including blistering of your skin, mouth, eyes or genitals, a red scaly widespread
rash and blisters accompanied by a fever, or flu-like symptoms and a rash on your
face and body with a fever.
Remind any doctor, dentist or pharmacist that you visit that you are being given Targocid.
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Things you should not do
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Do not receive more than the recommended dose unless your doctor or pharmacist tells
you to.
Do not stop receiving Targocid because you are feeling better, unless advised by your
doctor or
pharmacist.
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Driving or using machines
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Be careful driving or operating machinery until you know how Targocid affects you.
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Looking after your medicine
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Targocid is stored in the pharmacy or on the ward.
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6. Are there any side effects?
There are a number of side effects associated with this medicine. Not all of these
side effects are listed here. It is important to be aware of them so that you can
identify any symptoms if they occur (see Section
6. Are there any side effects? in the full CMI for more details). Mild side effects include local pain and redness
at the injection site, rash, dizziness, nausea, headache and stiffness. Very serious
side effects which may indicate an allergic reaction include swelling of the face,
lips, mouth or throat, which may cause difficulty in swallowing or breathing, and
hives or welts on the skin. Other very serious side effects include blistering of
your skin, mouth, eyes or genitals, a red scaly widespread rash with bumps under the
skin and blisters accompanied by a fever, flu-like symptoms and a rash on your face
followed by an extended rash with a fever, increased levels of liver enzymes seen
in blood tests and an increase in a type of white blood cell (eosinophilia) and enlarged
lymph nodes, and kidney problems (shown in tests).
Active ingredient:
teicoplanin
Full Consumer Medicine Information (CMI)
This leaflet provides important information about using Targocid. You should also speak to your doctor or pharmacist if you would like further information
or if you have any concerns or questions about using Targocid.
Where to find information in this leaflet:
1. Why am I using Targocid?
1. Why am I being given Targocid?
Targocid contains the active ingredient teicoplanin. Targocid is an antibiotic. It is used to kill bacteria responsible for infections
which can occur in your blood, bones or joints.
Targocid is generally used when the bacteria causing the infection are not satisfactorily
eliminated by other antibiotics (e.g. penicillin), or when patients may be allergic
to other antibiotics.
2. What should I know before I am given Targocid?
Warnings
Do not receive Targocid if:
you are allergic to Targocid, or any of the ingredients listed at the end of this
leaflet. Always check the ingredients to make sure you can use this medicine.
Check with your doctor if you:
have or have had any other medical conditions, especially kidney problems or liver
problems
take any medicines for any other condition
have allergies to any other medicines, including to any other antibiotic (especially
an antibiotic called vancomycin, also known as Vancocin®), or any other substances, such as foods, preservatives or dyes
plan to have surgery
During treatment, you may be at risk of developing certain side effects. It is important
you understand these risks and how to monitor for them. See additional information
under Section
6. Are there any side effects?
Pregnancy and breastfeeding
Do not receive Targocid if you are pregnant or intend to become pregnant. Targocid is not recommended to be used during pregnancy.
Do not receive Targocid if you are breastfeeding or planning to breastfeed. It is not known whether Targocid passes into breast milk.
3. What if I am taking other medicines?
Tell your doctor or pharmacist if you are taking any other medicines, including any
that you buy without a prescription from your pharmacy, supermarket or health food
store.
Some medicines may interfere with Targocid and affect how it works. These include:
aminoglycoside antibiotics, medicine used to treat bacterial infections
amphotericin B (amphotericin), medicine used to treat fungal infections
ciclosporin, medicine used to help control your body's immune system
cisplatin, a medicine used in the treatment of some cancers
furosemide (frusemide), a medicine used to remove excess fluid in the body
etacrynic acid, a medicine used to help the kidneys get rid of salt and water
Check with your doctor of pharmacist if you are not sure about what medicines, vitamins
or supplements you are taking and if these affect Targocid.
4. How will I be given Targocid?
How much you will be given
On the first day of treatment most patients generally receive two doses of Targocid,
12 hours apart
During the following days, most patients receive ONE dose each day
After the first day, the daily dose varies between 6 mg and 12 mg for each kilogram
you weigh, depending on what type of infection you have. An adult of normal weight
(around 70 kg) would therefore receive a single daily dose of between 400 mg and 800
mg
Patients with kidney problems may need lower doses (or doses less often) than other
patients. Your doctor can calculate how much Targocid you require if you have kidney
problems.
If you have an infection in your blood, you will probably need to receive a daily
injection of Targocid for 2 to 4 weeks. If you have an infection in any bones or joints,
you may require a daily injection of Targocid for 3 to 6 weeks.
Follow the instructions provided and continue to receive Targocid for as long as prescribed
by your doctor.
How it is given
Targocid injection should be prepared and administered by a qualified health professional
(doctor, pharmacist or nurse).
The vial of Targocid powder should be mixed carefully with the sterile water, which
is included in the pack, to form a clear solution.
The solution may be injected into a vein directly over about 5 minutes, or it may
be mixed with other sterile solutions and delivered into a vein from a 'drip' bottle
or bag over about 30 minutes.
Targocid solution may also be injected directly into a muscle.
If you receive too much Targocid
As Targocid is given to you under the supervision of your doctor, it is very unlikely
that you will receive too much. However, if you think you have received too much,
or if you experience any unexpected or worrying side effects, you may need urgent
medical attention.
You should immediately:
Phone the Poisons Information Centre (by calling 13 11 26 in Australia or 0800 764 766 in New Zealand), or
Contact your doctor, or
Go to the Emergency Department at your nearest hospital.
You should do this even if there are no signs of discomfort or poisoning.
5. What should I know while using Targocid?
During treatment you may have tests to check your blood, your kidneys, your liver
and/or your hearing. This is more likely if your treatment will last for a long time,
you need to be treated with high doses, you have a kidney problem, you are taking
or may take other medicines that may affect your nervous system, kidneys or hearing.
Things you should do
Remind any doctor, dentist or pharmacist that you visit that you are being given Targocid.
If you plan to have surgery that needs a general anaesthetic, tell your doctor or
dentist that you are being given Targocid.
If you become pregnant while you are being given Targocid, stop receiving it and tell
your doctor or pharmacist immediately.
Call your doctor straight away if you notice:
blistering of the skin, mouth, eyes or genitals, which may be symptoms of severe skin
reactions called 'Stevens-Johnson Syndrome', or 'Toxic Epidermal Necrolysis', or
a red scaly widespread rash with bumps under the skin and blisters accompanied by
a fever, which may be symptoms of a severe skin reaction called 'Acute Generalised
Exanthematous Pustulosis', or
flu-like symptoms and a rash on your face, then an extended rash with a high temperature,
which may be symptoms of a condition called 'Drug Reaction with Eosinophilia and Systemic
Symptoms'.
Things you should not do
Do not receive more than the recommended dose unless your doctor or pharmacist tells
you to.
Do not use this medicine to treat any other complaints unless your doctor or pharmacist
tells you to.
Do not stop receiving Targocid because you are feeling better, unless advised by your
doctor or pharmacist.
Driving or using machines
Be careful driving or operating machinery until you know how Targocid affects you.
Looking after your medicine
Targocid is stored in the pharmacy or on the ward.
6. Are there any side effects?
All medicines have some unwanted side effects. If you do experience any side effects,
most of them are minor and temporary. However, some side effects may need medical
attention. See the information below and, if you need to, ask your doctor or pharmacist
if you have any further questions about side effects.
Less serious side effects
Serious side effects
Very serious side effects
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Very serious side effects
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What to do
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Allergic reaction-related:
swelling of the face, lips, mouth or throat, which may cause difficulty in swallowing
or breathing
hives or welts on your skin
Skin reactions:
blistering of the skin, mouth, eyes or genitals - these may be symptoms of something
called ‘Toxic Epidermal Necrolysis’ or ‘Stevens-Johnson Syndrome’
red scaly widespread rash with bumps under the skin (including your skin folds, chest,
abdomen (including stomach), back and arms) and blisters accompanied by fever - these
may be symptoms of something called ‘Acute Generalised Exanthematous Pustulosis’
flu-like symptoms and a rash on the face then an extended rash with a high temperature,
increased levels of liver enzymes seen in blood tests and an increase in a type of
white blood cell (eosinophilia) and enlarged lymph nodes. These may be signs or symptoms
of ‘Drug Reaction with Eosinophilia and Systemic Symptoms’
Other very serious side effects:
kidney problems - shown in tests. Frequency or severity of kidney problems may be
increased if you receive higher doses
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Call your doctor or nurse straight away, or go straight to the Emergency Department
at your nearest hospital if you notice any of these very serious side effects. You may need urgent medical attention or hospitalisation. These side effects are
very rare.
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Tell your doctor or pharmacist if you notice anything else that may be making you
feel unwell.
Other side effects not listed here may occur in some people.
Reporting side effects
By reporting side effects, you can help provide more information on the safety of
this medicine.
Always make sure you speak to your doctor or pharmacist before you decide to stop
taking any of your medicines.
7. Product details
This medicine is only available with a doctor's prescription.
What Targocid contains
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Active ingredient
(main ingredient)
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Teicoplanin
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Other ingredients
(inactive ingredients)
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Sodium chloride
Water for injections
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Potential allergens
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Targocid does not contain gluten, dyes or preservatives.
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Do not take this medicine if you are allergic to any of these ingredients.
What Targocid looks like
Targocid injection is presented in a glass vial as a white powder which your doctor,
pharmacist or nurse will mix with the ampoule of sterile water, included in the pack.
A clear solution is formed when the powder is mixed with the water.
Who distributes Targocid
Distributed in Australia by:
sanofi-aventis australia pty ltd
12-24 Talavera Road
Macquarie Park NSW 2113
Freecall: 1800 818 806
Distributed in New Zealand by:
Pharmacy Retailing (NZ) Ltd t/a Healthcare Logistics
PO Box 62027
Sylvia Park Auckland 1644
Freecall: 0800 283 684
This leaflet was prepared in September 2024.
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