“Viva Saliva” is a thorough guide for experts interested in improving their laboratory methods. It provides an in-depth look at salivary sample preparation and saliva hormone testing, integrating peer-reviewed research with Tecan's results.
The Book is intended to improve laboratory accuracy and efficiency by providing critical insights into adopting advanced saliva-based hormone testing in research and diagnosis settings.
Introduction to saliva diagnostics
The first chapter establishes saliva as the gold standard diagnostic tool, highlighting its simplicity of collection and non-invasive nature.
Saliva is known for its reliability and consistency across many patient populations, including children and the elderly. The chapter discusses the significance of improving pre-analytics for saliva testing, including best practices for saliva collection, sample equipment, storage, and processing.
Steroid hormone analysis chapters
- Cortisol – Chapter 2: This chapter discusses cortisol's significant involvement in the stress response besides various other points of regulating, e.g., sleep-wake cycle and blood pressure. The chapter depicts cortisol's diurnal cycles, the definition of normal ranges, and particular diseases such as Cushing's syndrome and Addison's Disease. Detailed information on Tecan's cortisol saliva tests and their benefits is provided to improve lab procedures.
- Testosterone – Chapter 3: This chapter examines testosterone measurement methods, focusing on typical levels in men and women, as well as diurnal changes and seasonal trends. It examines testosterone's role in andrology, gynaecology, paediatrics’, and sports medicine. The benefits and test properties of Tecan's testosterone saliva tests are discussed, which contribute to laboratory efficiency and accuracy.
- Progesterone – Chapter 4: The book investigates progesterone's physiological effects, including its role in ovulation, pregnancy, and the menstrual cycle. It emphasizes progesterone's function in detecting luteal phase insufficiency and menstrual cycle abnormalities. The chapter contains valuable recommendations and substantial pre-analytical data on Tecan's progesterone saliva tests.
- Estradiol and Estriol – Chapter 5: This section discusses the biology of estradiol and its role in puberty, estrogen insufficiency, and diseases such as premature ovarian failure and amenorrhea. Additionally, the clinical significance of measuring estradiol and estriol is highlighted, as well as Tecan's saliva tests for these hormones, which are essential tools for hormone analysis, are part of this chapter.
- DHEA – Chapter 6: In this chapter DHEA's physiological role, normal ranges, and applications in endocrinology, anti-aging medicine, psychology, and sports medicine is discussed. It also offers information about Tecan’s DHEA immunoassays and their testing properties, which contributes to the accuracy and efficiency of laboratory processes.
- Melatonin – Chapter 7: The last hormone covered in the book is melatonin, focusing on its measurement and the properties of Tecan's melatonin-direct saliva ELISA. Practical recommendations and substantial pre-analytics data are supplied to aid laboratory implementation.
Practical applications and future research
"Viva Saliva" combines Tecan's published and unpublished data, providing a solid foundation for establishing or upgrading saliva-based testing capabilities. It identifies potential topics for future study, promoting more investigation into saliva's diagnostic uses.
This Book is essential for professionals looking to improve their laboratory methods since it provides proven research, practical advice, and insights into specific hormone analyses. It combines scientific experience with practical knowledge, making it an invaluable resource for comprehending the distinct properties of saliva in diagnostics and their influence on general health.
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About IBL International GmbH, Part of Tecan Group
IBL International has nearly 30 years experience in development, production and sales of immunodiagnostic products, and is an expert in these fields. Our product portfolio contains enzyme-, radio- and luminescence immunoassays that covers over 1000 products in a broad range of in-vitro diagnostics for research and routine. These products are designed for manual use, but can be easily adapted for open automated systems. We also have a large selection of “niche products” for special applications to complete our product line.
IBL International also focuses on special test systems outside of the standard routine diagnostic tests. For example, we carry immunoassays for the determination of Neurotransmitters or other biogenic amines, steroid hormones in saliva, HMGB1, Neopterin and assays for Alzheimer’s research. We are continuously refining our immunoassays to assure high quality and reliable products. IBL International has a widespread distribution network in over 90 countries. We support our national and international customers with our professional team of product managers and customer service professionals.
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