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Early embryos are prone to chromosomal copying errors, new research shows

A new discovery by researchers at the RIKEN Center for Biosystems Dynamics (BDR) in Japan upends decades of assumptions regarding DNA replication.

28 Aug 2024

New photoacoustic probes could revolutionize brain activity imaging

To understand the brain better, we need new methods to observe its activity.

28 Aug 2024

Study introduces a novel approach to mapping protein-receptor interactions

One in every three FDA-approved drugs targets a single superfamily of receptors dotting the surfaces of human cells.

28 Aug 2024

CDCA7 identified as key player in hemimethylation sensing

DNA methylation is a process in which a methyl group is attached to the cytosine base of the DNA molecule, and a major way that DNA is epigenetically marked.

28 Aug 2024

Innovative berry-based skin spray targets hospital-acquired bacteria

VTT has developed a skin spray, based on nanocellulose and antimicrobial compounds from wild berries, which can be used to treat wounds and eliminate hospital-acquired bacteria such as MRSA before surgery.

28 Aug 2024

Cell therapy commercialization: Streamline your path to cell therapy commercialization

Moving your cell therapy clinical trial beyond Phase I is an exciting time, marking a significant milestone. There are many therapeutic developers working to address critical patient needs in oncology, auto-immune, regenerative medicine, and other spaces.

From Charles Rivers Laboratories Cell and Gene Therapy 28 Aug 2024

SciY and Allchemy announce strategic distribution agreement

SciY is proud to announce a strategic distribution agreement with Allchemy, a pioneer in Artificial Intelligence (AI) driven drug discovery, co-founded by renowned experts Dr. Sara Szymkuć and Prof. Bartosz Grzybowski.

From SciY 28 Aug 2024

AHN myLab® 96 well plate centrifuge

With the age of single-tube PCR reactions fast being eclipsed by microplate-based PCR setups, scientists need tools that are equal to the task. The AHN myLab® PCR plate spinner is designed to offer dependable performance for all PCR plate applications.

From AHN Biotechnologie GmbH 28 Aug 2024

AHN Biotechnologie GmbH – Premium private label manufacturing biotechnology

From our earliest days in the industry, AHN Biotechnologie GmbH has experienced much success with manufacturing equipment and consumables for laboratories around the world.

From AHN Biotechnologie GmbH 28 Aug 2024

Benefits of less intensive stem cell transplants for sickle cell disease

So-called low-intensity blood stem cell transplants, which use milder conditioning agents than standard stem cell transplants, do not appear to damage the lungs and may help improve lung function in some patients with sickle cell disease (SCD), according to a three-year study of adults who underwent the procedure at the National Institutes of Health (NIH).

28 Aug 2024

Zbtb18 regulates cKit expression for HSC self renewal

The study addresses the complex regulation of HSCs, highlighting p21's multifunctional nature beyond cell cycle control. Through the use of p21-tdTomato mice, researchers differentiate between p21-tdT+ and p21-tdT− HSCs. Results show that p21-tdT+ HSCs display increased self-renewal and reconstitution abilities. Zbtb18, upregulated in p21-tdT+ HSCs, is crucial for their repopulation capability. p21 interacts with ZBTB18 to suppress cKit, influencing HSC self-renewal.

28 Aug 2024

LncRNA ZNF593-AS offers hope for heart disease treatment

The research presented in the article delves into the regulatory role of the long non-coding RNA (lncRNA) ZNF593-AS in cardiac hypertrophy and myocardial remodeling, processes that are pivotal in the progression of heart failure and other cardiovascular diseases. The study uncovers how ZNF593-AS exerts its inhibitory effects by upregulating the expression of Mitofusin 2 (Mfn2), a protein known for its role in the regulation of mitochondrial dynamics and cellular metabolism.

28 Aug 2024

Artificial intelligence differentiates cancer cells and detects early viral infections

Researchers at the Centre for Genomic Regulation (CRG), the University of the Basque Country (UPV/EHU), Donostia International Physics Center (DIPC) and the Fundación Biofisica Bizkaia (FBB, located in Biofisika Institute) have developed an artificial intelligence which can differentiate cancer cells from normal cells, as well as detect the very early stages of viral infection inside cells.

27 Aug 2024

Scientists discover how a gut insulin antagonist controls fat loss in C. elegans by modulating brain signals

Researchers have identified an endogenous insulin antagonist, INS-7, in Caenorhabditis elegans that modulates fat loss by inhibiting a gut-to-brain signaling pathway involving the neuropeptide FLP-7.

27 Aug 2024

Study illuminates CDCA7's role in DNA methylation

DNA methylation, a process by which methyl groups are added to DNA molecules, is essential for the maintenance of DNA and the overall health of an organism.

27 Aug 2024

Study reveals a rare genotype with significant impact on women's health

Scientists at deCODE genetics and collaborators, have identified a sequence variant in the CCDC201 gene that when inherited from both parents homozygous causes menopause on average nine years earlier.

27 Aug 2024

New techniques in RNA engineering promise longer-lasting therapies

New methods to shape RNA molecules into circles could lead to more effective and long-lasting therapies, shows a study by researchers at the University of California San Diego.

27 Aug 2024

Novel bottom-up approach in synthetic immunology opens a new frontier for disease treatment

Synthetic immunology, an innovative field of research which could lead to fundamentally new approaches and methods in the treatment of infectious diseases and cancer, is the topic of an article in the "Perspectives" section of the journal "Nature Nanotechnology". Herein, Heidelberg researchers Prof. Dr. Kerstin Göpfrich, Prof. Dr. Michael Platten, Prof. Dr. Friedrich Frischknecht, and Prof. Dr. Oliver T. Fackler describe a so-called bottom-up approach that uses the toolbox of nanotechnology and synthetic biology to construct systems from molecular building blocks and specifically equip them with immune functions.

27 Aug 2024

Step up your cosmetics manufacturing with OHAUS!

Compliance with complex regulations and Good Manufacturing Practices is vital for cosmetics manufacturers to ensure product safety and maintain consumer trust.

From OHAUS Corporation 27 Aug 2024