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UAB researchers identify cell-surface marker that indicates fate of T cells

Follicular helper T cells, or Tfh cells, have a crucial role in immune defense. Without Tfh cells, B cells cannot form germinal center, or GC, responses during which high-affinity antibodies are generated.

14 Aug 2023

Transparent crystal ribcage for real-time imaging of lung function

Researchers develop the ‘crystal ribcage,’ a transparent ribcage for real-time lung imaging at cellular resolution.

14 Aug 2023

The role of self-extracellular nucleic acids in neuroinflammation

Researchers explore the role of self-extracellular nucleic acids in diseases like stroke, multiple sclerosis, Alzheimer’s disease, and Parkinson’s disease.

14 Aug 2023

New insights into severe obesity genetics: Evidence from adults seeking treatment reveals intriguing oligogenic patterns

Researchers explore the prevalence of rare genetic forms of obesity in a United Kingdom-based clinical obesity cohort.

14 Aug 2023

Exploring DNA methylation biomarkers of multiple sclerosis

Researchers identify cell-specific DNA methylation signatures associated with MS.

14 Aug 2023

Significant association found between the rs1205 T-Dom genotype and risk of COVID-19 death or hospitalization among American Indians

Researchers identify an association between the C-reactive protein gene variant rs1205 and COVID-19 severity.

14 Aug 2023

Unveiling α1-AR secrets: breakthrough structures and targeted drug design

Researchers explored the structural basis of agonist specificity of α1A-adrenergic receptors (α1-ARs).

14 Aug 2023

Researchers design one-step procedure for improving effective of adoptive cell immunotherapy against solid tumors

Researchers developed a one-step method to engineer multifunctional M1 phenotype macrophages.

14 Aug 2023

Unveiling hidden threats: clustering loops in CAR-T cells impact cancer therapy

How complementarity-determining region (CDR) loops in the single-chain variable fragment (scFv) influence chimeric antigen receptor (CAR)-T cell behavior.

14 Aug 2023

Scientists develop synthetic extracellular matrix to support growth of mini endometrium in a dish

Scientists have developed a synthetic extracellular matrix (ECM) that can support the growth of a mini endometrium in a dish for at least two weeks.

11 Aug 2023

Research illustrates the role of Gasdermin D protein in immunity tolerance to food

A research team led by Prof. ZHU Shu from the University of Science and Technology of China (USTC) of the Chinese Academy of Sciences (CAS) illustrated the role of Gasdermin D (GSDMD) protein in immunity tolerance to food in the small intestine.

11 Aug 2023

CRISPR/sgRNA-SAM therapy: a potential breakthrough for Parkinson's disease?

Researchers utilize the CRISPR-Cas9 system to induce the synthesis of dopamine (DA) in the brains of a rat model for Parkinson’s disease.

11 Aug 2023

Brain development linked to the emergence of autism spectrum disorder

Two distinct neurodevelopmental abnormalities that arise just weeks after the start of brain development have been associated with the emergence of autism spectrum disorder, according to a new Yale-led study in which researchers developed brain organoids from the stem cells of boys diagnosed with the disorder.

10 Aug 2023

Scientists develop new technique to "tattoo" living cells with nanomaterials

For now, cyborgs exist only in fiction, but the concept is becoming more plausible as science progresses.

10 Aug 2023

Scientists develop "universal pan-mammalian clock" to accurately estimate age in mammals

Scientists at UCLA David Geffen School of Medicine and UCLA Health led an international research team that published two articles detailing changes in DNA – changes that researchers found are shared by humans and other mammals throughout history and are associated with life span and numerous other traits.

10 Aug 2023

Study provides clues to how harmful T cells cause heart disease

Scientists can finally hunt down a harmful kind of human T cell, thanks to new research led by scientists at La Jolla Institute for Immunology (LJI) and the Medical College of Georgia (MCG) at Augusta University.

10 Aug 2023

New pathway for HIV to enter nucleus of healthy cells identified

A study published on August 10, 2023 in the journal Nature Communications has identified a new pathway that human immune deficiency virus (HIV) uses to enter the nucleus of a healthy cell, where it can then replicate and go on to invade other cells.

10 Aug 2023

Newly identified helicase might hold the key to a novel family of anti-COVID-19 drugs

Researchers used a multidisciplinary approach to investigate a nonstructural protein essential in SARS-CoV-2 replication.

10 Aug 2023

Exploring molecular mechanisms and genetic dysregulation in aging and age-associated diseases

Researchers review existing data on the molecular basis of senescence and neurodegeneration in age-related brain diseases.

10 Aug 2023

MaxCyte signs strategic platform license with Lyell Immunopharma

MaxCyte, Inc., a leading, cell-engineering focused company providing enabling platform technologies to advance the discovery, development and commercialization of next-generation cell-based therapeutics and to support innovative, cell-based research, today announced the signing of a strategic platform license (SPL) with Lyell Immunopharma, Inc., a clinical stage T cell reprogramming company.

From MaxCyte, Inc. 10 Aug 2023

Life Science News

UAB researchers identify cell-surface marker that indicates fate of T cells

Transparent crystal ribcage for real-time imaging of lung function

The role of self-extracellular nucleic acids in neuroinflammation

New insights into severe obesity genetics: Evidence from adults seeking treatment reveals intriguing oligogenic patterns

Exploring DNA methylation biomarkers of multiple sclerosis

Significant association found between the rs1205 T-Dom genotype and risk of COVID-19 death or hospitalization among American Indians

Unveiling α1-AR secrets: breakthrough structures and targeted drug design

Researchers design one-step procedure for improving effective of adoptive cell immunotherapy against solid tumors

Unveiling hidden threats: clustering loops in CAR-T cells impact cancer therapy

Scientists develop synthetic extracellular matrix to support growth of mini endometrium in a dish

Research illustrates the role of Gasdermin D protein in immunity tolerance to food

CRISPR/sgRNA-SAM therapy: a potential breakthrough for Parkinson's disease?

Brain development linked to the emergence of autism spectrum disorder

Scientists develop new technique to "tattoo" living cells with nanomaterials

Scientists develop "universal pan-mammalian clock" to accurately estimate age in mammals

Study provides clues to how harmful T cells cause heart disease

New pathway for HIV to enter nucleus of healthy cells identified

Newly identified helicase might hold the key to a novel family of anti-COVID-19 drugs

Exploring molecular mechanisms and genetic dysregulation in aging and age-associated diseases

MaxCyte signs strategic platform license with Lyell Immunopharma

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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