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First crystal structure of alternative DNA shape from the insulin gene revealed

The first crystal structure of an alternative DNA shape from the insulin gene has been revealed by a UCL-led research team.

9 Sep 2024

New chemical modification reduces off-target effects in siRNA drugs

Small interfering RNA (siRNA) drugs are a class of therapeutic agents that silence specific genes associated with inherited diseases.

9 Sep 2024

Raw white garlic shows promise in boosting heart health and reducing disease risks

Review highlights the potential health benefits of raw white garlic consumption, particularly in improving cardiometabolic biomarkers and reducing chronic disease risks.

8 Sep 2024

Rethinking cognitive deficits and schizophrenia risk through genetic insights

In a comprehensive review of recent genetic and population studies, published in the peer-reviewed medical journal Genomic Psychiatry (Genomic Press, New York), Professors Michael Owen and Michael O'Donovan of Cardiff University's Centre for Neuropsychiatric Genetics and Genomics present evidence that challenges conventional wisdom about cognitive deficits in schizophrenia

6 Sep 2024

Understanding the cooperation of transcription factors in gene expression

Every cell in our body contains the same DNA, yet liver cells are different from brain cells, and skin cells differ from muscle cells.

6 Sep 2024

Artificial lymphoid organ-chips created to predict vaccine responses in humans

Researchers at the Institut Pasteur in France have developed artificial "lymphoid organ-chips" that recreate much of the human immune system's response to booster vaccines

6 Sep 2024

Study reveals key signaling pathways driving lung cancer metastasis

When it comes to cancer metastasis, it takes two to tango. That was one of the key findings of a new study led by researchers at Memorial Sloan Kettering Cancer Center (MSK): The TGF-beta and RAS signaling pathways work together to spur the spread of cancer in lung adenocarcinoma, a leading cause of cancer deaths around the world.

6 Sep 2024

Study reveals key bacteria for developing personalized probiotics for newborns

Newborn babies have one of three pioneer bacteria in their gut shortly after birth, one of which could be used to develop new personalized infant therapeutic probiotics, researchers show.

6 Sep 2024

New RNA therapy offers hope for mental health

Scientists at Cognigenics have made a significant advance in the field of neuroscience and mental health treatment. Their groundbreaking research, published in Genomic Psychiatry, demonstrates that a new RNA-based therapy called COG-201 can enhance memory and reduce anxiety in animal models.

6 Sep 2024

Scientists reveal how DNA methylation drives astrocytes to become stem cells, unlocking new potential for brain repair

Researchers have discovered that DNA methylation is crucial for reprogramming astrocytes into stem cells in the adult mouse brain, especially after ischemic injury, with potential implications for regenerative medicine.

6 Sep 2024

Harnessing bacteriophages as targeted treatments for drug-resistant bacteria

As antibiotic resistance becomes an increasingly serious threat to our health, the scientific and medical communities are searching for new medicines to fight infections.

5 Sep 2024

Study reveals key cell structure for heat perception in humans

A study by the Medical University of Vienna has made important progress in understanding heat perception in humans.

5 Sep 2024

New dye technique allows for transparent skin imaging in live mice

Seeing what's going on inside a body is never easy. While technologies like CT scans, X-rays, MRIs, and microscopy can provide insights, the images are rarely completely clear and can come with side effects like radiation exposure.

5 Sep 2024

Insilico Medicine partners with Inimmune to advance immunotherapeutic discovery

Insilico Medicine("Insilico"), a clinical-stage generative artificial intelligence (AI)-driven biotechnology company, today announced that the company has achieved a groundbreaking collaboration with Inimmune, which will utilize Chemistry42, Insilico's proprietary generative artificial intelligence (AI) technology to accelerate the discovery and development of next-generation immunotherapeutics.

5 Sep 2024

Fish gut bacteria may provide new ingredients for skincare

There are some pretty strange ingredients in cosmetics and skin care products. One example is snail mucin - also known as snail slime - which is used for its moisturizing and antioxidant properties.

5 Sep 2024

Unraveling psychiatric disorders with cutting-edge epigenetic tools

The "Innovators & Ideas: Rising Star" section of Genomic Psychiatry features an illuminating "Genomic Press Interview" with Dr. Pierre-Eric Lutz, a rising star in the field of neuro-epigenetics.

5 Sep 2024

Breakthrough research identifies key microenvironments linked to kidney injury and disease

A study published in Nature Communications provides new insight into how damaged cells interact within disease-promoting microenvironments following acute kidney injury, or AKI.

5 Sep 2024

New technique promises faster DNA analysis in sexual assault cases

A team of researchers has developed a radical new technique for analyzing evidence in sexual assault cases. The new approach could streamline the forensics pipeline and reduce delays in the processing of DNA evidence.

5 Sep 2024

ERS Genomics and medicines discovery catapult sign CRISPR/Cas9 license agreement

Dublin, Ireland, and Cheshire, UK, 04 September 2024: ERS Genomics Limited (‘ERS’), the CRISPR licensing Company, and Medicines Discovery Catapult (‘MDC’), an independent, not-for-profit drug discovery innovation center, have signed a non-exclusive commercial-use CRISPR license agreement.

From ERS Genomics 5 Sep 2024

A call for robust H5N1 influenza preparedness and response

As the global threat of H5N1 influenza looms with outbreaks across species and continents including the U.S., three international vaccine and public health experts say it is time to fully resource and support a robust strategy to address this and future potential pandemic influenza threats, including to consider voluntary vaccination for those now at exposure risk.

5 Sep 2024