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Honokiol inhibits replication of SARS-CoV-2 in several cell types

A compound called honokiol, which is found in the bark of multiple species of magnolia tree, inhibits replication of SARS-CoV-2 virus in several types of cells, according to a team of researchers in the Netherlands.

22 May 2023

AI-based method predicts small molecule substrates of enzymes

Enzymes are the molecule factories in biological cells. However, which basic molecular building blocks they use to assemble target molecules is often unknown and difficult to measure.

22 May 2023

Newly discovered molecule effectively destroys senescent cells

Over time, the body's cells stop working properly and begin to accumulate, which eventually leads to tissues aging.

22 May 2023

Exploring how and why nitrate has contrasting potential risks and benefits

Despite our understanding of nutrition expanding remarkably in recent times, few aspects of our diet continue to confuse and divide the experts like nitrate.

22 May 2023

New vaccine concept could lead to a new generation of vaccines against SARS-CoV-2

Researchers at the University of Basel have developed a new approach for a vaccine against COVID-19.

22 May 2023

The State of Tech Bio: Survey finds majority of biodevelopers write code and use machine learning; protein engineering is a top priority

Cradle, the platform that helps scientists to design and program proteins, today published the findings of its first BioDeveloper survey, exploring the methods and priorities of biodevelopers to build a picture of trends within the synthetic biology sector.

From Cradle Bio B.V. 22 May 2023

Genetic insights unveil promising therapeutic targets for critical COVID-19

Critical COVID-19 illness reveals genetic associations with immunomodulatory therapies, as identified in a comprehensive analysis of 24,202 cases. This study uncovers novel genome-wide significant associations, highlighting potential druggable targets for inflammatory signaling, immunometabolism, and viral replication, offering insights into therapeutic implications.

21 May 2023

Cross-reactivity between Epstein-Barr virus and protein in multiple sclerosis sheds light on disease development

Research uncovers the association between multiple sclerosis (MS) and antibody reactivity to specific amino acids in CRYAB, along with the increased risk when combined with high EBNA1 responses. The study provides evidence of antibody and T cell cross-reactivity between EBNA1 and CRYAB, highlighting the role of EBV adaptive immune responses in MS development.

21 May 2023

Unraveling the origins of humanity: New research challenges single-origin theory

Researchers explore the complex demographic history of Homo sapiens in Africa, revealing a reticulated population structure dating back to Marine Isotope Stage 5. The study challenges previous assumptions about archaic hominin contributions and emphasizes the significance of employing diverse models for robust inferences about ancient human history.

21 May 2023

Combining generative AI and quantum computing to accelerate drug discovery

Insilico Medicine, a clinical stage generative artificial intelligence (AI)-driven drug discovery company, today announced that it combined two rapidly developing technologies, quantum computing and generative AI, to explore lead candidate discovery in drug development and successfully demonstrated the potential advantages of quantum generative adversarial networks in generative chemistry.

19 May 2023

Genomes of modern humans shaped by admixture events

The course of human history has been marked by complex patterns of migration, isolation, and admixture, the latter a term that refers to gene flow between individuals from different populations.

19 May 2023

Human body odor critical for mosquito host-seeking behavior over long distances, study finds

We know a lot about mosquito preferences up close, but how do mosquitoes find us from up to a hundred meters away? Using an ice-rink-sized outdoor testing arena in Zambia, researchers found that human body odor is critical for mosquito host-seeking behavior over long distances.

19 May 2023

New cell-like transport system could pave the way for development of artificial cells

Biophysicists have designed a new cell-like transport system that represents an important milestone on the road to artificial cells.

19 May 2023

Researchers reveal the cooperative effect of multiple oscillatory signals in biological systems

Oscillatory dynamics in fundamental biological processes, such as circadian clocks, segmentation, and transcription factor responses, requires precise quantitative control for proper cell regulation and fate decisions.

19 May 2023

Researchers use machine learning to identify "synthetic extreme" DNA sequences

Artificial intelligence has exploded across our news feeds, with ChatGPT and related AI technologies becoming the focus of broad public scrutiny.

19 May 2023

Novel gene-editing strategy harnesses an unusual protective ability to eliminate HIV-1 infection

Genetic alterations that give rise to a rare, fatal disorder known as MOGS-CDG paradoxically also protect cells against infection by viruses.

19 May 2023

Researchers receive $2.3 million to continue development of a new ‘glyco-immune’ checkpoint inhibitor

Researchers from Rice University and Baylor College of Medicine are hoping a first-of-its-kind "glyco-immune" checkpoint inhibitor could be the key to stopping bone cancer metastasis for breast cancer survivors.

19 May 2023

Mutation in a ribosomal protein leads to impaired cardiac contractility in mice

A team of researchers have discovered that a mutation in a ribosomal protein found specifically in heart and skeletal muscle leads to impaired cardiac contractility in mice.

19 May 2023

COVID's latest twist: New XBB variant gains strength through recombination, outsmarting immunity and amplifying fusogenicity

Research discusses the emergence of a highly diversified SARS-CoV-2 Omicron subvariant called XBB, which is spreading rapidly around the world. XBB emerged through the recombination of two cocirculating BA.2 lineages, BJ.1 and BM.1.1.1, during the summer of 2022.

18 May 2023

Low-cost, recyclable powder uses sunlight to kill thousands of waterborne bacteria

At least 2 billion people worldwide routinely drink water contaminated with disease-causing microbes.

18 May 2023

Life Science News

Honokiol inhibits replication of SARS-CoV-2 in several cell types

AI-based method predicts small molecule substrates of enzymes

Newly discovered molecule effectively destroys senescent cells

Exploring how and why nitrate has contrasting potential risks and benefits

New vaccine concept could lead to a new generation of vaccines against SARS-CoV-2

The State of Tech Bio: Survey finds majority of biodevelopers write code and use machine learning; protein engineering is a top priority

Genetic insights unveil promising therapeutic targets for critical COVID-19

Cross-reactivity between Epstein-Barr virus and protein in multiple sclerosis sheds light on disease development

Unraveling the origins of humanity: New research challenges single-origin theory

Combining generative AI and quantum computing to accelerate drug discovery

Genomes of modern humans shaped by admixture events

Human body odor critical for mosquito host-seeking behavior over long distances, study finds

New cell-like transport system could pave the way for development of artificial cells

Researchers reveal the cooperative effect of multiple oscillatory signals in biological systems

Researchers use machine learning to identify "synthetic extreme" DNA sequences

Novel gene-editing strategy harnesses an unusual protective ability to eliminate HIV-1 infection

Researchers receive $2.3 million to continue development of a new ‘glyco-immune’ checkpoint inhibitor

Mutation in a ribosomal protein leads to impaired cardiac contractility in mice

COVID's latest twist: New XBB variant gains strength through recombination, outsmarting immunity and amplifying fusogenicity

Low-cost, recyclable powder uses sunlight to kill thousands of waterborne bacteria

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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