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New study aims to elucidate the role of p21 in chronic lung inflammation

A new research paper was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 7, entitled, "p21 facilitates chronic lung inflammation via epithelial and endothelial cells."

18 Apr 2023

Tissue-resident memory cells are key to immunity to Salmonella in mice

Salmonella infections cause about a million deaths a year worldwide, and there is an urgent need for better vaccines for both typhoid fever and non-typhoidal Salmonella disease.

18 Apr 2023

Scientists discover a protein domain that could lead to new COVID-19 treatments

Oak Ridge National Laboratory scientists exploring bioenergy plant genetics have made a surprising discovery: a protein domain that could lead to new COVID-19 treatments.

18 Apr 2023

Light-activated SpyLigation can turn on proteins both inside and outside of living cells

Scientists can now use light to activate protein functions both inside and outside of living cells. The new method, called light-activated SpyLigation, can turn on proteins that are normally off to allow researchers to study and control them in more detail.

18 Apr 2023

New AI-based method for virtual staining of histopathological tissue samples

Researchers from the University of Eastern Finland, the University of Turku, and Tampere University have developed an artificial intelligence-based method for virtual staining of histopathological tissue samples as a part of the Nordic ABCAP consortium. Chemical staining has been the cornerstone of studying histopathology for more than a century and is widely applied in, for example, cancer diagnostics.

18 Apr 2023

IOB researchers identify an active multi-layer embryonic brain circuit

Using a new approach for studying live embryonic mouse brains at single-cell resolution, researchers have identified an active multi-layer circuit that forms in the cortex during an unexpectedly early stage of development. Perturbing the circuit genetically led to changes similar to those seen in the brains of people with autism. The findings are reported today in Cell by a team based at the Institute of Molecular and Clinical Ophthalmology Basel.

18 Apr 2023

Study shows how a biological clock molecule contributes to lung scarring

Abnormal sleep patterns, like those of night-shift workers, disrupt the body's natural biological clock and have been linked to lung health issues.

17 Apr 2023

Gene discovery could pave the way for a non-hormonal male contraceptive

Discovery of a gene in multiple mammalian species could pave the way for a highly effective, reversible and non-hormonal male contraceptive for humans and animals.

17 Apr 2023

Metagenomic sequencing offers rapid, accurate diagnosis of antimicrobial resistance in bloodstream infections

Metagenomic sequencing can provide rapid and actionable antimicrobial resistance predictions to treat bloodstream infections much faster than conventional laboratory tests, and has the potential to save lives and better manage the use of antibiotics, according to new research being presented at this year's European Congress of Clinical Microbiology & Infectious Diseases (ECCMID) in Copenhagen, Denmark (15-18 April).

17 Apr 2023

Study reveals molecular mechanisms that give bacteria its 'superpowers' against antibiotics

A species of ordinary gut bacteria that we all carry flourishes when the intestinal flora is knocked out by a course of antibiotics. Since the bacteria is naturally resistant to many antibiotics, it causes problems, particularly in healthcare settings.

17 Apr 2023

Study unearths 12 different cell types involved in the pathogenesis of coronary artery disease

A new study from the University of Eastern Finland identified 12 different cell types involved in the pathogenesis of coronary artery disease, CAD.

17 Apr 2023

Study offers novel insights into reducing adverse effects of antibiotics on the gut microbiome

Antibiotics help to fight bacterial infections, but they can also harm the helpful microbes living in the gut, which can have long-lasting health consequences.

17 Apr 2023

A highly efficient platform for detection of SARS-CoV-2 variants

The recent outbreak of the coronavirus disease 2019 (COVID-19) pandemic and the continuous evolution of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have highlighted the significance of new detection methods for global monitoring and prevention.

17 Apr 2023

Understanding the prevalence and dissemination aminoglycoside resistance genes

Choosing the appropriate antibiotics to treat bacterial infections has grown more challenging because of the emergence of antibiotic-resistant bacteria.

17 Apr 2023

How SARS-CoV-2 Omicron subvariants have evolved to evade host T-cell immunity

Researchers investigate whether SARS-CoV-2 and its variants have evolved to evade CD8+ T cell-mediated immunity.

15 Apr 2023

Study uncovers a novel fold within the SARS-CoV-2 replication co-factor non-structural protein 9

Researchers present the crystal structure of an anti-non-structural protein 9 specific nanobody in complex with the SARS-CoV-2 nsp9.

15 Apr 2023

First-ever largest atlas of post-zygotic genome mutations in healthy human tissue created

Researchers have created the largest atlas of post-zygotic genome mutations in healthy human tissue ever assembled -; a scientific advancement that could unlock new avenues for diagnosing and treating genetic disease.

13 Apr 2023

B cells use mechanical force to pull antigen molecules off other cells

Most cells evolve slowly, accumulating incremental changes that better suit their environments. Immune cells, because they must adapt rapidly to counter new threats, evolve much more quickly.

13 Apr 2023

New clinical RNA sequencing platform helps carve a path for Precision Child Health

A new clinical RNA sequencing platform at The Hospital for Sick Children (SickKids) is helping to facilitate research into rare genetic conditions and carve a path for Precision Child Health, a movement at SickKids to deliver individualized care for every patient.

13 Apr 2023

Study uncovers hallmarks to improving pancreatic cancer therapy

Scientists from the University of California, Irvine, the University of Michigan and the University of Texas MD Anderson Cancer Center have made a significant contribution to the field of pancreatic cancer research.

13 Apr 2023

Life Science News

New study aims to elucidate the role of p21 in chronic lung inflammation

Tissue-resident memory cells are key to immunity to Salmonella in mice

Scientists discover a protein domain that could lead to new COVID-19 treatments

Light-activated SpyLigation can turn on proteins both inside and outside of living cells

New AI-based method for virtual staining of histopathological tissue samples

IOB researchers identify an active multi-layer embryonic brain circuit

Study shows how a biological clock molecule contributes to lung scarring

Gene discovery could pave the way for a non-hormonal male contraceptive

Metagenomic sequencing offers rapid, accurate diagnosis of antimicrobial resistance in bloodstream infections

Study reveals molecular mechanisms that give bacteria its 'superpowers' against antibiotics

Study unearths 12 different cell types involved in the pathogenesis of coronary artery disease

Study offers novel insights into reducing adverse effects of antibiotics on the gut microbiome

A highly efficient platform for detection of SARS-CoV-2 variants

Understanding the prevalence and dissemination aminoglycoside resistance genes

How SARS-CoV-2 Omicron subvariants have evolved to evade host T-cell immunity

Study uncovers a novel fold within the SARS-CoV-2 replication co-factor non-structural protein 9

First-ever largest atlas of post-zygotic genome mutations in healthy human tissue created

B cells use mechanical force to pull antigen molecules off other cells

New clinical RNA sequencing platform helps carve a path for Precision Child Health

Study uncovers hallmarks to improving pancreatic cancer therapy

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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