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Understanding how to better prescribe probiotics based on our individual microbiome profiles

Understanding how to better prescribe probiotics based on our individual microbiome profiles

Bacteria have thousands of genes and functions that we, the human host, do not have. For instance, bacteria can help us digest fiber, provide support to our immune systems, and absorb important nutrients. But reaping the benefits of "good bacteria" is easier said than done.

28 Mar 2023

Two distinct subtypes of insulin-producing beta cells identified

Two distinct subtypes of insulin-producing beta cells identified

A team led by Van Andel Institute and Max Planck Institute of Immunobiology and Epigenetics scientists has identified two distinct subtypes of insulin-producing beta cells, or ß cells, each with crucial characteristics that may be leveraged to better understand and treat Type 1 and Type 2 diabetes.

28 Mar 2023

3D cell culture system tests how inhibiting fibroblast activities can help treat lung cancer

3D cell culture system tests how inhibiting fibroblast activities can help treat lung cancer

Fibroblasts build and maintain the extracellular matrix, or physical scaffolding for cells, in the connective tissues within the body.

28 Mar 2023

NPC1L1-EGFP mice enable researchers to fluorescently visualize, evaluate vesicular endocytosis

NPC1L1-EGFP mice enable researchers to fluorescently visualize, evaluate vesicular endocytosis

Excessive cholesterol absorption from intestinal lumen contributes to the pathogenesis of hypercholesterolemia, which is a well-established risk factor for atherosclerotic cardiovascular disease.

28 Mar 2023

New molecule slows the effects of one of SARS-CoV-2's more dangerous components

New molecule slows the effects of one of SARS-CoV-2's more dangerous components

Researchers have designed a molecule that slows the effects of one of SARS-CoV-2's more dangerous components – an enzyme called a protease that cuts off the immune system's communications and helps the virus replicate.

28 Mar 2023

Researcher calls evolutionary meddling with genes as "genetic welding"

Researcher calls evolutionary meddling with genes as "genetic welding"

With CRISPR-Cas9 technology, humans can now rapidly change the evolutionary course of animals or plants by inserting genes that can easily spread through entire populations.

28 Mar 2023

Newly found strategy used by metastasized tumors may explain why some promising immunotherapies fail

Newly found strategy used by metastasized tumors may explain why some promising immunotherapies fail

Cancer that has spread to areas like the lungs can apply the brakes to a natural pathway that should recruit killer T cells directly to where it has metastasized, scientists report.

28 Mar 2023

VR imaging system illuminates functional brain network dynamics in autism model

VR imaging system illuminates functional brain network dynamics in autism model

An international research collaboration has developed a VR imaging system that can measure a wide range of neural activity in the cortices of mice during active behavior.

28 Mar 2023

Using a selective dye to label macrophages associated with cancer progression

Using a selective dye to label macrophages associated with cancer progression

M1 and M2 are activated macrophages that protect our immune system and maintain homeostasis.

28 Mar 2023

Speeding Up Sample Preparation to Accelerate Analytical Chemistry

Speeding Up Sample Preparation to Accelerate Analytical Chemistry

In this interview, we speak to Colin Jump, CEO of ePrep, about their products that aim to automate analytical sample preparation.

From ePrep 28 Mar 2023

Renishaw introduces new functionality to its inVia™ confocal Raman microscope

Renishaw introduces new functionality to its inVia™ confocal Raman microscope

Renishaw is pleased to introduce fluorescence lifetime imaging microscopy (FLIM) functionality to its inVia™ confocal Raman microscope.

From Renishaw plc - Additive Manufacturing for Healthcare Applications 28 Mar 2023

Study details bacterial agents in 418 ticks extracted from humans in France

Study details bacterial agents in 418 ticks extracted from humans in France

In a recent study published in the journal Emerging Infectious Diseases, researchers analyzed ticks that bit humans between January 2014 and March 2021 in France for the presence of bacterial pathogens.

27 Mar 2023

Using a long-read approach to gain better understanding of DNA mutations in cancer genomes

Using a long-read approach to gain better understanding of DNA mutations in cancer genomes

Looking to learn more from genomics sequencing about DNA mutations and cancer, researchers applied a long-read approach to get a broader genomic view.

27 Mar 2023

Pneumolysin toxin holds promise for developing therapies against Streptococcus pneumoniae

Pneumolysin toxin holds promise for developing therapies against Streptococcus pneumoniae

In a recent study published in the journal PLoS ONE, researchers in Spain performed a systematic review of pneumolysin (PLY) toxin as a molecular target to develop novel therapeutics against Streptococcus pneumoniae.

27 Mar 2023

Dormant cone photoreceptors in the degenerating retina may retain visual function, research suggests

Dormant cone photoreceptors in the degenerating retina may retain visual function, research suggests

New UCLA research in mice suggests that "dormant" cone photoreceptors in the degenerating retina are not dormant at all, but continue to function, producing responses to light and driving retinal activity for vision.

27 Mar 2023

Chronological and biological age may be important determinants of vaccine-preventable outcomes

Chronological and biological age may be important determinants of vaccine-preventable outcomes

A new editorial paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 5, entitled, "Parsing chronological and biological age effects on vaccine responses."

27 Mar 2023

Myeloid cells can harbor HIV in people taking antiretroviral therapy

Myeloid cells can harbor HIV in people taking antiretroviral therapy

A subset of white blood cells, known as myeloid cells, can harbor HIV in people who have been virally suppressed for years on antiretroviral therapy, according to findings from a small study supported by the National Institutes of Health.

27 Mar 2023

Computational approach used to understand the mechanisms of protein folding in tauopathies

Computational approach used to understand the mechanisms of protein folding in tauopathies

A team at UT Southwestern has developed a computational approach to uncover mechanisms of protein misfolding linked to neurodegenerative diseases.

27 Mar 2023

Researchers discover a new role for one of the genes linked to hereditary spastic paraplegia

Researchers discover a new role for one of the genes linked to hereditary spastic paraplegia

Researchers from the University of Seville and the Seville Institute of Biomedicine (IBiS), in collaboration with the University of Cambridge, have identified a new role for one of the genes related to hereditary spastic paraplegia.

27 Mar 2023

New statement suggests next steps to interpret incidentally identified gene variants related to heart disease

New statement suggests next steps to interpret incidentally identified gene variants related to heart disease

Increasing use of genetic testing means people may discover they have a gene variant associated with some types of cardiovascular disease (CVD).

27 Mar 2023

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