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Study reveals new strategy to combat antibiotic resistance

A new strategy to combat antibiotic resistance has emerged from a study led by researchers at Baylor College of Medicine. Published in the journal Molecular Cell, the report reveals for the first time how bacteria evolve mutations that confer antibiotic resistance and that this process can be inhibited with FDA-approved drug edaravone.

2 Apr 2019

New analysis establishes global microbial signatures for colorectal cancer

Cancers have long been known to arise due to environmental exposures such as unhealthy diet or smoking. Lately, the microbes living in and on our body have entered the stage as key players: while stomach cancer can be caused by a single bacterial species, Helicobacter pylori, the role that gut microbes play in the development of colorectal cancer - the third most common cancer worldwide - is less clear.

2 Apr 2019

Study finds gene variant which causes hairlessness in dogs

Hairlessness in dogs can be the result of deliberate breeding or, in certain breeds, a defect. A recent study completed at the University of Helsinki describes a gene variant in the SGK3 gene, which causes hairlessness in Scottish Deerhounds.

2 Apr 2019

Study finds cellular protein as a 'gas pump attendant' of cancer development

The cells which make up our body vary significantly. A liver cell does not look like a muscle cell and each has a unique function. This is because liver cells produce the proteins that characterize them, and muscle cells do the same.

1 Apr 2019

3D Bioprinting and its Applications

In this interview, AZoM speaks to members of SunP Biotech about 3D bioprinting and its applications.

From SunP Biotech 1 Apr 2019

Scientists have more evidence of why clear margins in breast cancer surgery are such good news

When a breast cancer tumor is removed with no signs of cancer left behind, it's great news for patients, and now scientists have more evidence of why.

1 Apr 2019

Researchers discover natural gene therapy for intractable skin disease

Pathogenic gene mutations causing a type of intractable skin disease can be eliminated from some parts of patients' skin as they age, according to Hokkaido University researchers and their collaborators in Japan. This represents a form of natural gene therapy.

1 Apr 2019

Scientists develop new accurate computational method to enhance drug target stability

Scientists from the Moscow Institute of Physics and Technology, the Skolkovo Institute of Science and Technology, and the University of Southern California have developed a new computational method for the design of thermally stable G protein-coupled receptors that are of great help in creating new drugs.

30 Mar 2019

Binding affinities of PFASs to Baikal seal PPARα revealed using in vitro and in silico approaches

A team of researchers at Ehime University revealed the binding affinities of perfluoroalkyl substances (PFASs) to Baikal seal peroxisome proliferator-activated receptor α (PPARα) using in vitro and in silico approaches.

30 Mar 2019

Young scientists develop cheap and simple catalyst system for organic synthesis

The removal of carboxyl groups and the release of alkyl radical fragments from the tight binding of carboxyl groups are one of the most interesting and promising directions in organic synthesis, especially in the field of new drug synthesis.

30 Mar 2019

Research reveals genomic basis of acute erythroid leukemia

Acute erythroid leukemia is a high-risk cancer with a dismal prognosis, uncertain genetic basis and controversy surrounding the diagnosis. That is changing, thanks to research led by St. Jude Children's Research Hospital that appears today in the journal Nature Genetics.

30 Mar 2019

Study provides better understanding of how cilia work and what causes oscillations

Human bodies have some built-in systems to care for themselves. The cells that line our lungs, nose, brain and reproductive system have cilia, which are tiny, hair-like structures designed to sweep out fluids, cells and microbes to stay healthy.

30 Mar 2019

Seemingly identical bacteria may have a different effect

Our gut microbiome - the complement of bacteria we carry around in our intestines - has been linked to everything from obesity and diabetes to heart disease and even neurological disorders and cancer.

30 Mar 2019

Novel EU-funded project in the field of genomics

The European Advanced infraStructure for Innovative Genomics (EASI-Genomics), a project funded under the European Union's research and innovation programme Horizon 2020, will provide researchers free-of-charge access to cutting-edge European genomics facilities.

30 Mar 2019

Designer organelles in living mammalian cells can build synthetic proteins

A research team led by biophysical chemist Professor Edward Lemke has engineered a designer organelle in a living mammalian cell in a new complex biological translation process. The created membraneless organelle can build proteins from natural and synthetic amino acids carrying new functionalities.

30 Mar 2019

Study highlights need to diversify population-level genetic data for better disease prediction

Polygenic scores can predict a person's risk for conditions like coronary artery disease, breast cancer, and type 2 diabetes (T2D) with great accuracy, even in patients who lack common warning signs. This new genome analysis tool holds promise for physicians, who may be able to intervene earlier to help prevent common disease for at-risk individuals.

30 Mar 2019

Bruker acquires cloud-based scientific software provider Arxspan

Bruker Corporation today announced that it has acquired Arxspan LLC, a provider of cloud-based scientific software and workflow solutions, based in Southborough, Massachusetts.

From Bruker BioSpin - NMR, EPR and Imaging 30 Mar 2019

Study finds two new genes in the developmental defects of canine enamel

In addition to humans, hereditary disorders of enamel development occur in dogs, greatly impacting their dental health and wellbeing. A recent study reveals canine enamel disorders similar to those found in humans, linking them with ENAM and ACP4, two genes previously described in humans.

29 Mar 2019

Pediatric Cell Atlas needed for better understanding of children’s health and illnesses

Research efforts to comprehensively map adult human cells are in progress. But in a Perspective publishing March 28 in the journal Developmental Cell, researchers argue that there is a need to map children’s cells with the same level of granularity.

29 Mar 2019

Single lineage of stem cells contributes to lifelong hippocampal neurogenesis in mice

Scientists once thought that mammals entered adulthood with all of the neurons they would ever have, but studies from the 60s found that new neurons are generated in certain parts of the adult brain and pioneering studies from the 90s helped identify their origins and function.

29 Mar 2019