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Discovery of potent compound in native California shrub may lead to treatment for Alzheimer's

The medicinal powers of aspirin, digitalis, and the anti-malarial artemisinin all come from plants. A Salk Institute discovery of a potent neuroprotective and anti-inflammatory chemical in a native California shrub may lead to a treatment for Alzheimer's disease based on a compound found in nature.

21 Feb 2019

Study gives a snapshot of crocodile evolution

The story that's often told about crocodiles is that they're among the most perfectly adapted creatures on the planet - living fossils that have remained virtually unchanged for millions of years.

21 Feb 2019

Protecting small forests will not maintain bird biodiversity over the long run, shows study

Simply protecting small forests will not maintain the diversity of the birds they support over the long run, a Rutgers-led study says. Forests need to be carefully monitored and managed to maintain their ecological integrity.

21 Feb 2019

Study quantifies hepatic and intestinal mRNA expression of Ugt isoforms in rats

In pharmaceutical companies, rats are used commonly in nonclinical studies to investigate the safety, efficacy, and pharmacokinetic profiles of drug candidates before they are entered into clinical studies. Most compounds administered via the oral route are metabolized in the liver and intestine, so the metabolism is a key determinant of pharmacokinetics.

20 Feb 2019

Scientists demonstrate influence of food odors on proteostasis

The smell of food induces a variety of physiological processes in our body. Thus, the production of saliva and digestive enzymes is stimulated before the actual food intake in order to prepare the gastrointestinal tract for the upcoming digestive process.

20 Feb 2019

Material used to filter beer and wine could transfer heavy metals to it

A frosty mug of beer or ruby-red glass of wine just wouldn't be the same if the liquid was murky or gritty. That's why producers of alcoholic beverages usually filter them.

20 Feb 2019

Researchers unlock the secret behind reproduction of fish called ‘Mary’

A female stickleback fish, nick-named 'Mary', has produced offspring from eggs that appear to have been fertilized while they were still inside her, according to scientists at the University of Nottingham.

20 Feb 2019

Combination of common antibiotics can eliminate multi-drug resistant E. coli

A group of scientists in Denmark is trying to get one step ahead in the battle against antibiotic resistance.

20 Feb 2019

Mogrify to accelerate novel IP and cell therapies using $3.7m USD funding

Mogrify today announced a second close on its seed funding, bringing the total raised to $3.7 million USD, and the appointment of Darrin Disley as CEO.

20 Feb 2019

Scientists probe into the mind of worms to unravel how memories form

Try as you might, some events cannot be remembered. Known in psychology as memory blocking, the phenomenon has remained elusive since first described more than half a century ago.

20 Feb 2019

Axcend begins shipping of shoe-box-sized, high-performance liquid chromatograph

Axcend Corporation today announced it has begun shipping the Axcend Focus LC — a shoe-box-sized, high-performance liquid chromatograph the company believes has the potential to revolutionize the use and deployment of HPLC systems around the globe.

From Axcend Corp. 20 Feb 2019

Researchers engineer stem cell with ‘suicide genes’ to induce cell death in all but beta cells

Researchers have been advancing methods to generate insulin-producing beta cells from pluripotent stem cells for the clinical treatment of type 1 diabetes.

20 Feb 2019

University of Dundee partners with Takeda to develop new treatments for tau pathology

The University of Dundee Drug Discovery Unit has announced a partnership with Takeda, Japan's largest pharmaceutical company, to develop possible new therapeutic treatments for tau pathology, an underlying feature in several forms of neurodegeneration, including Alzheimer's disease.

20 Feb 2019

Researchers take closer look at how viruses bind cells and cause infection

Researchers at Cardiff University have used x-ray crystallography and computer simulation to get a closer look at how viruses bind cells and cause infection.

20 Feb 2019

Researchers unlock plant’s secret of producing specialized metabolites

Plants are master chemists, and Michigan State University researchers have unlocked their secret of producing specialized metabolites.

20 Feb 2019

Gene therapy restores hearing in mice with congenital genetic deafness

In collaboration with the universities of Miami, Columbia and San Francisco, scientists from the Institut Pasteur, Inserm, CNRS, Collège de France, Sorbonne University and the University of Clermont Auvergne have managed to restore hearing in an adult mouse model of DFNB9 deafness - a hearing disorder that represents one of the most frequent cases of congenital genetic deafness.

19 Feb 2019

Study shows how 3D organization of genetic material helps perpetuate the species

From fathers to children, the delivery of hereditary information requires the careful packing of DNA in sperm. But just how nature packages this DNA to prepare offspring isn't clear.

19 Feb 2019

Researchers identify suicide toxin in the bacteria responsible for tuberculosis

The bacteria responsible for tuberculosis can be killed by a toxin they produce unless it is neutralized by an antidote protein. The European team of scientists behind this discovery is coordinated by researchers from the Institute of Pharmacology and Structural Biology and the European Molecular Biology Laboratory.

18 Feb 2019

Researchers identify multiple genetic variants associated with body fat distribution

A new breakthrough from the Genetic Investigation of Anthropometric Traits consortium, which includes many public health researchers from the University of North Carolina at Chapel Hill, identifies multiple genetic variants associated with how the body regulates and distributes body-fat tissue.

18 Feb 2019

Using light-based method for production of pharmaceutical molecules

Photoelectrochemical cells are widely studied for the conversion of solar energy into chemical fuels. They use photocathodes and photoanodes to "split" water into hydrogen and oxygen respectively.

18 Feb 2019