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Identifying gene variants that contribute to ovarian reserve may improve female fertility

For a woman to conceive and deliver a healthy baby, thousands of genes have to work correctly and together. These include genes controlling fertility factors such as the ovarian reserve, the capacity of ovaries to produce viable and fertilizable oocytes, or eggs.

20 Jun 2018

Study provides insights into how components of different cells in the brain are altered

Scientists have revealed that protein molecules in the brain are broken down and replaced at different rates, depending on where in the brain they are.

20 Jun 2018

Increasing biodefense risks posed by synthetic biology

A US Department of Defense commissioned study has found that there are several genetic-engineering tools that could be used to devise biological weapons in a short amount of time.

19 Jun 2018

Scientists identify novel genes linked with infantile forms of schizophrenia

Scientists at the Montreal Neurological Institute and Hospital and McGill University have identified novel genes associated with a specific form of schizophrenia.

19 Jun 2018

Study provides new insight on how antibiotics affect the gut microbiome

New insight on how antibiotics affect the gut microbiome - the community of microbes that live inside us - has been published in the journal eLife.

19 Jun 2018

Mayo Clinic researchers find genetic mutations that increase person's risk for pancreatic cancer

Six genes contain mutations that may be passed down in families, substantially increasing a person's risk for pancreatic cancer. That's according to Mayo Clinic research published in the June 19 edition of the JAMA.

19 Jun 2018

Cells form cage-like structures that trap viruses, find scientists

Scientists have shown that cells can form cage-like structures around viruses to trap them and prevent them from spreading to nearby cells.

19 Jun 2018

Gene signature could improve early diagnosis of TB

Researchers have identified a gene signature that could determine whether a person is going to develop TB, months before they show any symptoms.

19 Jun 2018

Microbiotica partners with University of Adelaide to develop defined bacterial product for ulcerative colitis

Microbiotica, a leading player in microbiome-based therapeutics, today announced that it has entered into an agreement with University of Adelaide as part of its program to develop a defined bacterial product for ulcerative colitis (UC). Financial details have not been disclosed.

19 Jun 2018

Chemists invent new method for remote chiral induction

Chemists at Scripps Research have addressed one of the most formidable challenges in synthetic chemistry by inventing a method for "enantioselective remote meta-CH activation," which enables the making of chiral molecules that were previously difficult or impossible to synthesize.

19 Jun 2018

CytoReason builds largest reference of immune-focused inter-cellular communications

New data published in Nature Biotechnology, represents the largest ever analysis of immune cell signaling research, mapping more than 3,000 previously unlisted cellular interactions, and yielding the first ever immune-centric modular classification of diseases.

19 Jun 2018

Scientists obtain key information about proteins from single human cells

Scientists have obtained a slew of key information about proteins, the molecular workhorses of all cells, from single human cells for the first time.

19 Jun 2018

Scientists could build better drugs by learning from bacteria-derived molecules

Bacteria found in soil may harbor a potential game-changer for drug design. A new study by Scripps Research, published today in Nature Communications, suggests scientists could build better drugs by learning from bacteria-derived molecules called thiocarboxylic acids.

19 Jun 2018

Study: Effects of in vitro fertilization depend on genetic variation inherited from parents

In vitro fertilization affects the regulatory region of genes essential for placental and embryonic growth, as well as the birth weight.

19 Jun 2018

Personal automated cell lab assistant from Leica saves time with quality results

PAULA, the world’s first Personal AUtomated Lab Assistant from Leica Microsystems, is ready to help out cell-lab users. As a new member of the team, PAULA would take over a large number of time-consuming, routine manual tasks that are done in every cell lab.

From Leica Microsystems GmbH 19 Jun 2018

Researchers use optogenetics to shape tissues

Constructing biological tissues, such as skin, muscle, or bone, in customized shapes is now one step closer.

19 Jun 2018

Researchers discover new defense mechanism against oxygen radicals

Oxygen radicals occur as a by-product when living beings burn carbohydrates or fat. They are suspected of accelerating the ageing process in humans and animals, and to be partly responsible for severe illnesses such as Alzheimer's or certain types of cancer.

18 Jun 2018

Scientists discover genetic causes underlying group of related infant cancers

The genetic causes of a group of related infant cancers have been discovered by scientists at the Wellcome Sanger Institute, the University of Wuerzburg and their collaborators.

18 Jun 2018

Gene editing technology predicts heart disease risk

Scientists could now use gene editing and stem cell technologies to predict whether carrying a specific gene variant increases the risk of heart disease.

18 Jun 2018

Study unravels 'blood stem cell niche' puzzle

In humans and other mammals, the stem cells that give rise to all blood cells are located in the bone. But in fish, blood stem cells are found in the kidney. Since the late 1970s, when biologists first realized that blood develops in a specific location in the body — the ‘blood stem cell niche’ — they have wondered why different creatures have evolved to carry out this function in different locations.

18 Jun 2018