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Novel method can edit genes with substantially fewer errors

Gene therapy is an emerging strategy to treat diseases caused by genetic abnormalities. One form of gene therapy involves the direct repair of a defective gene, using genome-editing technology such as CRISPR-Cas9. Despite its therapeutic potential, genome editing can also introduce unwanted and potentially harmful genetic errors that limit its clinical feasibility.

5 Feb 2018

Researchers discover specific taste neurons necessary for protein craving in fruit flies

A team of neuroscientists from the Champalimaud Centre for the Unknown, in Lisbon, Portugal, has discovered that were it not for specific taste neurons located in the fruit fly's proboscis (the equivalent of our tongue), the fly would not develop a craving for protein even when in excruciating need of it.

5 Feb 2018

Novel grape-derived compounds could be developed as therapeutic agents for treatment of depression

In a study to be published online February 2 in Nature Communications, scientists from the Icahn School of Medicine at Mount Sinai describe an extensive analysis of novel grape-derived compounds, dihydrocaffeic acid (DHCA) and malvidin-3'-O-glucoside (Mal-gluc),which might be developed as therapeutic agents for the treatment of depression.

2 Feb 2018

Researchers shine light on ‘molecular butcher’ using neutron beams

Tucked away inside cell membranes, a molecular butcher does the bidding of healthy cells but also of disease agents. It has been operating out of clear view, but researchers just shined a mighty spotlight on it.

2 Feb 2018

Scientists synthesize new multifunctional compound that has anti-tumor properties

A research team of the UNN Faculty of Chemistry led by Professor Alexei Fedorov has developed and synthesized a new multifunctional compound that possesses anti-tumor properties that are due to several independent effects.

2 Feb 2018

Researchers discover gene network that regulates the motor neuron development in growing embryo

UCLA researchers have discovered the inner workings of a gene network that regulates the development of spinal motor neurons in the growing chicken and mouse embryo.

2 Feb 2018

Higher susceptibility of some babies to Zika virus has a genetic origin, study shows

Microcephaly, brain calcification, skeletal alterations, auditory and visual deficits - these are examples of the damage that can be caused by Zika virus in babies born to mothers infected during pregnancy.

2 Feb 2018

Study reveals the mechanism of common DNA mutations

Researchers at The Ohio University have uncovered the mechanism by which thymine and guanine, the most commonly mutated bases in DNA, become damaged.

2 Feb 2018

Scientists develop immune-stimulating injections against cancer

A team of researchers have developed two immune-stimulating injections, that removed all traces of cancer when injected directly into solid mouse tumors.

2 Feb 2018

New ChIPseq kit is optimized for fresh and frozen tissue samples

The new, high-performance Chromatrap ChIP-Seq kit (v.1.5) is optimized to work from fresh and frozen extracted tissue, as well as cell lines.

From Chromatrap® - Porvair Sciences Ltd 2 Feb 2018

Study unravels developmental splicing program that promotes neuronal maturation

Neurons, or nerve cells, in the brain communicate with each other by transmitting electric signals, or firing action potentials, through long processes named axons (which send out signals) and dendrites (which receive signals).

1 Feb 2018

Findings provide better understanding of cell membrane components

Research conducted by Toyohashi University of Technology in collaboration with Tohoku University elucidated the fusion process of proteoliposomes with an artificial lipid bilayer and the mechanism behind this process.

1 Feb 2018

Free magnesium ions regulate chromosome shape, new tool shows

Japanese researchers report a new ion detector, MARIO. Using it, they show that changes in the intracellular concentration of free magnesium ions (Mg2+) is critical for the chromosome folding that must occur for cells to divide.

1 Feb 2018

New technique enables 3D printing of living cells

Using a new technique they call 'in-air microfluidics', University of Twente scientists succeed in printing 3D structures with living cells.

1 Feb 2018

Microbubbles increase radiotherapy success against breast cancer

A new study found that injecting microbubbles filled with oxygen into breast cancer tumors makes them three times more sensitive to radiotherapy.

1 Feb 2018

Scientists discover the genetic cause of immune disorders

Scientists from the Cincinnati Children’s have successfully identified a gene mutation that affects T cell function and promotes immune disorders.

1 Feb 2018

Researchers develop gene therapy for idiopathic pulmonary fibrosis

Researchers have successfully identified the genetic cause of idiopathic pulmonary fibrosis and have shown success in trials of a new gene therapy.

1 Feb 2018

Metrohm presents accurate method for determination of metal-organic compounds by thermometric titration

Metrohm is pleased to present a fast and highly accurate method for the determination of metal-organic compounds by thermometric titration.

From Metrohm USA Inc. 1 Feb 2018

Super-resolution microscopy provides insights into cells' amazing flexibility

One of today's sharpest imaging tools, super-resolution microscopy, produces sparkling images of what until now has been the blurry interior of cells, detailing not only the cell's internal organs and skeleton, but also providing insights into cells' amazing flexibility.

31 Jan 2018

Researchers uncover small molecule that plays key role in protecting against cancer

In a new study, researchers have shown that a small molecule involved in the regulation of gene expression plays an important role in protecting against cancer.

31 Jan 2018

Life Science News

Novel method can edit genes with substantially fewer errors

Researchers discover specific taste neurons necessary for protein craving in fruit flies

Novel grape-derived compounds could be developed as therapeutic agents for treatment of depression

Researchers shine light on ‘molecular butcher’ using neutron beams

Scientists synthesize new multifunctional compound that has anti-tumor properties

Researchers discover gene network that regulates the motor neuron development in growing embryo

Higher susceptibility of some babies to Zika virus has a genetic origin, study shows

Study reveals the mechanism of common DNA mutations

Scientists develop immune-stimulating injections against cancer

New ChIPseq kit is optimized for fresh and frozen tissue samples

Study unravels developmental splicing program that promotes neuronal maturation

Findings provide better understanding of cell membrane components

Free magnesium ions regulate chromosome shape, new tool shows

New technique enables 3D printing of living cells

Microbubbles increase radiotherapy success against breast cancer

Scientists discover the genetic cause of immune disorders

Researchers develop gene therapy for idiopathic pulmonary fibrosis

Metrohm presents accurate method for determination of metal-organic compounds by thermometric titration

Super-resolution microscopy provides insights into cells' amazing flexibility

Researchers uncover small molecule that plays key role in protecting against cancer

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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