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Small molecules in saliva show potential for early diagnosis of Alzheimer's disease

Your spit may hold a clue to future brain health. Investigators at the Beaumont Research Institute, part of Beaumont Health in Michigan, are hopeful that their study involving small molecules in saliva will help identify those at risk of developing Alzheimer's disease - a neurologic condition predicted to reach epidemic proportions worldwide by 2050.

17 May 2017

Experimental gene therapy proven safe for preserving vision of people with AMD

In a small and preliminary clinical trial, Johns Hopkins researchers and their collaborators have shown that an experimental gene therapy that uses viruses to introduce a therapeutic gene into the eye is safe and that it may be effective in preserving the vision of people with wet age-related macular degeneration.

17 May 2017

Researchers discover likely cause for visual impairment in Finnish variant of NCL

Researchers from the University of Eastern Finland have discovered a likely cause for visual impairment and eventual loss of vision in the Finnish variant of Neuronal Ceroid Lipofuscinosis.

17 May 2017

Researchers find macrophages to be crucial for tissue regeneration in mammals

A team of University of Kentucky researchers has discovered that macrophages, a type of immune cell that clears debris at injury sites during normal wound healing and helps produce scar tissue, are required for complex tissue regeneration in mammals.

16 May 2017

Spanish scientists develop promising gene therapy method to treat Wilson's disease

Scientists at the Center for Applied Medical Research at the University of Navarra have designed a promising gene therapy method to treat Wilson's disease, a rare pathology caused by the lack of or malfunction of a gene.

16 May 2017

Researchers identify many dangerous strains of TB pathogens

Researchers from the Vavilov Institute of General Genetics of the Russian Academy of Sciences (VIGG) and the Moscow Institute of Physics and Technology have established a catalog of mutations in 319 virulence genes of mycobacteria that cause tuberculosis.

16 May 2017

Scientists unravel mystery of T cell signaling process vital to immune response

The immune system cells known as T cells play a central role in the body's ability to fight infections and cancer. For decades, however, details of the molecular signaling process that leads to T cell activation have remained a mystery.

16 May 2017

Breast cancer cells undergo stiffening state prior to becoming malignant, study shows

A study published now on Nature Communications shows that breast cancer cells undergo a stiffening state prior to acquiring malignant features and becoming invasive.

16 May 2017

Deep-well plate removes risk of false peaks in uHPLC and MS applications

The new Glass Vial Deep-well plate from Porvair Sciences is designed to ensure that absolutely no extractables or leachates are present in a withdrawn sample, thereby removing the risk of false peaks in sensitive uHPLC and MS applications

From Porvair Sciences Limited 16 May 2017

Prototype drug prevents lung cancer tumors in mice by using novel mechanism

Lung cancer tumors were prevented in mice by a novel small molecule that directly activates a tumor suppressor protein.

16 May 2017

Study unravels new clues to cause and treatment of spinal muscular atrophy

Spinal muscular atrophy, a neurodegenerative disease that causes progressive muscle wasting and paralysis, may be partly due to abnormalities in the synapses that connect sensory neurons and motor neurons, according to researchers at Columbia University Medical Center.

16 May 2017

JAX researcher awarded federal grant for genomic studies of healthy aging and Alzheimer's disease

A grant totaling $2,668,127 over five years will fund studies of the complex processes involved in both healthy aging and Alzheimer's disease, in the laboratory of Jackson Laboratory (JAX) Assistant Professor Catherine Kaczorowski, Ph.D.

16 May 2017

New gene variant linked to Lou Gehrig's disease

For the first time, a variant in UBQLN4 gene has been associated with Lou Gehrig's disease or amyotrophic lateral sclerosis (ALS) - a progressive disease resulting in the loss of nerve cells that control muscle movement, which eventually leads to paralysis and death.

15 May 2017

New research explores small fly’s amazing sense of directional hearing

Ormia ochracea's sense of directional hearing is second to none in the animal kingdom. But, according to new University of Toronto Scarborough research, what makes its hearing so incredible may also complicate efforts in using it as a model for new technology, including hearing aids.

15 May 2017

New type of eye drop could potentially revolutionize treatment of AMD

Scientists at the University of Birmingham have developed a type of eye drop which could potentially revolutionize the treatment of one of the leading causes of blindness in the UK.

15 May 2017

Study sheds new light on inherent ability of normal cells to prevent cancer at the initial stage

A new study shows cells in the initial stage of cancer change their metabolism before getting eliminated by the surrounding normal cells, providing a novel target for developing cancer prevention drugs.

15 May 2017

Research networks focus on investigating spread of antimicrobial resistance in humans, animals

"Antimicrobial-resistant bacteria pose a complex challenge. This is why Germany, with its German Antimicrobial Resistance Strategy DART2020, is making sustained efforts to protect the health of humans and animals", says BfR President Professor Dr. Dr. Andreas Hensel.

12 May 2017

New spherical nucleic acid drug crosses blood-brain barrier to target brain tumors in animals

The first drug using spherical nucleic acids to be systemically given to humans has been developed by Northwestern University scientists and approved by the Food and Drug Administration as an investigational new drug for an early-stage clinical trial in the deadly brain cancer glioblastoma multiforme.

12 May 2017

Analyzing single-cell RNA data in pre-malignant tumors

RNA sequencing is basically the isolation of RNA from cells and the use of reverse transcriptase to turn the RNA into DNA. You can then use your standard DNA sequencing technologies to quantify the cDNA that you obtained from the reverse transcription reaction.

12 May 2017

Researchers uncover structural details that make eye-targeting virus a better tool for future therapies

In their quest to replicate themselves, viruses have gotten awfully good at tricking human cells into pumping out viral proteins. That's why scientists have been working to use viruses as forces for good: to deliver useful genes to human cells and help patients who lack important proteins or enzymes.

12 May 2017

Life Science News

Small molecules in saliva show potential for early diagnosis of Alzheimer's disease

Experimental gene therapy proven safe for preserving vision of people with AMD

Researchers discover likely cause for visual impairment in Finnish variant of NCL

Researchers find macrophages to be crucial for tissue regeneration in mammals

Spanish scientists develop promising gene therapy method to treat Wilson's disease

Researchers identify many dangerous strains of TB pathogens

Scientists unravel mystery of T cell signaling process vital to immune response

Breast cancer cells undergo stiffening state prior to becoming malignant, study shows

Deep-well plate removes risk of false peaks in uHPLC and MS applications

Prototype drug prevents lung cancer tumors in mice by using novel mechanism

Study unravels new clues to cause and treatment of spinal muscular atrophy

JAX researcher awarded federal grant for genomic studies of healthy aging and Alzheimer's disease

New gene variant linked to Lou Gehrig's disease

New research explores small fly’s amazing sense of directional hearing

New type of eye drop could potentially revolutionize treatment of AMD

Study sheds new light on inherent ability of normal cells to prevent cancer at the initial stage

Research networks focus on investigating spread of antimicrobial resistance in humans, animals

New spherical nucleic acid drug crosses blood-brain barrier to target brain tumors in animals

Analyzing single-cell RNA data in pre-malignant tumors

Researchers uncover structural details that make eye-targeting virus a better tool for future therapies

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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