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Scientists overcome major challenge in gene therapy and drug delivery

Imagine trying to poke a hole in the yolk of a raw egg without breaking the egg white. It sounds impossible, but researchers at the University of California San Diego have developed a technology that performs a similarly delicate task in living cells. They created an array of nanopillars that can breach the nucleus of a cell-;the compartment that houses our DNA-;without damaging the cell's outer membrane.

3 Oct 2024

Mount Sinai BioDesign expands collaboration with MedTech community to enhance medical innovation

Mount Sinai Health System today announced that Mount Sinai BioDesign, the medical technology incubator of the Health System, has expanded its reach to become a key, effective partner for the broader MedTech community.

3 Oct 2024

Mediterranean diet significantly lowers heart failure risk, especially in women

Increased adherence to the Mediterranean diet significantly lowers the risk of heart failure, especially in women, according to a recent European meta-analysis. The diet's anti-inflammatory and antioxidant properties are key to its protective effects.

3 Oct 2024

Circadian rhythm influences dementia diagnosis and disease progression

The time of day when blood is taken can affect the results of tests for diagnosing dementia, according to new research led by the University of Surrey.

3 Oct 2024

Study reveals sharp increase in vaping among never-regular smokers in England

The number of adults vaping in England who have never regularly smoked has increased sharply since 2021, when disposable e-cigarettes first became popular, according to a new study by UCL researchers.

3 Oct 2024

Study highlights the role of genetic factors in COVID-19 thrombosis and inflammation

Despite global vaccination efforts, COVID-19 continues to pose significant risks, leading to severe complications and fatalities. These risks are driven by disrupted coagulation, impaired fibrinolysis, which is the process of breaking blood clots, and heightened inflammatory responses.

3 Oct 2024

New insights into the link between respiratory infections and chronic lung diseases

A 3D reconstruction of a mouse lung four days after infection with fluorescent Sendai virus reveals widespread virus presence (red) and active replication (green).

3 Oct 2024

Accelerating tobacco decline could boost global life expectancy

Accelerating the decline in tobacco smoking globally, by decreasing smoking prevalence from current levels to 5% everywhere, could increase life expectancy and prevent millions of premature deaths by 2050, according to a study from the Global Burden of Disease, Injuries and Risk Factors (GBD) Tobacco Forecasting Collaborators published in The Lancet Public Health journal.

3 Oct 2024

Ketogenic diet lowers mortality by 24% while maintaining heart health

Study confirms that adherence to a ketogenic diet reduces all-cause mortality risk by 24% without increasing cardiovascular mortality in a large US cohort. Findings support KD as a beneficial intervention for long-term health.

3 Oct 2024

UK and Singapore partner on health data

Health Data Research UK (HDR UK) and the National Research Foundation Singapore (NRF) are pleased to have signed a Memorandum of Understanding (MoU) today, that formalizes a collaborative partnership in healthcare and data science.

3 Oct 2024

Creating a tobacco-free generation could prevent 1.2 million lung cancer deaths

Creating a generation of people who never smoke could prevent 1.2 million deaths from lung cancer globally, according to a study led by researchers from the University of Santiago de Compostela, the International Agency for Research on Cancer (IARC), and global collaborators published in The Lancet Public Health journal.

3 Oct 2024

Researchers develop technology to change protein identity in vivo

Researchers at the RIKEN Cluster for Pioneering Research (CPR) have developed technology that can alter, within the body, the recognized identity of proteins. The innovation, published in Nature Communications on October 2, allowed researchers to target mouse tumors with a protein and then transport that protein out of the body.

3 Oct 2024

UCLA develops CORE score to assess surgical mortality risk

A UCLA research team has created the Comorbid Operative Risk Evaluation (CORE) score to better account for the role chronic illness plays in patient's risk of mortality after operation, allowing surgeons to adjust to patients' pre-existing conditions and more easily determine mortality risk.

3 Oct 2024

Primary care settings failing to address women's hot flashes

Timely identification and treatment of bothersome hot flashes have the potential to improve the lives of many women and save employers countless days of related absenteeism and lost work productivity. Yet, a new study finds that such symptoms are often not documented in electronic health records (EHRs) or not adequately addressed during primary care visits.

3 Oct 2024