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12-week coffee compound study shows promising results for weight and fat reduction in at-risk individuals

Cafestol may aid in reducing body weight and visceral fat, but its impact on insulin sensitivity and glucose tolerance remains limited, according to the study.

27 Sep 2024

Digital games show promise for improving ADHD and depression in youth, but anxiety remains a challenge

A meta-analysis reveals gamified digital mental health interventions effectively reduce depression and ADHD in youth, highlighting engagement in treatment.

27 Sep 2024

Liver receptor mutations linked to liver dysfunction, cholesterol accumulation, and hepatitis

Damaging LXRα variants are linked to liver cholesterol buildup and hepatitis, emphasizing the receptor's importance in cholesterol sensing and liver function.

27 Sep 2024

TxGNN improves drug repurposing by predicting treatments for rare diseases with no approved therapies

A new model, TxGNN, revolutionizes zero-shot drug repurposing by predicting treatments for diseases with no known therapies, offering improved accuracy and trust via interpretable AI explanations.

27 Sep 2024

Researchers create high-performing, eco-friendly sunscreen

In a significant breakthrough for the cosmetics industry, researchers have developed a new type of sunscreen using lignin, a naturally abundant polymer, and titanium dioxide (TiO2). The study, led by Yarong Li and Zhiguang Tang, was published in the Journal of Bioresources and Bioproducts and details the innovative use of a dual-modified lignin sub-microsphere to enhance the SPF and improve the color of sunscreens.

27 Sep 2024

Computational study identifies spinal circuit that modulates stretch reflexes

How did the bodies of animals, including ours, become such fine-tuned movement machines? How vertebrates coordinate the eternal tug-o-war between involuntary reflexes and seamless voluntary movements is a mystery that Francisco Valero-Cuevas' Lab in USC Alfred E. Mann Department of Biomedical Engineering, set out to understand.

26 Sep 2024

Epigenetic switch controls renin production in unexpected cell type

University of Virginia School of Medicine researchers have discovered how certain cells have the amazing ability to transform their function to help our bodies control our blood pressure.

26 Sep 2024

Revolutionary blueprint aims to enhance nurse's impact on patient outcomes

A groundbreaking article published in the latest issue of Nursing Outlook proposes a significant shift in how nursing care is measured within acute and critical care settings.

26 Sep 2024

Scientists unravel the process of pore formation in cells

The formation of pores by a particular protein, gasdermin D, plays a key role in inflammatory reactions. During its activation, an inhibitory part is split off. More than 30 of the remaining protein fragments then combine to form large pores in the cell membrane, which allow the release of inflammatory messengers.

26 Sep 2024

Hormone hepcidin identified as potential trigger for psoriasis

Scientists may have uncovered the root cause of psoriasis, a chronic and sometimes debilitating skin disease that affects 2-3% of the global population. The condition is characterized by red, scaly patches that impact the quality of a patient's life and can sometimes be life-threatening.

26 Sep 2024

Study links early opportunities to long-term success for children

The number of educational opportunities that children accrue at home, in early education and care, at school, in afterschool programs, and in their communities as they grow up are strongly linked to their educational attainment and earnings in early adulthood, according to new research.

26 Sep 2024

New insights into serine hydroxymethyltransferase aid cancer drug design

In just two neutron experiments, scientists discovered remarkable details about the function of an enzyme that can aid drug design for aggressive cancers.

26 Sep 2024

Study uncovers hidden proteins fueling heart disease and stroke

Researchers identified key proteins linked to cardiovascular disease, highlighting new targets for drug development using genetic and observational analyses in UK and China biobanks.

26 Sep 2024

Iron deficiency common among pregnant women despite supplements

When a woman becomes pregnant, her iron requirements increase almost tenfold to support fetal development as well as her own increased iron needs.

26 Sep 2024

New drug MED6-189 shows promise against drug-resistant malaria

In 2022, nearly 619,000 global deaths due to malaria were caused by Plasmodium falciparum, the most virulent, prevalent, and deadly human malaria parasite.

26 Sep 2024

Climate change to drive increased hospitalizations from diarrheal diseases in Dhaka

By 2100, hospitalizations from diarrheal diseases are predicted to increase in the city of Dhaka in Bangladesh as a result of climate change, even if global warming stays under 2 degrees Celsius.

26 Sep 2024

Cleveland Clinic identifies bacterium that weakens gut immune defense

Cleveland Clinic researchers have discovered a new bacterium that weakens the immune system in the gut, potentially contributing to certain inflammatory and infectious gut diseases.

26 Sep 2024

Targeting brain lesions with TMS shows promise in treating PTSD in veterans

Researchers have identified specific brain lesions associated with reduced PTSD symptoms in veterans, providing a potential noninvasive neuromodulation target. TMS applied to this PTSD circuit could offer new hope for effective treatment.

26 Sep 2024

Study: MMR vaccine remains the most effective measure to prevent measles infection

Most measles cases in England are among unvaccinated individuals. But, between 2011 and 2019, the proportion of measles cases in adults who received two doses of the MMR vaccine in England increased from 1.9% (20/1064) to 7.2% (57/790), however the cause of this increase remains unclear.

26 Sep 2024

Review highlights evolving role of endovascular therapy in treating ischemic stroke

Stroke related to large vessel occlusion (LVO) is a leading cause of disability and death worldwide. Endovascular therapy (minimally invasive procedures like catheterization done inside the blood vessels) has transformed the management of these patients.

26 Sep 2024