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European study indicates cardiovascular deaths can be avoided through better preventative care

Cardiovascular disease (CVD) is the leading cause of death in Europe, killing an estimated 4.3 million people each year. Results from a large pan-European study announced today indicate that many of these deaths could be avoided if at-risk patients received better preventative care.

9 Nov 2010

Smoking increases risk of breast cancer progression in multiethnic women with breast cancer

Being a current smoker or having a history of smoking significantly increased the risk of breast cancer progression and overall death among a group of multiethnic women with breast cancer, according to the results of a large prospective cohort study.

9 Nov 2010

New approach to treat castration resistant prostate cancer

A monoclonal antibody targeting a well known cell surface protein inhibited prostate cancer growth and metastasis in an aggressive form of the disease that did not respond to hormone therapy, according to a study by researchers with the UCLA Department of Urology and UCLA's Jonsson Comprehensive Cancer Center.

9 Nov 2010

Genetic region linked to survival in patients with advanced bowel cancer

Scientists have discovered a genetic region linked to survival in patients with advanced bowel cancer, according to a study being presented at the National Cancer Research Institute (NCRI) Cancer Conference today (Tuesday).

9 Nov 2010

New TB-drugome may help identify protein targets for tuberculosis

Researchers at the University of California, San Diego School of Medicine and the University of Leeds have linked hundreds of federally approved drugs to more than 1,000 proteins in Mycobacterium tuberculosis, the causative agent of tuberculosis (TB), opening new avenues to repurpose these drugs to treat TB.

9 Nov 2010

Sugar-sweetened drinks can increase gout risk in women

Women who consume fructose-rich beverages, such as sugar-sweetened soft drinks and orange juice, are at an increased risk for gout, according to research presented at the Nov 2010, American College of Rheumatology Annual Scientific Meeting in Atlanta.

9 Nov 2010

Chemotherapy for breast cancer does more harm than good

A fundamental principle of medicine is: "first, do no harm." However, for doctors who treat breast cancer, this is easier said than done. Every year, almost 22,000 Canadian women are diagnosed with breast cancer - their treatment usually involves surgery to remove a tumour and then chemotherapy to reduce the risk of cancer returning.

9 Nov 2010

EVP-6124 receptor acts as co-agonist with ACh to enhance cognition

EnVivo Pharmaceuticals today announced it has discovered that EVP-6124, its alpha-7 nicotinic acetylcholine receptor agonist, possesses a novel mechanism not previously seen in the scientific community: it acts as a co-agonist with Acetylcholine (ACh) to enhance cognition.

9 Nov 2010

Valley Anesthesiology Consultants' mobile services division receives AAAHC accreditation

VAC Mobile Services, a division of Valley Anesthesiology Consultants, has achieved accreditation by the Accreditation Association for Ambulatory Health Care (AAAHC). Valley is one of only 10 office-based anesthesia groups nationwide to receive AAAHC accreditation, and the only office-based anesthesia organization in Arizona currently accredited by AAAHC.

9 Nov 2010

Colcrys safe for treating gout flares

Patients who experience gout flares can be treated safely with Colcrys (colchicine, USP), even in the presence of co-morbid conditions that often present physicians with treatment challenges, according to a new analysis presented here at the 74th Annual Scientific Meeting of the American College of Rheumatology (ACR).

9 Nov 2010

Study discovers role of Vav1 oncogene in several cancers

Researchers at the Hebrew University of Jerusalem have discovered that Vav1 - an oncogene (cancer-causing gene) found in recent years to be one of the factors in tumorous tissue growth -- plays a wider role in several types of cancer than had previously been thought. The discovery has implications for further concentration on targeting this gene in cancer research.

9 Nov 2010

Combination of optical and x-ray imaging may improve diagnostic accuracy of breast screening

By combining optical and x-ray imaging, radiologists may be better able to distinguish cancer from benign lesions in the breast, according to a new study published in the online edition and January issue of Radiology.

9 Nov 2010

Scientists develop nanobioconjugate drug to target brain tumor

Nine years ago, scientists at Cedars-Sinai's Maxine Dunitz Neurosurgical Institute detected a subtle shift occurring in the molecular makeup of the most aggressive type of brain tumors, glioblastoma multiforme. With further study, they found that a specific protein called laminin-411 plays a major role in a tumor's ability to build new blood vessels to support its growth and spread. But technology did not exist then to block this protein.

9 Nov 2010

Genta commences tesetaxel Phase 2b clinical trial as 1st-line chemotherapy for metastatic breast cancer

Genta Incorporated today announced that the Company has initiated a new Phase 2b clinical trial of tesetaxel as 1st-line chemotherapy for women with metastatic breast cancer. Tesetaxel is the leading oral taxane currently in clinical development. The new trial will be conducted at Memorial Sloan-Kettering Cancer Center, New York, NY and at the Accelerated Community Oncology Research Network (ACORN) based in Memphis, TN.

9 Nov 2010

SIMPONI injection improves inflammation, structural damage in RA patients

Magnetic resonance imaging (MRI) analyses from two Phase 3 clinical trials showed that once every four week subcutaneous injections of SIMPONI (golimumab) 50 mg plus methotrexate resulted in statistically significant improvements in markers of inflammation and structural damage in patients with active rheumatoid arthritis (RA) compared with placebo plus methotrexate.

9 Nov 2010

Study confirms defect in sweat gland function as disease biomarker for XLHED

Edimer Pharmaceuticals, a biotechnology company focused on developing an innovative therapy for the rare genetic disorder, X-linked Hypohidrotic Ectodermal Dysplasia (XLHED), today announced key findings of a study exploring novel approaches to the assessment of sweat function in males with XLHED. Affected individuals lack a normal sweat response, placing them at life-long risk for clinically-significant hyperthermia.

9 Nov 2010

Merrimack receives $2.44 million under QTDP program to support cancer research

Merrimack Pharmaceuticals was awarded $2.44 million to support research on 10 of its cancer programs through the Qualifying Therapeutic Discovery Project, a grant program created as part of the Patient Protection and Affordable Care Act of 2010 to advance research in areas of unmet medical need.

9 Nov 2010

Medisafe 1 website highlights ways to prevent incorrect medications

Medisafe 1 Technologies Corp. a developer of patented technologies that physically prevent the unauthorized administration of prescription medications, announced today that the company has uploaded a product presentation on the company's new website.

9 Nov 2010

Food security conference in The Hague concludes with suggestions for U.N. climate negotiations to incorporate agriculture

Participants in a five-day food security meeting at The Hague "urged U.N. climate negotiators Friday to consider agriculture when drawing up strategies to fight climate change," the Canadian Press reports.

9 Nov 2010

Letter asks G20 leaders to support financial transactions tax to help developing countries

G20 leaders meeting in Seoul this week are being asked to commit to plans for a 'Robin Hood Tax' on financial transactions, politics.co.uk reports.

9 Nov 2010

Medical News

European study indicates cardiovascular deaths can be avoided through better preventative care

Smoking increases risk of breast cancer progression in multiethnic women with breast cancer

New approach to treat castration resistant prostate cancer

Genetic region linked to survival in patients with advanced bowel cancer

New TB-drugome may help identify protein targets for tuberculosis

Sugar-sweetened drinks can increase gout risk in women

Chemotherapy for breast cancer does more harm than good

EVP-6124 receptor acts as co-agonist with ACh to enhance cognition

Valley Anesthesiology Consultants' mobile services division receives AAAHC accreditation

Colcrys safe for treating gout flares

Study discovers role of Vav1 oncogene in several cancers

Combination of optical and x-ray imaging may improve diagnostic accuracy of breast screening

Scientists develop nanobioconjugate drug to target brain tumor

Genta commences tesetaxel Phase 2b clinical trial as 1st-line chemotherapy for metastatic breast cancer

SIMPONI injection improves inflammation, structural damage in RA patients

Study confirms defect in sweat gland function as disease biomarker for XLHED

Merrimack receives $2.44 million under QTDP program to support cancer research

Medisafe 1 website highlights ways to prevent incorrect medications

Food security conference in The Hague concludes with suggestions for U.N. climate negotiations to incorporate agriculture

Letter asks G20 leaders to support financial transactions tax to help developing countries

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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