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Lack of awareness contributes to under-reporting of adverse drug reactions

Around 75% of Australians have experienced a bad reaction to a medication, but fewer than half have reported it to a doctor or the Therapeutic Goods Administration (TGA), a new survey has found.

24 Sep 2024

Inadequate staffing in surgical wards linked to adverse outcomes

A new paper in the British Journal of Surgery, published by Oxford University Press, shows that nursing shortages result in longer hospital stays and worse patient outcomes, including higher mortality.

24 Sep 2024

New drug combo shows promise for deeper remission in chronic leukemia

Researchers leading the SWOG S1712 clinical trial have found that adding ruxolitinib to standard tyrosine kinase inhibitor (TKI) treatment for patients with chronic-phase chronic myeloid leukemia (CP-CML) significantly increased the percentage of patients who had a molecular response deep enough to warrant discontinuing treatment.

24 Sep 2024

Age-related differences in financial decision-making and social influence

Older people are more likely to be influenced by the impulsive financial preferences of others than their younger counterparts, according to a new study.

24 Sep 2024

Neuroactive drugs show promising anti-glioblastoma effects in preclinical trials

Study explores the potential to repurpose neuroactive drugs, originally approved for neurological disorders, for the treatment of glioblastoma. Vortioxetine, an antidepressant, showed promising anti-glioblastoma activity, significantly reducing tumor size in preclinical trials.

24 Sep 2024

Simple intervention can prevent lifelong disability in premature babies

Giving women at risk of premature birth a simple magnesium sulphate infusion (or 'drip') can prevent their babies from developing cerebral palsy, a recent Cochrane review has confirmed. The drug itself costs approximately £5 (~$6.50) per dose in England, and requires hospital admission with experienced staff to administer the drug safely to the mother.

24 Sep 2024

Wastewater surveillance detects influenza and H5 viruses from human and animal sources

Wastewater surveillance reveals influenza A and H5 subtype detections, providing critical insights into public health risks from both human and animal sources during the ongoing HPAI A(H5N1) outbreak.

24 Sep 2024

Medicare coverage for obesity drug raises questions

Millions of older Americans with obesity could potentially get Medicare's help with the hefty price of a weight-loss medication in order to reduce their high risk of heart problems.

23 Sep 2024

Study highlights urgent need for improved care for schizophrenia

New research finds that adults with schizophrenia spectrum disorders have high rates of comorbid mental and substance use disorders and significant social and economic disadvantages, and only 26% received minimally adequate treatment.

23 Sep 2024

Deep learning tool offers new insights into protein function and disease

A University of Missouri researcher has created a computer program that can unravel the mysteries of how proteins work together -; giving scientists valuable insights to better prevent, diagnose and treat cancer and other diseases.

23 Sep 2024

Human challenge study reveals lasting cognitive decline after mild COVID-19

Researchers from the UK conducted the first human challenge study of SARS-CoV-2, revealing long-lasting cognitive deficits in unvaccinated participants infected with the virus, especially in memory and executive function.

23 Sep 2024

Space conditions disrupt rhythmic function of bioengineered heart tissues

Johns Hopkins Medicine scientists who arranged for 48 human bioengineered heart tissue samples to spend 30 days at the International Space Station report evidence that the low gravity conditions in space weakened the tissues and disrupted their normal rhythmic beats when compared to earth-bound samples from the same source.

23 Sep 2024

Brazil nuts reduce inflammation and improve gut health in women on restricted diets

Brazil nut consumption in an energy-restricted diet significantly reduced inflammation and improved intestinal permeability in overweight/obese women, likely due to selenium’s anti-inflammatory properties.

23 Sep 2024

Medicaid patients less likely to receive prenatal heart defect diagnoses

Patients insured by Medicaid are less likely to get prenatal diagnosis of heart defects than those with private insurance, and this disparity can be partly attributed to lower rates of 20-week ultrasound in pregnant people with public insurance, according to a study led by Ann & Robert H. Lurie Children's Hospital of Chicago in collaboration with Advocate Christ Children's Hospital. The study was published in the journal Prenatal Diagnosis.

23 Sep 2024

UChicago Medicine implants first Revi neuromodulation device to improve bladder control

UChicago Medicine has become the first medical center in Illinois to implant the Revi neuromodulation device, an exciting new treatment option that could offer relief for patients with urinary urgency incontinence (UUI).

23 Sep 2024

Study aims to uncover sex-specific causes of shoulder pain in wheelchair users

Josh Leonardis received funding from the Eunice Kennedy Shriver National Institute of Child Health and Human Development of the National Institutes of Health to study why female manual wheelchair users experience shoulder pain and pathology at greater rates than males.

23 Sep 2024

Transparent capsules in inhalers improve medication delivery for chronic airway diseases

This study examined whether patients with non-reversible chronic airway disease using a transparent capsule in single-dose dry powder inhalers affects the amount of medication delivered.

23 Sep 2024

Remote monitoring program improves blood pressure control in underserved patients

Underserved communities are at higher risk for uncontrolled high blood pressure (hypertension), which can lead to heart disease and higher death rates.

23 Sep 2024

Just one egg daily reduces nutrient gaps among U.S. adolescents, study shows

Over 60% of U.S. adolescents are at risk of nutrient inadequacy, but adding just one egg per day can improve their intake of key nutrients, especially for food-insecure teens.

23 Sep 2024

New model identifies cancer patients at high risk for ER visits during clinical trials

Investigators from the SWOG Cancer Research Network have developed and validated a risk prediction model for identifying which patients with advanced cancer who are enrolled to clinical trials are at highest risk for unplanned emergency room (ER) visits and hospital stays.

23 Sep 2024