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Chemotherapy-induced anemia increases risk of local breast cancer recurrence

Patients with breast cancer who developed anemia during chemotherapy had nearly three times the risk of local recurrence as those who did not, according to a study published in the April 1 issue of Clinical Cancer Research¸ a journal of the American Association for Cancer Research.

2 Apr 2008

Catheter repair of mitral valve improves heart size, symptoms

A catheter-mounted device that acts like a clothespin to clip together the flaps of a leaky heart valve is not only reducing the abnormal backflow of blood from the left ventricle to the left atrium, it is helping to shrink the enlarged, overworked heart and relieving symptoms of fluid overload - all without open-chest surgery.

2 Apr 2008

Distinguishing non-TB pulmonary disease from TB

A diagnostic kit shows new promise for distinguishing between tuberculosis (TB) and its infections from disease caused by related mycobacteria family, which mimic TB and other lung disease in symptoms but require distinctly different clinical treatments.

2 Apr 2008

Tai Chi improves control of type 2 diabetes

Tai Chi exercises can improve the control of type 2 diabetes, suggests a small study, published ahead of print in the British Journal of Sports Medicine.

1 Apr 2008

New breakthrough discovery on TB

Medical scientists from the University of Leicester, together with colleagues from St Georges, University of London, funded principally by the Medical Research Council (MRC) and The Wellcome Trust, have published details of a new breakthrough discovery on TB.

1 Apr 2008

Why synthetic estrogens wreak havoc on reproductive system

Researchers at Yale School of Medicine now have a clearer understanding of why synthetic estrogens such as those found in many widely-used plastics have a detrimental effect on a developing fetus, cause fertility problems, as well as vaginal and breast cancers.

1 Apr 2008

HIV-positive women in the United States face strikingly high levels of stigma

HIV-positive women in the United States face strikingly high levels of stigma, according to survey results released today by amfAR, The Foundation for AIDS Research.

1 Apr 2008

New type of imaging system illuminates tumors to nearly one-trillionth of a meter

Doctors' quest to see what is happening inside a living body has been hampered by the limits on detecting tiny components of internal structures and events.

1 Apr 2008

Study results on novel drug-eluting stent coated with a biodegradable polymer

"Real-world" use of a novel drug-eluting stent coated with a biodegradable polymer is associated with good clinical outcomes, according to one-year data from a large international registry.

1 Apr 2008

Racial differences in response to bowel cancer genetic risk factor

Scientists have for the first time discovered that people with the same cancer susceptibility genes respond differently depending on their race.

1 Apr 2008

Poor kids more likely to be seriously injured on roads as rich kids

Rates of serious injury among child pedestrians in poor areas of England are four times as high as those among children in affluent areas, finds research published ahead of print in the Archives of Disease in Childhood.

1 Apr 2008

Exercise delays onset of Huntington’s in mouse model

The simple act of running in an exercise wheel delays the onset of some symptoms of Huntington's disease in a mouse model of the fatal human disorder according to research published in the open-access journal BMC Neuroscience.

1 Apr 2008

A randomised, blinded, placebo-controlled trial in dementia patients continuing or stopping neuroleptics

Results of a randomised trial published in PLoS Medicine show no benefit in cognitive or neuropsychiatric outcomes from continuing neuroleptic drugs in patients with Alzheimer's disease.

1 Apr 2008

New research shows benefits of ultrasound contrast agents outweigh potential risk to heart patients

A Saint Louis University cardiologist called upon the U.S. Food and Drug Administration (FDA) today to reconsider a strong warning it recently placed on a diagnostic tool, stating that the warning could prevent doctors from detecting life-threatening cardiac events.

1 Apr 2008

New insight into the menopause

Insight into why females of some species undergo menopause while others do not has proven elusive despite an understanding of the biological mechanisms behind the change.

1 Apr 2008

New genetic clues to diabetes

An international team that included scientists from the National Human Genome Research Institute (NHGRI), part of the National Institutes of Health (NIH), today reported it has identified six more genetic variants involved in type 2 diabetes, boosting to 16 the total number of genetic risk factors associated with increased risk of the disease.

1 Apr 2008

Lung transplants not dangerous for children with cystic fibrosis, after all

Responding to a study published in the New England Journal of Medicine, which concluded that lung transplants were harmful for children with cystic fibrosis, articles published in the latest issue of Pediatric Transplantation refute the conclusions and argue that the highly influential research was severely flawed.

1 Apr 2008

Eli Lilly starts trial of treatment of mild to moderate Alzheimer's disease

Eli Lilly and Company has announced the start of a Phase III clinical trial studying LY450139, an investigational gamma secretase inhibitor for the treatment of mild to moderate Alzheimer's disease.

1 Apr 2008

Disappointing resuts for pimecrolimus, investigational anti-restenosis drug

A new medication that researchers had hoped would reduce the risk of arterial renarrowing after stenting has turned in a disappointing performance in a multicenter clinical trial, but the multi-reservoir stent that was used to deliver the drug is still considered promising.

1 Apr 2008

Researchers discover how HIV can hide in cells

Researchers have discovered how Human Immunodeficiency Virus (HIV), which causes AIDS, can hide itself in our cells and dodge the attention of our normal defences, scientists heard at the Society for General Microbiology's 162nd meeting being held this week at the Edinburgh International Conference Centre.

1 Apr 2008