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Tau protein expression predicts breast cancer survival in an unexpected way

Expression of the microtubule-binding protein Tau is not a reliable means of selecting breast cancer patients for adjuvant paclitaxel chemotherapy, according to research led by The University of Texas M. D. Anderson Cancer Center.

14 Dec 2008

Cymbalta (duloxetine HCl) shown to delay new episodes of depression

New data suggest that Cymbalta (duloxetine HCl) 60 mg to 120 mg once daily delayed the onset of a new episode of depression in patients who had previously responded to the medication and who had recurrent depressive disorder, defined in the study as those patients who experienced at least three depressive episodes in the previous five years, compared with placebo (p < .001).

14 Dec 2008

Study reveals clues to how we forget over short-term

Even though forgetting is such a common occurrence, scientists have not reached a consensus as to how it happens.

14 Dec 2008

Doxil and docetaxel combination treatment delays disease progression in metastatic breast cancer

Results from a Phase 3 study show that patients with metastatic breast cancer who were treated previously with an anthracycline in the adjuvant setting experienced a significant improvement in time to disease progression (TTP) and overall response rates after receiving a combination of DOXIL (doxorubicin HCl liposome injection) and docetaxel as compared to docetaxel alone.

14 Dec 2008

Exercise can relieve symptoms of peripheral artery disease

You probably know that poor diet and lack of exercise can lead to dangerous deposits of fatty plaques in arteries.

14 Dec 2008

Single adult stem cell can self-renew in a mammal

The first demonstration that a single adult stem cell can self-renew in a mammal was reported at the American Society for Cell Biology (ASCB) 48th Annual Meeting, Dec. 13-17, 2008 in San Francisco.

14 Dec 2008

Research aims to reduce scarring from heart attacks

A heart damaged by heart attack is usually broken, at least partially, for good.

14 Dec 2008

Exparel (DepoBupivacaine) shows promise in hernia repair

A Phase II trial of a single intraoperative administration of Exparel (DepoBupivacaine) resulted in significantly reduced pain with activity in the first 8 to 24 hours following surgery, when pain is generally greatest, compared to conventional treatment.

14 Dec 2008

Planned safety analysis of a breast cancer prevention study reveals encouraging news for Exemestane

An interim analysis of a breast cancer prevention study using exemestane (Aromasin) finds an "acceptable" level of bone loss.

14 Dec 2008

Paliperidone palmitate shows positive results for treatment of schizophrenia

Paliperidone palmitate, an investigational long-acting therapy (LAT) demonstrated statistically significant symptom control compared with placebo according to the results of a 13-week study.

14 Dec 2008

Parkinson's disease can also affect changes in thought, behavior and judgment

Parkinson's disease affects 6.3 million people worldwide. While the disease is recognized for its profound effects on movement, up to 40 percent of Parkinson's disease patients also develop changes in thought, behavior and judgment.

14 Dec 2008

Zometa (zoledronic acid) shown to enhance chemotherapy in reducing breast tumor size

New data released demonstrates that the addition of Zometa (zoledronic acid) injection to standard chemotherapy before breast cancer surgery reduces the size of breast tumors more effectively than chemotherapy alone in women with early-stage disease.

14 Dec 2008

CDC report details child and teen injuries / fatalities in the U.S.

An estimated 55 million children and teens from birth to age 19 were treated in emergency departments for unintentional injuries from 2001 to 2006, according to a new report released today by the Centers for Disease Control and Prevention (CDC).

14 Dec 2008

NACCHO to donate up to one million doses of FluMist

The National Association of County and City Health Officials (NACCHO) has announced a donation of up to one million doses of FluMist (Influenza Virus Vaccine Live, Intranasal) by MedImmune in a partnership aimed at increasing influenza awareness and vaccinations in underserved communities and populations.

14 Dec 2008

Carbon nanotube sensors for cancer drugs

MIT engineers have developed carbon nanotubes into sensors for cancer drugs and other DNA-damaging agents inside living cells.

14 Dec 2008

Having dense breasts increases breast cancer risk

Having dense breasts - areas that show up light on a mammogram - is strongly associated with increased breast cancer risk, but "why" remains to be answered.

14 Dec 2008

Postmenopausal patients being considered for tamoxifen therapy should be tested for CYP2D6 gene deficiency

Findings from a new study have prompted Mayo Clinic researchers to recommend CYP2D6 gene testing for postmenopausal women about to begin tamoxifen therapy.

14 Dec 2008

Researchers develop universal influenza vaccine for animals

A University of Maryland-led science team has developed a universal influenza vaccine for animals that may help prevent or delay another human flu pandemic.

14 Dec 2008

Discovery of seven new sites in the human genome found to influence obesity

In one of the largest studies of its kind, a multinational team led by scientists from deCODE genetics has reported the discovery of common variations at seven new sites in the human genome found to influence obesity.

14 Dec 2008

Promising clinical trial for Progeria "premature aging" disease

One of the fastest translations of a basic research discovery into a promising clinical trial for an "untreatable" and fatal disorder will be discussed publicly for the first time by the key players in this remarkable research story, on Sunday, Dec. 14, at the American Society for Cell Biology (ASCB)'s annual meeting in San Francisco.

14 Dec 2008