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Peptide therapy used to prevent progression of Parkinson's

Researchers have successfully used a peptide to reverse biochemical, cellular and anatomical changes that occur in the brains of mice with Parkinson's disease (PD), and report success in preventing the disease from progression.

21 Nov 2007

First genome sequence of XDR strain of the bacterium Mycobacterium tuberculosis

An international collaboration led by researchers in the US and South Africa today announced the first genome sequence of an extensively drug resistant (XDR) strain of the bacterium Mycobacterium tuberculosis, one linked to more than 50 deaths in a recent tuberculosis (TB) outbreak in KwaZulu-Natal, South Africa.

21 Nov 2007

New model to predict the spread of emerging diseases

A new model to predict the spread of emerging diseases has been developed by researchers in the US, Italy, and France.

21 Nov 2007

Scientists identify key nerve navigation pathway

Newly launched nerve cells in a growing embryo must chart their course to distant destinations, and many of the means they use to navigate have yet to surface.

21 Nov 2007

Pregnant women pass on the effects of smoking

Smoking during pregnancy has many adverse effects on fetal development.

21 Nov 2007

Oral drug sets a new survival standard for bone marrow cancer

Findings from two large, international clinical trials show "unprecedented" survival for patients with multiple myeloma, a blood cancer that occurs in the blood-making cells of bone marrow.

21 Nov 2007

Pediatric pediatric pulmonary expert comments on study of lung transplants for cystic fibrosis

Commenting on a study of lung transplantation for children with cystic fibrosis, a leading pediatric pulmonologist calls the study “startling” in an editorial in this week's New England Journal of Medicine that accompanies the study.

21 Nov 2007

Naturally occurring brain chemical acetylcholine enhances visual processing

Neuroscientists at New York University have found that a naturally occurring chemical in the brain can enhance visual processing and suggest that this chemical may represent part of the biological basis of visual attention.

21 Nov 2007

New study finds blood-spinal cord barrier compromised in mice with ALS

The blood-spinal cord barrier is functionally impaired in areas of motor neuron damage in mice modeling amyotrophic lateral sclerosis (ALS), report researchers at the University of South Florida Center for Aging and Brain Repair.

21 Nov 2007

New Zeiss microscope peers into secret lives of cells

“See those white sparks?” asks Kirk Czymmek, as he points to the video on his computer screen of a highly magnified heart cell in action.

21 Nov 2007

New discoveries about nitric oxide can provide drugs for schizophrenia

Problems with memory and social function in patients with schizophrenia may result from an imbalance in the brain’s nitric oxide system.

21 Nov 2007

Molecular foreman discovered for brain wiring

Researchers have identified a master regulatory molecule that is responsible for triggering the remodeling of neuronal connections that is critical for learning.

21 Nov 2007

Mapping the selective brain

Researchers have added a new piece to the puzzle of how the brain selectively amplifies those distinctions that matter most from the continuous cascade of sights, sounds, and other sensory input.

21 Nov 2007

Lung transplants do more harm than good to children with cystic fibrosis

Lung transplantation, the therapy almost every cystic fibrosis patient (CF) considers at some point to prolong survival, rarely helps children with the disease live longer and, in fact, often increases their risk of dying, University of Utah researchers conclude in the most extensive study of the issue to date.

21 Nov 2007

Is there an objective biological basis for the experience of beauty in art?

Or is aesthetic experience entirely subjective? This question has been addressed in a paper published in this week's PLoS ONE, Cinzia Di Dio, Emiliano Macaluso and Giacomo Rizzolatti. The researchers used fMRI scans to study the neural activity in subjects with no knowledge of art criticism, who were shown images of Classical and Renaissance sculptures.

21 Nov 2007

How can we know early who will benefit from tumor target therapy?

The precise tailoring of tumor target treatment for patients with cancer is an unmet challenge.

21 Nov 2007

GlaxoSmithKline to acquire Reliant Pharmaceuticals

GlaxoSmithKline and Reliant Pharmaceuticals Inc. have announced that they had reached an agreement under which Reliant will be acquired by GSK for $1.65 billion (800 million pounds Sterling) in cash.

21 Nov 2007

FDA approves formulations of Zyrtec (cetirizine HCl) for nonprescription use

The U.S. Food and Drug Administration has approved tablet, chewable tablet, and syrup formulations of Zyrtec (cetirizine HCl) for nonprescription use.

21 Nov 2007

Moderate, long-term pain medication use does not impair a person's ability to drive safely

Moderate, long-term pain medication use does not impair a person's ability to drive safely, according to a study by Dr. Asokumar Buvanendran, associate professor, Department of Anesthesiology at Rush University Medical Center, Chicago.

21 Nov 2007

Lenalidomide - dexamethasone combination effective against multiple myeloma

Pairing a new thalidomide derivative with a steroid slows progress of multiple myeloma, an incurable bone marrow cancer, and prolongs the lives of patients who have relapsed from previous treatment, researchers report in the Nov. 22 New England Journal of Medicine.

21 Nov 2007