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Trial of new biologic agent to treat psoriatic arthritis

Psoriatic arthritis affects about 11 percent of patients with psoriasis.

8 Apr 2009

Multifocal lung cancers appear to originate from single cancer clone

Multiple, anatomically distinct lung cancer tumors may frequently arise from a single cancer cell, according to a retrospective analysis of patient tumor samples published in the April 7 online issue of the Journal of the National Cancer Institute.

8 Apr 2009

More intensive treatment not associated with better outcomes in early bladder cancer

Patients with early bladder cancer who receive more intensive treatment within the first two years of diagnosis do not appear to have better survival than patients who receive less intensive treatment, according to a retrospective analysis published in the April 7 online issue of the Journal of the National Cancer Institute.

8 Apr 2009

Aggressive treatment for early stage bladder does not improve survival

Despite enduring more invasive tests and medical procedures, patients who were treated aggressively for early stage bladder cancer had no better survival than patients who were treated less aggressively.

8 Apr 2009

Mexican health care program has reduced health care costs

In results from the largest health policy study of its kind, a Mexican health care program created in 2003 has been found effective in reducing crippling health care costs among poorer households.

8 Apr 2009

Discovery of mechanism of cell type-specific signaling in tumor development

Mayo Clinic researchers have discovered the mechanisms behind two key checkpoints in cell growth and development - factors that may ultimately allow investigators to benchmark progression of tumor cells or stop them from further development.

8 Apr 2009

Transplantation immunity breakthrough

Australian scientists have made a discovery that may one day remove the need for a lifetime of toxic immunosuppressive drugs after organ transplants.

8 Apr 2009

Research finds insulin plays a key role in suppressing levels of glucagon

Researchers at the Joslin Diabetes Center have shown for the first time that insulin plays a key role in suppressing levels of glucagon, a hormone involved in carbohydrate metabolism and regulating blood glucose levels.

8 Apr 2009

Classroom-based intervention reduces children's viewing of violent TV

A team of Oregon State University researchers has successfully implemented a classroom-based intervention that reduces the amount of violent TV that children watch.

8 Apr 2009

Intercell starts trial for Streptococcus pneumoniae vaccine candidate

Intercell AG has announced that a Phase I clinical trial with the company's vaccine candidate IC47 to prevent disease caused by the bacterium Streptococcus pneumoniae has started.

8 Apr 2009

Diets high in fat and protein are most dangerous

It's basically a given that diets loaded with fat can lead to considerable health problems.

8 Apr 2009

HIV virus may have become more virulent

Damage to patients' immune systems is happening sooner now than it did at the beginning of the HIV epidemic, suggesting the virus has become more virulent, according to a new study in the May 1, 2009 issue of Clinical Infectious Diseases, now available online.

8 Apr 2009

Growth factor TGF-beta helps maintain health of retinal blood vessels

Scientists at Schepens Eye Research Institute have found that the growth factor known as TGF-beta is essential to the health of blood vessels in the retina and that blocking it can cause retinal dysfunction.

8 Apr 2009

Genetic risk factors play role in autoantibody-negative rheumatoid arthritis

During the past few years, several new genetic risk factors for rheumatoid arthritis (RA) have been identified.

8 Apr 2009

Gene delivery appears safe for regenerating tooth-supporting gum tissue

Scientists at the University of Michigan have developed a method of gene delivery that appears safe for regenerating tooth-supporting gum tissue---a discovery that assuages one of the biggest safety concerns surrounding gene therapy research and tissue engineering.

8 Apr 2009

New nanostructured biosensors

Research and industry are increasingly exploiting the potential of aptamers.

8 Apr 2009

FDA approves label change for non-invasive fibroid treatment

InSightec Ltd. has announced that the U.S. Food and Drug Administration (FDA) approved a label change for the company's ExAblate 2000 MR-guided Focused Ultrasound (MRgFUS) system for the treatment of women with non-hysteroscopically resectable uterine fibroids.

8 Apr 2009

Inflammatory chemokine may explain diseases that come with obesity

An inflammatory factor already linked to several diseases, including pulmonary disease, lung cancer, and arthritis, may also be responsible for the insulin resistance that comes with obesity, according to a new study published in the April issue of Cell Metabolism.

8 Apr 2009

Discovery of marker for colon stem cells could shed light on tumor growth

Cancer researchers led by Bruce Boman, M.D., Ph.D. director of Cancer Genetics and Stem Cell Biology at the Helen F. Graham Cancer Center of the Christiana Care Health System, and a faculty member at the University of Delaware, have discovered an enzyme common to both normal and malignant colon stem cells that will assist scientists searching for a cure for colon cancer.

8 Apr 2009