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Is esomeprazole the best choice for reflux esophagitis patients?

In patients with gastroesophageal reflux disease (GERD), esomeprazole, has demonstrated pharmacological and clinical benefits beyond those seen with the other proton pump inhibitors (PPIs).

2 Apr 2009

Eating a low energy density diet can offset influence of obesity gene

Children who carry a gene strongly associated with obesity could offset its effect by eating a low energy density diet, according to new research from UCL (University College London) and the University of Bristol published in PLoS ONE.

2 Apr 2009

Multiple childhood maltreatments lead to underage binge drinking

Researchers from Boston University found that multiple types of child maltreatment are robust risk factors for underage binge drinking based on a national multi-year study that explored the influence of social environment on the health of adolescents.

2 Apr 2009

Inactivity of proteins behind longer shelf life when freezing

Frozen biological material, for example food, can be kept for a long time without perishing.

2 Apr 2009

High novelty-seeking and low avoidance of harm contribute to alcohol dependence

Personality factors can influence the development of alcohol dependence (AD).

2 Apr 2009

Two or more alcoholic drinks a day may increase pancreatic cancer risk

Men and women who consume two or more alcoholic drinks a day could increase their risk of developing pancreatic cancer, according to a study published in Cancer Epidemiology, Biomarkers and Prevention , a journal of the American Association for Cancer Research.

2 Apr 2009

FDA warning letter to Genzyme related to the Allston facility

BioMarin Pharmaceutical Inc. has announced that the FDA warning letter issued to Genzyme addressing deficiencies related to Genzyme's Allston Landing manufacturing facility during an inspection performed in September and October 2008 has no foreseeable impact on the supply of Aldurazyme.

2 Apr 2009

FDA provides positive review of InNexus Biotechnology development plan for lead preclinical candidate

InNexus Biotechnology Inc. has announced the United States Food & Drug Administration (FDA) has completed its comprehensive review of the development plans for InNexus' lead preclinical candidate, DXL625 (CD20) for the prospective treatment of Non-Hodgkin's Lymphoma (NHL) and/or Chronic Lymphocytic Leukemia (CLL).

2 Apr 2009

FDA clears Cellectar's IND application for drug candidate

Cellectar, Inc., a privately held radiopharmaceuticals company that designs and develops products to detect, treat and monitor human cancers, has announced that the U.S. Food and Drug Administration (FDA) has cleared the Company's Investigational New Drug (IND) application for its (131)I-CLR1404 drug candidate for testing in patients with advanced solid malignancies.

2 Apr 2009

Urban design and fast-food density affect residents' weight and waist size

In a research article published recently by the American Journal of Epidemiology, Oregon Research Institute (ORI) scientist Fuzhong Li, Ph.D., and colleagues show that a high-density of fast food outlets was associated with an increase of 3 pounds in weight and .8 inches in waist circumference among neighborhood residents who frequently ate at those restaurants.

2 Apr 2009

Drugs that act on 'fasting signal' may curb insulin resistance in obese

A report in the March issue of Cell Metabolism , a Cell Press publication, has found that a signal known to play a role during fasting also switches on early in the fat tissue of obese mice as they progress toward type 2 diabetes.

2 Apr 2009

Electroacupuncture protects acetylsalicylic acid-induced acute gastritis in rats

Nonsteroidal anti-inflammatory drugs (NSAIDs) are widely used as anti-inflammatory and analgesic agents.

2 Apr 2009

Researchers discover structure-building role for 2 non-coding RNAs

Most of the DNA in the nucleus of each of our cells is converted into RNA, but only a small fraction of these RNA molecules serve as coding templates for the synthesis of proteins.

2 Apr 2009

Colonoscopy versus virtual colonoscopy

Today, patients have a wide selection of colorectal cancer screening exams from which to choose, unlike with other types of cancers.

2 Apr 2009

Certain combined medications following heart attack may increase risk of death

Following an acute coronary syndrome such as a heart attack or unstable angina, patients who receive a medication to reduce the risk of gastrointestinal bleeding that may be associated with the use of the antiplatelet drug clopidogrel and aspirin have an increased risk of subsequent hospitalization for acute coronary syndrome or death, according to a study in the March 4 issue of JAMA, the Journal of the American Medical Association.

2 Apr 2009

Boston Scientific announces Japanese launch of Taxus Liberte drug-eluting stent system

Boston Scientific Corporation has announced the launch of its TAXUS Liberte Paclitaxel-Eluting Coronary Stent System in Japan.

2 Apr 2009

Bionovo announces publication of positive phase 2 trial results for Menerba

Bionovo, Inc. has announced the online publication of a peer-reviewed article in the journal, Menopause, reporting Menerba(TM) (formerly MF101) is well tolerated, safe and effective for the treatment of vasomotor symptoms (hot flashes and night sweats) associated with menopause.

2 Apr 2009