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Discovery of potential oral treatment for diabetes

Research in the Department of Biology at the Faculty of Science and Science Education of the University of Haifa has discovered a substance that may become an oral treatment for diabetes and its complications.

28 Dec 2007

NIEHS awards $6.8 million DISCOVER grants

The National Institute of Environmental Health Sciences (NIEHS), part of the National Institutes of Health, is awarding a total of $6.8 million for the first year of funding to three new research centers called DISCOVER - Disease Investigation Through Specialized Clinically-Oriented Ventures in Environmental Research.

28 Dec 2007

New way to screen for chagas disease in children

A new targeted screening strategy could make the diagnosis and treatment of Chagas disease more feasible in low-resource settings, concludes a new study, publishing on December 26, 2007, in the open-access journal PLoS Neglected Tropical Diseases.

28 Dec 2007

New drug targets may fight tuberculosis and other bacterial infections in novel way

Over the course of the 20th Century, doctors waged war against infectious bacterial illness with the best new weapon they had: antibiotics.

28 Dec 2007

Personalized medicine will alter treatment of genetic disorders

One of the nation's pre-eminent genetic researchers, Eric Hoffman, PhD, of Children's Research Institute at Children's National Medical Center, predicts that in relatively short order, medicine's next innovation--individualized molecular therapies--will have the unprecedented ability to treat muscular dystrophies, and other disorders.

28 Dec 2007

Mutations in a protein called dynein may cause inherited neuropathy

Mutations in a protein called dynein, required for the proper functioning of sensory nerve cells, can cause defects in mice that may provide crucial clues leading to better treatments for a human nerve disorder known as peripheral neuropathy, which affects about three percent of all those over age 60.

28 Dec 2007

Neglected tropical diseases, lymphatic filariasis, trachoma, leishmaniasis, onchocerciasis and schistosomiasis

Though little known to most Americans, lymphatic filariasis, trachoma, leishmaniasis, onchocerciasis, schistosomiasis and other so-called neglected tropical diseases are responsible for severe health burdens, especially among the world's poorest people.

28 Dec 2007

Model developed that predicts molecular response of living cells to genetic or environmental change

Scientists at the Institute for Systems Biology (ISB), in collaboration with researchers from New York University (NYU), have developed a model which rapidly characterizes and accurately predicts the molecular-level, mechanistic response of a free-living cell to genetic and environmental changes.

28 Dec 2007

Light powered platinum more targeted and powerful than similar cancer treatments

Researchers from the Universities of Warwick, Edinburgh, Dundee and the Czech Republic's Institute of Biophysics have discovered a new light-activated platinum-based compound that is up to 80 times more powerful than other platinum-based anti-cancer drugs and which can use "light activation" to kill cancer cells in much more targeted way than similar treatments.

28 Dec 2007

Optimal therapy for U.S. hepatitis C patients

As reported recently in the journal Hepatology, WIN-R, a multicenter study of over 5,000 patients with hepatitis C virus (HCV) showed treatment with weight-based REBETOL ribavirin, USP) (RBV) in combination with pegylated interferon (PEG-IFN) alfa-2b achieved significantly higher rates of sustained virologic response (SVR) and lower relapse rates compared to combination therapy using a flat dose of RBV 800 mg/day. Superior response was found particularly in patients with the most difficult-to-treat form of the disease, genotype 1 HCV. Efficacy was consistent across all weight groups.

28 Dec 2007

High triglycerides, other cholesterol raise risk of stroke

People with high triglycerides and another type of cholesterol tested but not usually evaluated as part of a person's risk assessment have an increased risk of a certain type of stroke, according to research published in the December 26, 2007, online issue of Neurology, the medical journal of the American Academy of Neurology.

28 Dec 2007

Health improves for previously uninsured adults after receiving Medicare coverage

Previously uninsured adults who received Medicare coverage reported improvements in health, especially those with cardiovascular disease or diabetes, according to a study in the December 26 issue of JAMA: The Journal of the American Medical Association.

28 Dec 2007

Health coverage improves health and reduces major heart complications

As presidential candidates ramp up their primary campaigns, health care reform looms prominently among voters' main concerns.

28 Dec 2007

New information about how normal cells and cancer cells survive under stress

Scientists report that an evolutionarily conserved transcription factor may have both positive and negative effects on the growth of tumors, depending on whether or not the tumor cells have enough oxygen.

28 Dec 2007

New immune system discovery will help fight hay fever and other allergies

A mechanism which can lead to hay fever and other allergic reactions, by preventing the immune system from regulating itself properly, has been discovered by scientists.

28 Dec 2007

Fibrosis in the liver stopped and reversed by researchers

University of California, San Diego researchers have proven in animal studies that fibrosis in the liver can be not only stopped, but reversed.

28 Dec 2007

FDA approves Voluven for blood loss post surgery

The U.S. Food and Drug Administration has approved Voluven, an intravenous solution that prevents and treats a dangerous loss of blood volume, a condition that sometimes occurs during and after surgery.

28 Dec 2007

Copy number variation may stem from replication misstep

Genome rearrangements, resulting in variations in the numbers of copies of genes, occur when the cellular process that copies DNA during cell division stalls and then switches to a different genetic "template," said researchers at Baylor College of Medicine in Houston in a report that appears today in the journal Cell.

28 Dec 2007

Cone-beam breast CT compared to conventional mammography

Cone-beam breast CT provides exceptional tissue contrast and can potentially reduce examination time with comparable radiation dose to conventional 2D mammography, according to a new study by a team of researchers from the University of Texas M. D. Anderson Cancer Center in Houston.

28 Dec 2007