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Understanding diversity in disease - new routes to prevention, diagnosis and treatment

The Medical Research Council (MRC), the National Institute for Health Research (NIHR) and the health research departments in Northern Ireland, Scotland and Wales have launched a joint initiative of more than £6millon to identify small carefully defined groups of patients to help researchers detect, treat or prevent diseases.

14 Nov 2007

Low-fat answer to India's coronary crisis

First he devised a way for India's 11 million dairy farmers to improve milk production. Now Dr Suresh Gulati of the University of Sydney's Faculty of Veterinary Science is making milk healthier in a country where coronary heart disease is set to soar.

14 Nov 2007

EDMA calls for empowering people with diabetes

Type 2 diabetes and its complications are frequently diagnosed too late and the complications are often detected only at the time of diagnosis, concludes the European Parliament in its 2006 Written Declaration on Diabetes.

14 Nov 2007

Young men are just as affected by hair loss during cancer treatment

Research into young people's experiences of hair loss during cancer treatment has found it is a mistake to assume women will be more affected than men. Scientists analysing interviews with recovered young adult cancer patients enrolled in the DIPEx project found that young men were just as affected by chemotherapy-induced hair loss as young women.

14 Nov 2007

WaferGen and University of Pittsburgh to collaborate on SmartChip

WaferGen Biosystems, Inc. has announced that it has established a research collaboration with the University of Pittsburgh Medical School to have it serve as the alpha test site for WaferGen's SmartChip Real-Time PCR System.

14 Nov 2007

Avicena receives U.S. patent for compounds to treat Lou Gehrig's disease

Avicena Group, Inc. has announced that the United States Patent and Trademark Office (USPTO) has granted the Company U.S. Patent #7,285,573 for the use of the Company's proprietary drug candidates for the treatment of amyotrophic lateral sclerosis ("ALS" or "Lou Gehrig's Disease").

14 Nov 2007

Ultrasound may better classify ovarian tumors

Experts examining patterns in ultrasound images can more accurately classify ovarian tumors as benign or malignant than can pre-surgical blood tests, according to a study published online in the Nov. 13 Journal of the National Cancer Institute.

14 Nov 2007

UK hospitals short changing women with heart failure

Women with heart failure are less likely than men to receive recommended investigations and treatment, when admitted to hospital as an emergency, reveals an extensive UK survey, published ahead of print in the journal Heart.

14 Nov 2007

Tumour cells could be used to develop personalised light-activated cancer vaccines

Cancer tissue taken directly from patients could be used to produce a light-triggered vaccine to target and treat their own tumours, according to a study published in the British Journal of Cancer.

14 Nov 2007

New understanding of how bacteria survive in hostile environments

Using an innovative device with microscopic chambers, researchers from four institutions, including Johns Hopkins, have gleaned important new information about how bacteria survive in hostile environments by forming antibiotic-resistant communities called biofilms.

14 Nov 2007

Gene variants behind pancreatic stone formation

Stone formation is an important feature of chronic pancreatitis, especially tropical calcific pancreatitis (TCP), where the stones are large in size, highly irregular in shape and cause enormous tissue destruction.

14 Nov 2007

Telomerase enzyme structure provides significant new target for anti-cancer therapies

Inappropriate activation of a single enzyme, telomerase, is associated with the uncontrollable proliferation of cells seen in as many as 90 percent of all of human cancers. Since the mid-1990s, when telomerase was first identified in human tumors, scientists have eyed the enzyme as an ideal target for developing broadly effective anti-cancer drugs.

14 Nov 2007

STEP study of Merck's HIV vaccine to be unblinded

Merck & Co., Inc. and the HIV Vaccine Trials Network (HVTN) today announced that study volunteers in the STEP study of Merck's HIV vaccine (V520) will be told whether they received vaccine or placebo, and all study volunteers will be encouraged to continue to return to their study sites on a regular basis for ongoing risk reduction counseling and study-related tests.

14 Nov 2007

Sanofi Pasteur and Acambis to bring West Nile vaccine to market

Sanofi Pasteur, the vaccines division of sanofi-aventis Group, announced today that it has signed an exclusive global collaboration agreement with Acambis plc, for the development and marketing of a West Nile vaccine to help fight against this serious, life-altering and potentially fatal disease.

14 Nov 2007

GPRC5A gene found to be a tumor-suppressor for lung cancer

The GPRC5A gene, which is under-expressed in human lung cancer cells, suppresses lung tumors in mouse models and could provide a key to attacking lung cancer in humans, researchers at The University of Texas M. D. Anderson Cancer Center report in the Nov. 21 edition of The Journal of the National Cancer Institute.

14 Nov 2007

Pfizer and Nektar resolve outstanding Exubera contractual issues

Pfizer and Nektar Therapeutics have announced that the two companies have resolved all outstanding contractual issues in connection with Exubera and Nektar's innovative Next Generation Inhaled Insulin (NGI) product currently in Phase 1 clinical development.

14 Nov 2007

PET scans useful for some cancer treatment, but how do patients fare?

Positron emission tomography or PET scans can help clinicians diagnose and treat some cancers, but it is not clear yet whether the imaging technology helps people with cancer live longer and healthier lives, according to a comprehensive review by the U.K. National Health Service.

14 Nov 2007

number of cases of most vaccine-preventable diseases is at an all-time low

A comparison of illness and death rates for 13 vaccine-preventable diseases in the U.S., before and after use of the vaccine, indicates there have been significant decreases in the number of cases, hospitalizations and deaths for each of the diseases examined, according to a study in the November 14 issue of JAMA: The Journal of the American Medical Association.

14 Nov 2007

Hope on the horizon for hereditary angioedema sufferers

Although there is currently no treatment approved by the Federal Drug Administration (FDA) for acute attacks of hereditary angioedema (HAE) - a genetic disease causing swelling of extremities, face and internal organs that can be life-threatening - hope is on the horizon according to a team of experts presenting the latest research at the Annual Meeting of the American College of Allergy, Asthma and Immunology (ACAAI) in Dallas.

14 Nov 2007

La Jolla Institute for Allergy & Immunology to perform study on allergy molecular causes

A major study that will provide a new window into understanding and potentially treating allergies will be conducted by the La Jolla Institute for Allergy & Immunology (LIAI) under a $5 million federal contract.

14 Nov 2007