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Many patients with diabetes say burden of care rivals complications of disease

Many patients with diabetes say that the inconvenience and discomfort of constant therapeutic vigilance, particularly multiple daily insulin injections, has as much impact on their quality of life as the burden of intermediate complications, researchers from the University of Chicago report in the October 2007 issue of Diabetes Care.

27 Sep 2007

Experimental drug pertuzumab boosts survival in recurrent ovarian cancer

New clinical data showed an experimental drug called pertuzumab prolonged the survival time for women with recurrent ovarian cancer, a University of Alabama at Birmingham doctor said recently.

27 Sep 2007

Over use of multivitamins may raise prostate cancer risk

About a third of American adults take some type of multivitamin on a regular basis.

27 Sep 2007

Expertise modulates the perception of pain in others

Physicians apparently learn to “shut off” the portion of their brain that helps them appreciate the pain their patients experience while treating them and instead activate a portion of the brain connected with controlling emotions, according to new research using brain scans at the University of Chicago.

27 Sep 2007

DNA damage response confers a barrier for viral tumorigenesis

Kaposi's sarcoma herpesvirus (KSHV) is a human tumor virus and an etiological agent for Kaposi's sarcoma (KS).

27 Sep 2007

Dietary fatty acids may help prevent diabetes

Omega-3 fatty acids have long been touted for their heart-healthy and brain-boosting benefits. Consider cod liver oil, fortified infant formula and enriched eggs.

27 Sep 2007

Clinical trials for diabetes drugs should measure outcomes important to patients

Most clinical trials for new diabetes drugs do not consider the impact medication will have on a patient's quality of life or other outcomes that are important to patients, such as the risk of developing complications associated with diabetes, according to a Mayo Clinic commentary in the current issue of The Lancet.

27 Sep 2007

Clinical Trials Directive likely to turn Europe into the poor relation of clinical academic medicine

The Clinical Trials Directive, which came into force in May 2004 in order to create a harmonised framework for clinical drug research across Europe, is still hampering such research, according to new findings presented at the European Cancer Conference (ECCO 14).

27 Sep 2007

Climate change may increase heat-related deaths by 2050

While some uncertainty does exist in climate projections and future health vulnerability, overall increases in heat-related premature mortality are likely by the 2050s, according to a recent study by Columbia University's Mailman School of Public Health and soon to be published in the November 2007 issue of the American Journal of Public Health.

27 Sep 2007

Chemotherapy drug gemcitabine delays progression of operable pancreatic cancer

Barcelona, Spain: Giving pancreatic cancer patients the chemotherapy drug gemcitabine after surgery delays progression of the disease by about six months, according to new research by Japanese scientists.

27 Sep 2007

CDC awards $35 million to increase HIV testing opportunities

The Centers for Disease Control and Prevention has awarded $35 million in funding to state and local health departments to increase HIV testing opportunities among populations disproportionately affected by HIV, primarily African Americans.

27 Sep 2007

Biodel issued U.S. patent for VIAject and VIAtab

Biodel Inc. has announced the receipt of a notice of issuance from the United States Patent and Trademark Office (USPTO) for the Company's patent encompassing VIAject(TM) and VIAtab(TM), Biodel's two product candidates in clinical trials.

27 Sep 2007

Tumor cell receptor provides new therapeutic target

Working with a line of highly metastatic head and neck cancer cells, a research team at the Winship Cancer Institute and Emory University School of Medicine has found that a specific cell surface receptor present at very low levels in non-metastatic head and neck cancer cells.

27 Sep 2007

Evaluation of poly(glycerol adipate) nanoparticle uptake in an in vitro 3-D brain tumor co-culture model

A nanoparticle drug delivery system designed for brain tumor therapy has shown promising tumor cell selectivity in a novel cell culture model devised by University of Nottingham scientists.

27 Sep 2007

In vivo imaging of hydrogen peroxide with chemiluminescent nanoparticles

Most people think of hydrogen peroxide as a topical germ killer, but the medicine cabinet staple is gaining steam in the medical community as an early indicator of disease in the body.

27 Sep 2007

MicroPET-based biodistribution of quantum dots in living mice

A wide variety of experiments have shown that nanoscale quantum dots have the potential to detect early-stage cancer and even monitor the progress of anticancer therapies.

27 Sep 2007

Supramolecular chemistry on water-soluble carbon nanotubes for drug loading and delivery

In the quest to turn carbon nanotubes from nanoscale wonder into clinically useful drug and imaging agent delivery agents, researchers have often added polymer coatings to the outside of the nanotubes in order to render them biocompatible.

27 Sep 2007

Gold nanorods coated with multilayer polyelectrolyte as contrast agents for multimodal imaging

A growing body of research has demonstrated that gold nanorods can serve as extremely bright imaging agents.

27 Sep 2007

Organically modified silica nanoparticles with covalently incorporated photosensitizer for photodynamic therapy of cancer

Photodynamic therapy, in which light activates a chemical known as a photosensitizer, triggering the production of cell-killing reactive oxygen, has proven itself as an effective therapy for a limited number of cancers.

27 Sep 2007