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Neighbor clustering better identifies functionally related genes on the bacterial chromosome

The moment a bacterial pathogen makes contact with its host, its goal is simple: to infect.

1 Aug 2007

Bipolar disorder phenome database

A novel, free, public online database opening this week should greatly speed efforts to find genes linked to increase risk of bipolar disorder.

1 Aug 2007

Report reveals pregnancies exposed to accutane despite iPledge

Despite a mandatory program designed to prevent pregnant women from being exposed to the anti-acne medication Accutane and similar medications containing isotretinoin (a known teratogen or birth defect-causing agent), 122 pregnancies were exposed during the first year of the program, known as iPledge, a report revealed.

1 Aug 2007

U.S. blood donor pool smaller than previously thought

According to a new study in TRANSFUSION, the number of individuals in the U.S. who are eligible to donate blood may be smaller than previously believed, approximately 60 million fewer people.

1 Aug 2007

New way to predict how cells will respond to targeted drug therapies

Models based on this approach could help doctors make better treatment choices for individual patients, who often respond differently to the same drug, and could help drug developers identify the ideal compounds on which to focus their research.

1 Aug 2007

Nanoparticles may provide safe pain control on the battlefield

University of Michigan scientists have received a pilot grant of nearly $1.3 million from the Defense Advanced Research Projects Agency to test whether nanoparticles can solve a pressing problem in battle zones like Iraq: how to administer sustained, safe doses of the most effective painkillers to injured soldiers, long before they can reach expert medical help.

1 Aug 2007

Focused ultrasound treatment of uterine fibroids offers long term symptom relief

A noninvasive, outpatient treatment for noncancerous uterine tumors provides sustained relief from symptoms, according to a new Mayo Clinic led collaborative study.

1 Aug 2007

Pigs key to understanding antibiotic resistant bacteria

NSW Department of Primary Industries (NSW DPI) Immunology & Molecular Diagnostic Research Unit Team Leader, Dr James Chin, says it is commonly believed that each time an antibiotic is used only pathogens or disease-causing bacteria will be killed.

1 Aug 2007

Imaging technique accurate in aneurysm detection and therapy planning

Multidetector computed tomography (MDCT) angiography is highly accurate in depicting intracranial aneurysms, according to a study published in the August issue of Radiology.

1 Aug 2007

Huntington's disease study shows animal models on target

An international team of researchers has published a benchmark study showing that gene expression in several animal models of Huntington's Disease (HD) closely resembles that of human HD patients.

1 Aug 2007

HIV prevalence and predictors of infection in sex-trafficked Nepalese girls and women

A study by Harvard School of Public Health (HSPH) researchers of girls and women who were sex-trafficked from Nepal to India and then repatriated has found that 38 percent were HIV positive.

1 Aug 2007

High rates of posttraumatic stress disorder after war in Uganda

A survey of adults displaced by war in northern Uganda found high rates of posttraumatic stress disorder (PTSD) and depression, and that these individuals were more likely to favor violent means to end the conflict compared to persons without these symptoms, according to a study in the August 1 issue of JAMA, a theme issue on violence and human rights.

1 Aug 2007

Hallucinations in schizophrenia linked to brain area that regulates emotion and processes human voices

For the first time, researchers using magnetic resonance imaging (MRI) have found both structural and functional abnormalities in specific brain regions of schizophrenic patients who experience chronic auditory hallucinations, according to a study published in the August issue of Radiology.

1 Aug 2007

Tips for relief from gastroesophageal reflux disease

Are you suffering from heartburn? Heartburn can be a symptom of a serious problem called "gastroesophageal reflux disease," also known as GERD.

1 Aug 2007

Gold nanoparticles for cancer diagnosis

When it comes to searching out cancer cells, gold may turn out to be a precious metal.

1 Aug 2007

FDA Avandia recommendation welcomed by Endocrinologists

The American Association of Clinical Endocrinologists (AACE), along with the rest of the medical community, has watched with concern the debate regarding usage of GlaxoSmithKline's rosiglitazone (Avandia) in diabetes and the question of whether it increases cardiovascular risk.

1 Aug 2007

Child abuse and neglect increases when army parents deployed

Confirmed incidents of child abuse and neglect among Army families increase significantly when a parent is deployed to a combat zone, according to a new study by researchers at RTI International and the University of North Carolina at Chapel Hill School of Public Health.

1 Aug 2007