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Leg pain can mean peripheral arterial disease

David Dow thought he was having back problems, and that his legs were hurting as a result. As it turns out, that pain may have saved his life.

4 Apr 2007

Effectiveness of psychosocial treatments for bipolar disorder

This is a follow up study to one released last Thursday in the New England Journal of Medicine on the effects of antidepressants in the treatment of bipolar disorder. Both studies, called STEP-BD, were funded by the National Institute of Mental Health.

4 Apr 2007

Raman spectroscopy for faster body-fluid tests

University of Rochester researchers announce in the current issue of Applied Optics a technique that in 60 seconds or less measures multiple chemicals in body fluids, using a laser, white light, and a reflective tube.

4 Apr 2007

First national online autism registry

Kennedy Krieger Institute today announced the launch of the Interactive Autism Network (IAN) ,the first national online autism registry, at www.IANproject.org .

4 Apr 2007

People without health insurance more likely to forego routine physical exams

The lack of health insurance prompts people to forego routine physical exams and have a reduced awareness of cardiovascular risk factors and is associated with increased rates of stroke and death, researchers have concluded.

4 Apr 2007

New findings on hypoglycemic neuronal death

Treatment with insulin revolutionized the life of individuals with diabetes. However, because insulin acts to lower blood glucose levels, it can cause hypoglycemia (low levels of glucose in the blood), which, if prolonged, can lead to brain injury and coma.

4 Apr 2007

Insulin receptors play a critical role in promoting islet growth

A new Joslin-led study has identified the insulin receptor as an important protein that promotes islet cell growth in mice whose bodies are unable to use insulin properly, or are insulin resistant, a precursor to type 2 diabetes.

4 Apr 2007

Intensive psychotherapy most effective for treating bipolar depression

Patients taking medications to treat bipolar disorder are more likely to get well faster and stay well if they receive intensive psychotherapy, according to results from the Systematic Treatment Enhancement Program for Bipolar Disorder (STEP-BD), funded by the National Institutes of Health's (NIH) National Institute of Mental Health (NIMH).

4 Apr 2007

Weaker performance of siblings of children with autism spectrum disorder

Younger siblings of children with autism spectrum disorders do not perform as well on tests of social and communication development compared with siblings of children without developmental problems at ages as young as 12 months, according to a report in the April issue of Archives of Pediatrics & Adolescent Medicine, a theme issue on autism spectrum disorders.

4 Apr 2007

Treatment options for endometriosis

Jan Ruma's pain was getting worse, but she wrote it off as just a part of growing older and a normal side-effect of "that time of the month."

4 Apr 2007

Inhaled corticosteroids deserve further consideration for lung cancer chemoprevention

Among a group of mostly older male veterans suffering from chronic obstructive pulmonary disease (COPD), an illness that offers a greater susceptibility to lung cancer, researchers found that regular use of high dose inhaled corticosteroids (ICS) lowered the risk of developing lung cancer.

4 Apr 2007

TGF-beta found to be a major player in causing bronchopulmonary dysplasia

Researchers from Massachusetts General Hospital, in collaboration with scientists from the Genzyme Corporation, have identified a potential treatment for a chronic lung disease affecting premature infants.

4 Apr 2007

New device sniffs out olfactory disorders that could be an early warning of Alzheimer's, Parkinson's

The Sniff Magnitude Test (SMT), an invention of UC Psychology Professor Robert Frank and Professor Emeritus Robert Gesteland of the UC Department of Cell Biology, is now under further development with the WR Medical Electronics Company in Stillwater, Minn. The company will manufacture and market the test.

4 Apr 2007

New blood test to rapidly detect levels of radiation exposure

In the event of a nuclear or radiological catastrophe -- such as a nuclear accident or a "dirty bomb" -- thousands of people would be exposed to radiation, with no way of quickly determining how much of the deadly substance has seeped inside their bodies.

4 Apr 2007

Genelabs Tech reaches agreement with FDA on special protocol assessment for phase III trial of Prestara in lupus

Genelabs Technologies has announced that it has reached agreement with the U.S. Food and Drug Administration (FDA) on a Special Protocol Assessment (SPA) for a Phase III clinical trial of Prestara (prasterone) for treatment of systemic lupus erythematosus (lupus).

4 Apr 2007

Flexible electronic structures show potential for artificial muscles or biological tissues

Flexible electronic structures with the potential to bend, expand and manipulate electronic devices are being developed by researchers at the U.S. Department of Energy's Argonne National Laboratory and the University of Illinois at Urbana-Champaign.

4 Apr 2007

Computer model behaves like humans on visual categorization task

Computers can usually out-compute the human brain, but there are some tasks, such as visual object recognition, that the brain performs easily yet are very challenging for computers.

4 Apr 2007

Less children and teens taking antidepressants

The number of children and teenagers prescribed antidepressant medications appears to have decreased following public warnings about suicidal behavior potentially associated with the drugs, according to a report published in the April issue of Archives of General Psychiatry, one of the JAMA/Archives journals.

4 Apr 2007

FDA approves Twinrix

GlaxoSmithKline has announced that the U.S. Food and Drug Administration (FDA) has approved Twinrix [Hepatitis A Vaccine (Inactivated) and Hepatitis B (Recombinant) Vaccine], for an accelerated dosing schedule that consists of three doses given within three weeks followed by a booster dose at 12 months.

4 Apr 2007