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New mathematical model of sepsis

A new mathematical model of sepsis can help predict deaths, discharges, and disease progression in hospital patients with this serious bacterial blood infection. It's hoped the model, described in the online open access journal Critical Care, will help clinicians assess which interventions are likely to be best for their patients.

17 Jun 2007

Microinjection of live single cells

Specialized pulsed lasers have been used to inject individual cells with a variety of materials, but little is known about how this type of injection might affect living cells.

17 Jun 2007

Novel mutation associated with muscle identified

The study demonstrates that muscle weakness experienced by persons with a regulatory protein tropomyosin mutation is directly related to a mechanism by which the mutant tropomyosin modulates contractile speed and force-generation capacity.

17 Jun 2007

Better understanding of how the body fights off mucosal pathogens

In a finding that could have important implications for HIV vaccine research, new research at Weill Cornell Medical College illuminates the ways in which the body prevents its mucosal surfaces from being overwhelmed by bacteria.

17 Jun 2007

Focus on motor neurone disease

Motor neurone disease (MND), also known as amyotrophic lateral sclerosis, is a degenerative disease of unknown cause which causes patients to lose basic motor functions and has a devastating effect on them and their families.

17 Jun 2007

Synaptic dysfunction in Huntington's disease

Huntington's disease is a hereditary disorder that primarily affects the brain, leading to death within just over a decade.

17 Jun 2007

Researchers use 'genomic pathway' to predict Parkinson's

A new Mayo Clinic study provides strong evidence that the joint effects of common DNA variations in several genes that encode proteins within a well-defined biological pathway largely explain why some persons get Parkinson's disease while others don't, and even predict with great accuracy at what age people might develop their first symptoms.

17 Jun 2007

International map of rheumatoid arthritis

In the first international map of rheumatoid arthritis (RA), spanning Europe and beyond, significant national differences in RA severity can be directly traced to national economics, most notably health expenditure, as exposed by data from the QUEST-RA Study presented at EULAR 2007, the Annual Congress of the European League Against Rheumatism, Barcelona, Spain.

17 Jun 2007

Lupin announces FDA approval of Trandolapril tablets

Lupin Pharmaceuticals, Inc. announced that the U.S. Food and Drug Administration (FDA) has granted final approval for the Company's Abbreviated New Drug Application (ANDA) for Trandolapril Tablets, 1mg, 2mg and 4mg. Commercial shipments of Trandolapril tablets have commenced.

17 Jun 2007

Researchers identify potential role for retinoic acid in autoimmune and inflammatory diseases

An important finding, which could eventually lead to a new therapeutic approach for treating autoimmune and inflammatory diseases such as rheumatoid arthritis, colitis, psoriasis and others, was announced by researchers at the La Jolla Institute for Allergy & Immunology (LIAI).

17 Jun 2007

Many people fail to plan ahead when making dynamic decisions about their lives

More than half of the participants in experiments conducted at the University of York fail to plan ahead when making dynamic decisions about their lives, according to the findings of research funded by the Economic and Social Research Council that will have implications for policies on financial planning and pensions.

17 Jun 2007

Imagery rehearsal therapy helps insomniacs

In a study that insomniacs may find welcoming, imagery rehearsal therapy (IRT) has been shown to subjectively improve their ability to get a good night's sleep, according to research presented at SLEEP 2007, the 21st Annual Meeting of the Associated Professional Sleep Societies (APSS).

17 Jun 2007