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Calcium supplementation for improving bone mineral density in children

There's little question that most kids get too little calcium, but a new review of evidence casts doubt on the value of supplements and calcium-fortified foods to build stronger bones.

18 Apr 2006

Oral misoprostol for induction of labour

A popular anti-ulcer pill used around the world for inducing labor and preventing post-delivery bleeding appears to be as effective as more expensive drugs but still must be used with caution, according to an updated systematic review of studies.

18 Apr 2006

$Photorefractive keratectomy (PRK) versus laser-assisted in-situ keratomileusis (LASIK) for myopia$

Photorefractive keratectomy (PRK) versus laser-assisted in-situ keratomileusis (LASIK) for myopia

A new review of recent studies suggests two popular laser-assisted surgeries to correct nearsightedness are equally effective at restoring 20/20 vision six months to a year after the surgery.

18 Apr 2006

Short acting insulin analogues versus regular human insulin in patients with diabetes mellitus

Fast-acting artificial insulin drugs work just as well as regular human insulin, but it's unclear how they could affect the health of people with diabetes over the long run, according to a new review of recent studies.

18 Apr 2006

Breast implants not associated with an increased risk of cancer

Implants were associated with a decrease in breast cancer risk and an increased lung cancer risk, but these results likely reflect the lifestyles and smoking habits of the women in the study rather than an effect of the implants themselves, the authors conclude.

18 Apr 2006

Microarray analysis could lead to better understanding of mechanisms underlying the genetic propensity toward excessive drinking

The meta analysis, which examined more than 4.5 million data points on more than 100 microarrays from mouse models, also identified more than 1,300 functional groups, including signaling and transcription pathways, which may also play an important role in establishing a capacity for a "high level of alcohol consumption."

18 Apr 2006

Antibiotics for exacerbations of chronic obstructive pulmonary disease

People with chronic obstructive pulmonary disease often experience short term worsening and aggravation of their symptoms.

18 Apr 2006

Directly observed therapy for treating tuberculosis

Directly observed therapy (DOT) has no quantitatively important effect on cure rates or treatment completion in people receiving treatment for tuberculosis (TB).

18 Apr 2006

Buprenorphine is more effective than clonidine at helping people withdraw from opioids

It probably has similar effect as methadone, but withdrawal symptoms may resolve more quickly with buprenorphine.

18 Apr 2006

Compression stockings help prevent deep vein thrombosis

People wearing compression stockings on long-haul flights may have one tenth the risk of developing a deep vein thrombosis (DVT) compared to those who do not wear compression stockings. So concludes a systematic review of medical research to be published in The Cochrane Library.

18 Apr 2006

Inhaled corticosteroids ease asthma symptoms

Adults and children with asthma will breathe deeper and have better control over their asthma with inhaled corticosteroids than with the medicine cromolyn, according to a new review of recent studies comparing the two treatments.

18 Apr 2006

Prostate cancer research may be faster with prostate-specific antigen endpoints

A new study from Columbia University Medical Center researchers at NewYork-Presbyterian Hospital/Columbia, who are members of the Southwest Oncology Group (SWOG), suggests that certain changes in prostate-specific antigen (PSA) levels may serve as surrogate endpoints for prostate cancer survival.

18 Apr 2006

Researchers identify novel agent that protects neurons involved in Parkinson's disease from being destroyed by rotenone

Researchers at the University at Buffalo affiliated with the New York State Center of Excellence in Bioinformatics and Life Sciences have identified a novel agent that can protect neurons involved in Parkinson's disease from being destroyed by the pesticide rotenone.

18 Apr 2006