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Novel virus entry mechanism could lead to new drugs against poxviruses

Scientists working with Vaccinia virus, the smallpox vaccine, have discovered a novel mechanism that allows poxviruses to enter cells and cause infection.

13 Apr 2006

Researchers suggest drug could block metastasis or reduce pain for bone cancer patients

An international research team has identified what may be a critical molecule in the ability of tumours to metastasize -- or spread -- into bone.

13 Apr 2006

Cholesterol-lowering drug might not promote healthy hearts

Antioxidants, such as beta-carotene and Vitamin E, have been touted for their ability to protect against heart disease.

13 Apr 2006

Computer program lets people with Trigeminal neuralgia diagnose themselves

Trigeminal neuralgia, or TN, is a disorder affecting the areas of the face where the trigeminal nerve's branches are distributed, including the lips, eyes, nose, scalp, forehead, and upper and lower jaws.

13 Apr 2006

Dwindling time fuels happier outlook

Older adults' attention tilts toward positive feelings and associations, despite the time-limited future that comes with advancing age, concludes a Brandeis study in the journal Psychology and Aging.

13 Apr 2006

Proteomic mass spectrometry helps identify viruses

Scientists have used mass spectrometry for decades to determine the chemical composition of samples but rarely has it been used to identify viruses, and never in complex environmental samples.

13 Apr 2006

Ingredient in red chili pepper has cancer-fighting properties

The study found that capsaicin, the "hot" ingredient in red chili pepper, caused pancreatic cancer cells to die through a process called apoptosis.

13 Apr 2006

Loneliness is a unique predictor of age-related differences in systolic blood pressure

Loneliness is a major risk factor in increasing blood pressure in older Americans, and could increase the risk of death from stroke and heart disease, new research at the University of Chicago shows.

13 Apr 2006

Imaging of breast cancer diagnosed and treated with chemotherapy during pregnancy

Ultrasound provides a safe and accurate method of detecting breast cancers in pregnant women, as well as assessing response to chemotherapy, according to a study appearing in the April issue of Radiology.

13 Apr 2006

Hormone therapy associated with increased risk of breast cancer among black women

Previous research has suggested that the long-term use of female hormone therapy is associated with an increased risk of developing breast cancer, according to background information in the article.

13 Apr 2006

Angiotension-converting enzyme inhibitors may reduce cardiovascular risk

Angiotension-converting enzyme (ACE) inhibitors, medications commonly used to treat hypertension (high blood pressure), may reduce cardiovascular risk and the risk of death in patients with coronary artery disease, according to a new analysis of previously conducted clinical trials reported in the Archives of Internal Medicine.

13 Apr 2006

A hormone receptor with regulatory roles in food intake, fear response, and cardiovascular function may also be involved in breast cancer

The UC research team, led by Hassane Amlal, PhD, and Sulaiman Sheriff, PhD, report their laboratory findings on the hormone, neuropeptide Y, and its receptor in the April edition of the journal Cancer Research.

13 Apr 2006

Compounds derived from legume interaction with rhizobium bacteria may help cancer treatment

The ARC Centre of Excellence for Integrative Legume Research (CILR) has lodged a complete patent application for compounds to treat cancer.

13 Apr 2006

Simple screening process opens door to treating rare metabolic diseases such as Tay-Sachs, Fabry and Gaucher syndromes

Rare metabolic diseases such as Tay-Sachs, Fabry and Gaucher syndromes are caused by enzyme deficiencies and typically have crippling, even fatal, consequences starting at very early ages.

13 Apr 2006

First evidence that circulating endothelial microparticles lead to heart valve disease

Under normal physiological conditions, low levels of microparticles are continually being shed into the blood from the endothelium - the cells that line the inside of blood vessels and some organs -and appear to cause no problems.

13 Apr 2006

Researchers find genetic "signature" that accurately identifies colon cancer

Researchers at Jefferson Medical College in Philadelphia have uncovered a genetic "signature" that accurately identifies colon cancer--a key, they hope, to better understand how the cancer develops.

13 Apr 2006

Finding a cure for cancer would be worth about $50 trillion

Even a modest one percent reduction in mortality from cancer would be worth nearly $500 billion in social value, according to a new study by economists Kevin Murphy and Robert Topel of the University of Chicago Graduate School of Business.

13 Apr 2006

Analysis of different sweeteners and sweet substances

The most important factor in what kind of sweetener people prefer has little to do with how sweet it tastes. Rather, it has more to do with other tastes in the sweetener, such as bitterness or sourness, new research suggests.

13 Apr 2006

Trial of low-dose Isotretinoin for prevention of second primary tumors in head and neck cancer patients

Taking a vitamin A derivative called isotretinoin did not reduce the risk of second primary tumors or improve survival in patients with stage I or II head and neck squamous cell cancers (HNSCC), according to a study in the Journal of the National Cancer Institute.

13 Apr 2006

Soy intake may be associated with a small reduction in the risk of breast cancer

However, because of limitations and inconsistencies in the studies examined within the meta-analysis, the authors caution that evidence is not sufficient to recommend soy as a means of preventing breast cancer.

13 Apr 2006

Medical News

Novel virus entry mechanism could lead to new drugs against poxviruses

Researchers suggest drug could block metastasis or reduce pain for bone cancer patients

Cholesterol-lowering drug might not promote healthy hearts

Computer program lets people with Trigeminal neuralgia diagnose themselves

Dwindling time fuels happier outlook

Proteomic mass spectrometry helps identify viruses

Ingredient in red chili pepper has cancer-fighting properties

Loneliness is a unique predictor of age-related differences in systolic blood pressure

Imaging of breast cancer diagnosed and treated with chemotherapy during pregnancy

Hormone therapy associated with increased risk of breast cancer among black women

Angiotension-converting enzyme inhibitors may reduce cardiovascular risk

A hormone receptor with regulatory roles in food intake, fear response, and cardiovascular function may also be involved in breast cancer

Compounds derived from legume interaction with rhizobium bacteria may help cancer treatment

Simple screening process opens door to treating rare metabolic diseases such as Tay-Sachs, Fabry and Gaucher syndromes

First evidence that circulating endothelial microparticles lead to heart valve disease

Researchers find genetic "signature" that accurately identifies colon cancer

Finding a cure for cancer would be worth about $50 trillion

Analysis of different sweeteners and sweet substances

Trial of low-dose Isotretinoin for prevention of second primary tumors in head and neck cancer patients

Soy intake may be associated with a small reduction in the risk of breast cancer

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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