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Discovery provides an understanding of the mechanisms of oocyte death and a way to identify potential clinical treatments for infertility

An immature egg's internal nutrient supply is critical to its survival, an insight that offers a new route to understanding and treating infertility due to egg death, according to Duke University Medical Center researchers.

9 Oct 2005

Discovery of new features of a key quality-control mechanism in our cells

Mutations in genes are the basis of evolution, so we owe our existence to them. Most mutations are harmful, however, because they cause cells to build defective proteins. So cells have evolved quality control mechanisms that recognize and counteract genetic mistakes.

9 Oct 2005

Employment gap may be due, in part, to the "poverty trap"

Between 2003 and 2004 the employment gap widened between the number of working-age Americans with disabilities who are employed and those workers without disabilities, a new report on Capitol Hill shows.

9 Oct 2005

Fear of falling gait

The patient came into the doctor's office in a wheelchair, weighted down by a diagnosis of Parkinson's disease, taking medication for the disorder and insisting she was unable to stand or walk. Thirty minutes later, after jogging down the hallway, she strolled out the door.

9 Oct 2005

Long-term use of NSAIDs cuts the risk for oral cancer in smokers by half but increases risk of cardiovascular problems

An analysis of 20 years of data on the health of over 900 adults has found that long-term use of traditional nonsteroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen and naproxen, cuts the risk for oral cancer in smokers by half.

9 Oct 2005

Patients in level I trauma centers were nearly 20 percent less likely to die than those in level II centers

Patients who are taken to a level 2 trauma center after suffering serious injury are significantly more likely to die than comparable patients treated at a major level 1 trauma center, according to researchers at the Keck School of Medicine of the University of Southern California.

9 Oct 2005

SUVs should carry health warnings

Sports utility vehicles (SUVs) should carry health warnings to raise awareness of the increased risk to pedestrians compared with ordinary cars, argue researchers in this week's British Medical Journal.

9 Oct 2005

Recommendation that physicians be a little more cautious in deciding against tPA treatment

Although use of the clot-dissolving drug tissue plasminogen activator (tPA) has revolutionized the treatment of acute stroke patients, many of those who could receive the drug do not because their initial symptoms appear mild or improve soon after they arrive at the hospital.

9 Oct 2005

Melanoma patients with a positive family history and/or dysplastic nevi were found to be at higher risk for multiple primary melanomas

Memorial Sloan-Kettering Cancer Center (MSKCC) researchers have found that melanoma patients with a family history of melanoma and/or dysplastic nevi (abnormal moles) are at high risk of developing multiple primary melanomas (MPM). Researchers recommend more intensive follow up for these high-risk patients.

9 Oct 2005

20 percent of people with chronic hepatitis C who receive a liver transplant will develop advanced cirrhosis

A new study from the University of North Carolina at Chapel Hill School of Medicine may have found a way to identify those at greatest risk, thereby allowing doctors to decide who should receive treatment that could save the transplanted organ. The new findings appear in the October issue of the journal Liver Transplantation.

9 Oct 2005

Site in the brain that controls language in right-handed people shifts with aging

...a discovery that might offer hope in the treatment of speech problems resulting from traumatic brain injury or stroke.

9 Oct 2005

New report identifies over 40 infectious agents that pose significant human health problems in the United States or abroad

Vaccines have helped eradicate and tame some of history's worst infectious diseases, but there are many more diseases out there that vaccines can help overcome. The challenges society needs to confront to unlock the future promise of vaccines against the plagues of the 21st century are the focus of a new report by the American Academy of Microbiology.

9 Oct 2005

Specific gene on chromosome 15 regulates inflammation

A team of international researchers has discovered that a specific gene on chromosome 15 regulates inflammation, a finding with implications for a wide range of disorders, including cancer, cardiovascular disease, diabetes, obesity, Alzheimer's, and infections. The findings are published in the October 9 online issue of Nature Genetics.

9 Oct 2005

Britain's Naional Heath Service is being taken over by big business

Britain's Naional Heath Service is being taken over by big business so that money that could go towards clinical care is diverted to corporations and their shareholders, warn two senior doctors in this week's British Medical Journal.

9 Oct 2005

Recent shelving of a flagship PFI venture in West London may herald the end for the PFI healthcare experiment in the UK

Government enthusiasm for the Private Finance Initiative (PFI) in the health service - private sector investment in hospital building projects - may be dropping because of its high cost, says an editorial in this week's British Medical Journal.

9 Oct 2005

Osmolyte findings could have implications for the study of Alzheimer's disease, cystic fibrosis, kidney disease

Researchers at the University of Texas Medical Branch at Galveston (UTMB) have developed a new way to predict the ability of certain small molecules to protect proteins in the cells of a wide variety of organisms living in extreme environments.

9 Oct 2005

Gene variation may play fundamental role in the development and spread of cancer in the body

New research shows that a small gene variation that increases the risk of inherited cancer can also arise during the development of spontaneous, or non-inherited, tumors.

9 Oct 2005

RPL26 and nucleolin play critical roles in controlling the production of p53

Investigators at St. Jude Children's Research Hospital have discovered a previously unrecognized mechanism that controls a key protein linked to the cell's response to stress - a finding that holds promise for new ways to enhance cancer therapies or protect cells from dying after exposure to damaging chemicals or radiation.

9 Oct 2005

Scientists genetically modify male mosquitoes to express a glowing protein in their gonads - may help control the mosquito population

By providing a way to quickly sex mosquitoes, the advance paves the way for pooling large numbers of sterile males which could be used to control the mosquito population.

9 Oct 2005

New data demonstrates how CA4P has anti-tumor and anti-angiogenic activity

Anti-angiogenic agents have been successful in the clinic for blocking the growth of solid tumors. However, these agents used in combination with chemotherapy have improved the survival of patients with cancers by only several months.

9 Oct 2005

Medical News

Discovery provides an understanding of the mechanisms of oocyte death and a way to identify potential clinical treatments for infertility

Discovery of new features of a key quality-control mechanism in our cells

Employment gap may be due, in part, to the "poverty trap"

Fear of falling gait

Long-term use of NSAIDs cuts the risk for oral cancer in smokers by half but increases risk of cardiovascular problems

Patients in level I trauma centers were nearly 20 percent less likely to die than those in level II centers

SUVs should carry health warnings

Recommendation that physicians be a little more cautious in deciding against tPA treatment

Melanoma patients with a positive family history and/or dysplastic nevi were found to be at higher risk for multiple primary melanomas

20 percent of people with chronic hepatitis C who receive a liver transplant will develop advanced cirrhosis

Site in the brain that controls language in right-handed people shifts with aging

New report identifies over 40 infectious agents that pose significant human health problems in the United States or abroad

Specific gene on chromosome 15 regulates inflammation

Britain's Naional Heath Service is being taken over by big business

Recent shelving of a flagship PFI venture in West London may herald the end for the PFI healthcare experiment in the UK

Osmolyte findings could have implications for the study of Alzheimer's disease, cystic fibrosis, kidney disease

Gene variation may play fundamental role in the development and spread of cancer in the body

RPL26 and nucleolin play critical roles in controlling the production of p53

Scientists genetically modify male mosquitoes to express a glowing protein in their gonads - may help control the mosquito population

New data demonstrates how CA4P has anti-tumor and anti-angiogenic activity

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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