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New flu vaccine takes weeks to mass produce

Using cell-based methods researchers have developed a commercially viable method for mass producing effective vaccines against potential pandemic influenza strains in weeks instead of the months required for traditional egg-based vaccines.

17 Feb 2006

Farnesyltransferase inhibitor may improve progeria

UCLA researchers found that an experimental cancer drug improves the signs of progeria in a mouse model. Progeria is a rare genetic disease causing accelerated aging and cardiovascular disease in children. The new UCLA findings help to define a new strategy for treating children with progeria.

17 Feb 2006

Older asthmatics have increased cancer risk

New research shows that older adults with asthma are at an increased risk for developing cancer, and adults with asthma are twice as likely to suffer from heart disease and other chronic health conditions.

17 Feb 2006

Scientists map brain area that may help find human brain stem cells

A study led by a Johns Hopkins neurosurgeon has provided the first comprehensive map of a part of the adult human brain containing astrocytes, cells known to produce growth factors critical to the regeneration of damaged neural tissue and that potentially serve as brain stem cells.

17 Feb 2006

Adjuvant hormonal therapy reduces contralateral breast cancer risk

The risk for a new cancer in the unaffected breast substantially increases in women diagnosed with unilateral, hereditary (non-BRCA) breast cancer, according to a new study.

17 Feb 2006

Study examines treatment to maintain blood pressure in those with disorder causing postural drops

Use of a medication called pyridostigmine alone or in combination with low-dose midodrine appears to improve standing blood pressure in patients with orthostatic hypotension, a fall in blood pressure associated with postural changes and standing

17 Feb 2006

Genetics of human muscular dystrophy

Various forms of human muscular dystrophy result from mutations in genes encoding proteins of the nuclear envelope. A new paper in the February 15th issue of G&D reveals how.

17 Feb 2006

Major Alzheimer's discovery

A team from the Faculty of Medicine at Universiti Laval and the research centre at CHUQ (Centre hospitalier universitaire de Quibec) has discovered a natural defence mechanism that the body deploys to combat nerve cell degeneration observed in persons with Alzheimer's disease (AD).

17 Feb 2006

Genome data may contain small but significant errors

Since the genome sequence of the bacterial pathogen Haemophilus influenzae was published in 1995, the genetic code of many other large, complex, medically, and commercially significant organisms including humans has also been elucidated

17 Feb 2006

Science is bypassing poor people

Applying science and technology to build a Pluto-bound spacecraft that travels more than 10 times faster -- 47,000 miles per hour -- than a speeding bullet is a great achievement. But can we apply technology to feed the 800 million hungry people in the world whose plight isn't improving in a modern world?

17 Feb 2006

Study takes in-depth look at fathering in families

A study published in the current issue of Family Process provides an in-depth look at fathering in families with young children and finds that the most involved fathers live outside traditional gendered roles.

17 Feb 2006

More physical activity does not lower risk of colon cancer

A prospective cohort study of 31,783 American women has found no significant association between levels of physical activity and colon cancer incidence.

17 Feb 2006

Boys are almost twice as likely as girls to burn themselves

Boys are almost twice as likely as girls to burn themselves and children under three face particular risks, according to research published in the February issue of Journal of Clinical Nursing.

17 Feb 2006

Protein level predicts who will develop graft vs. host disease after marrow transplant

Researchers could determine one week after a bone marrow transplant which patients were likely to develop a serious and deadly complication, making them candidates for preventive treatment before any symptoms occur.

17 Feb 2006

Elastin fragments drive emphysema

Pulmonary emphysema is caused primarily by cigarette smoking, and the underlying cellular mechanisms are thought to involve smoke-induced activation of tissue degrading enzymes known as proteases.

16 Feb 2006

Research suggests that a common mechanism may underlie a variety of protein folding diseases

Misfolded and damaged proteins are common to all human neurodegenerative diseases. Clumps of these aggregated proteins destroy neurons within the brain and cause disease.

16 Feb 2006

Global warming may be reducing respiratory illnesses

Rising global temperatures over the past two decades may be responsible for a shortened season of a serious respiratory illness in the United Kingdom, according to an article in the March 1 issue of Clinical Infectious Diseases.

16 Feb 2006

Macrophage signaling may affect hormone resistance in prostate tumors

Interaction between prostate cancer cells and immune cells called macrophages may be a source of inflammatory signals capable of impacting the effectiveness of androgen antagonists, the most common and effective treatment for prostate cancer, according to a new study by researchers at the University of California, San Diego (UCSD) School of Medicine.

16 Feb 2006

Purdue biologists visualize protein interaction that may initiate viral infection

Biologists at Purdue University have taken a "snapshot" of a Velcro-like protein on a cell's surface just after it attached to the dengue virus, a linkup thought to initiate the early stages of infection.

16 Feb 2006

Advancing knowledge of diet-gene interactions

Josi Ordovas, PhD, director of the Nutrition and Genomics Laboratory at the Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University joined more than eighty other leading researchers in the fields of nutrition and genetics to co-author a report outlining their strategy for maximizing the impact of nutrigenomics research on global poverty and health.

16 Feb 2006