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New research will play a major role in improving the future of breast cancer treatment

Cancer specialists at University of East Anglia have discovered that several 'ADAMTS' genes are turned off in breast cancer compared to normal breast tissue, while others are switched on. These genes could be targets for the development of 'smart' drugs tailored to treat individual patients' tumours.

19 Sep 2005

Molecular pathway in mice that makes prostate cells vulnerable to cancer-causing oxygen damage

Scientists from Maryland and New Jersey have identified a molecular pathway in mice that makes prostate cells vulnerable to cancer-causing oxygen damage.

19 Sep 2005

Natural daily body rhythms may influence the effectiveness of spinal-epidural pain medication

The study found that women who had day labor got longer pain relief than women with night labor with the same amount of labor pain medicine.

19 Sep 2005

First-of-its-kind test on a microchip array will help diagnose retinitis pigmentosa

Rapid genetic testing for eye disease is becoming a reality, thanks to a technology developed at the University of Michigan Kellogg Eye Center.

19 Sep 2005

Study suggests chronic infections may create autoimmune response

New research finds the human immune system has foregone evolutionary changes that would allow it to produce better antibodies in less time because the improved antibodies would be far more likely to attack the body's own tissues.

19 Sep 2005

Methoxychlor (MXC), a common insect pesticide may lead to reduced fertility in women

Methoxychlor (MXC), a common insect pesticide used on food crops, may interfere with proper development and function of the reproductive tract, leading to reduced fertility in women, researchers at Yale School of Medicine write in the August issue of Endocrinology.

19 Sep 2005

Making practical markets for vaccines

Two papers published on September 13 in PLoS Medicine raise concerns about whether world leaders are getting good advice on how best to fund the development and delivery of new vaccines.

19 Sep 2005

Drug AMD-3100 may help cancer patients who need stem cell transplants

A new drug may help cancer patients mobilize the cells necessary to restore their blood-forming system after high-dose chemotherapy, according to results from a clinical trial at the Kimmel Cancer Center at Thomas Jefferson University Hospital in Philadelphia and at other centers across the nation.

19 Sep 2005

46,000 crack cocaine users aged 15-44 in London

Researchers believe there could be 46,000 crack cocaine users aged 15-44 in London, suggesting one in every hundred young adult Londoners could be a user.

19 Sep 2005

Researchers selectively knock out memory associations connected with receiving cocaine

Addicts crave drugs and suffer relapse not just because of the alluring high of drugs, but also because they are compelled by the powerful, haunting memory associations with the environment surrounding their drug taking. Thus, treatments that could eliminate those memory associations could prove effective in treating addiction, researchers believe.

19 Sep 2005

Less-virulent strain of avian influenza virus can spread from poultry to humans

In findings with implications for pandemic influenza, a new study reports for the first time that a less-virulent strain of avian influenza virus can spread from poultry to humans. The research appears in the October 1 issue of The Journal of Infectious Diseases, now available online.

19 Sep 2005

In some poor countries, free life-saving HIV medicines are being given preferentially to patients

...who have never taken them before (so-called 'treatment-naive patients'), which could have disastrous consequences, says a team of researchers in Uganda.

19 Sep 2005

Women with atrial fibrillation face a higher risk of ischemic stroke than men

Women with atrial fibrillation who are not on anticoagulant therapy have a higher rate of ischemic stroke and face a higher absolute risk for stroke than do men with the condition, according to a joint study

19 Sep 2005

Manic depression linked to two chromosomal regions in the human genome

An international team of 53 researchers has offered the most convincing evidence so far linking bipolar disorder, also known as manic depression, to two chromosomal regions in the human genome. The finding gives scientists refined targets for further gene studies.

19 Sep 2005

Cost-cutting strategy employed by HMOs for 15 years is simply not working

With rising concern over the cost of the new Medicare prescription drug benefit program – going into effect January, 2006 and estimated to cost $593 billion over the next decade – a new UCSF study reveals that a key cost-cutting strategy employed by HMOs for 15 years is simply not working.

19 Sep 2005

Impact of prevention strategies and improvements in stroke healthcare

Coinciding with National Stroke Week in Australia (19 - 25 September 2005) is the release of results from two recent stroke studies from the George Institute for International Health that investigate both the causative factors as well as a little studied outcome of stroke, that of depression.

19 Sep 2005

MRC study to monitor Pentosan Polysulphate as a treatment for Creutzfeldt-Jakob disease receives approval

The plans for a monitoring study on patients being treated with Pentosan Polysulphate (PPS) for CJD and variant CJD have received a favourable opinion from the Eastern Multi-Centre Research Ethics Committee. This follows a provisional opinion from the committee in August.

19 Sep 2005

Lowering blood sugar levels could reduce the risk of coronary heart disease

Lowering blood sugar levels could reduce the risk of coronary heart disease in both diabetics and non-diabetics, according to researchers at the Johns Hopkins Bloomberg School of Public Health and other institutions.

19 Sep 2005

Does surgery induce angiogenesis in dormant breast cancer?

Analysis of breast-cancer relapse patterns from two independent databases provides indirect evidence for the theory that surgery to remove the primary tumor may initiate formation of a new blood supply (angiogenesis) in formerly dormant metastases, accounting for a pattern of early relapse in younger women.

12 Sep 2005

Bariatric surgery is a safe option for treating obese patients who have coronary artery disease

The findings are important because coronary artery disease patients can see a significant benefit with a successful procedure. The resulting weight loss is also followed by an improvement in blood pressure, cholesterol, blood sugar and sleep apnea, all factors linked to coronary artery disease.

12 Sep 2005

Medical News

New research will play a major role in improving the future of breast cancer treatment

Molecular pathway in mice that makes prostate cells vulnerable to cancer-causing oxygen damage

Natural daily body rhythms may influence the effectiveness of spinal-epidural pain medication

First-of-its-kind test on a microchip array will help diagnose retinitis pigmentosa

Study suggests chronic infections may create autoimmune response

Methoxychlor (MXC), a common insect pesticide may lead to reduced fertility in women

Making practical markets for vaccines

Drug AMD-3100 may help cancer patients who need stem cell transplants

46,000 crack cocaine users aged 15-44 in London

Researchers selectively knock out memory associations connected with receiving cocaine

Less-virulent strain of avian influenza virus can spread from poultry to humans

In some poor countries, free life-saving HIV medicines are being given preferentially to patients

Women with atrial fibrillation face a higher risk of ischemic stroke than men

Manic depression linked to two chromosomal regions in the human genome

Cost-cutting strategy employed by HMOs for 15 years is simply not working

Impact of prevention strategies and improvements in stroke healthcare

MRC study to monitor Pentosan Polysulphate as a treatment for Creutzfeldt-Jakob disease receives approval

Lowering blood sugar levels could reduce the risk of coronary heart disease

Does surgery induce angiogenesis in dormant breast cancer?

Bariatric surgery is a safe option for treating obese patients who have coronary artery disease

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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