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Abnormal leakage of lymph fluid from the ruptured lymphatic vessels stimulates the accumulation of fat

Leaky lymphatic vessels are the leading cause of the adult onset obesity observed in a laboratory model developed by investigators at St. Jude Children's Research Hospital.

26 Sep 2005

Scientists eventually may be able to determine the structure of proteins from their genomic sequences

Computers can predict the detailed structure of small proteins nearly as well as experimental methods, at least some of the time, according to new studies by Howard Hughes Medical Institute researchers.

26 Sep 2005

Smoking may increase the risk of developing diabetes

The surprising finding emerged when researchers examined the relationship between smoking and diabetes among participants in a major national study, the Insulin Resistance Atherosclerosis Study (IRAS).

26 Sep 2005

Possible molecular origin of at least nine human diseases of nervous system degeneration

These neurodegenerative diseases, including Huntington's disease, share an abnormal deposit of proteins inside nerve cells. This deposition of protein results from a kind of genetic stutter within the cell's nucleus asking for multiple copies of the amino acid glutamine, a building block of protein structure.

26 Sep 2005

"Designer" rats help show how declining estrogen after menopause can affect hypertension

Scientists at Wake Forest University School of Medicine have created a better research rat – the first to enable them to study how declining estrogen after menopause can affect hypertension, heart failure and kidney damage.

26 Sep 2005

Stopping UK BCG vaccination well justified

From autumn 2005, the long running routine programme to vaccinate school children against tuberculosis with BCG vaccine will stop. This decision brings the UK into line with much of the rest of the world and is well justified, writes Professor Paul Fine in the British Medical Journal (BMJ).

26 Sep 2005

British Medical Journal publishes euthanasia opinions

Next month's debate in the House of Lords could begin the process of changing the law on euthanasia and physician assisted suicide. To help doctors decide where they stand, the British Medical Journal has published a range of opinions.

26 Sep 2005

Notch1 and Jagged1 genes are likely markers indicating a patient's probable aggressive breast cancer

In a new study, scientists at The Hospital for Sick Children and Princess Margaret Hospital have shown that two genes called Notch1 and Jagged1 are linked to more aggressive breast cancers and that patients are less likely to survive the disease when these two genes are highly expressed.

26 Sep 2005

New approach to treating brain aneurysm combining the use of intracranial stents and coil embolization

A fender-bender may have saved Douglas Collins' life. A CT scan following the accident discovered Collins, 64, had a brain aneurysm, a weakness in the arterial wall that if ruptured could cause a stroke or death. It was not caused by the accident, but likely could have been a ticking time bomb present for years. The aneurysm was large and previously thought to require open surgery and a lengthy recovery.

26 Sep 2005

New nutritional challenges in HIV/AIDS care have emerged

Nutritional therapy for HIV-infected patients is shifting focus. Drug treatments designed to combat the HIV virus have improved, decreasing some nutritional problems, while bringing others to light.

26 Sep 2005

First-of-its kind atlas of the folds of the cerebral cortex

Neuroscientists at Washington University School of Medicine in St. Louis have assembled a first-of-its kind atlas of the folds of the cerebral cortex, the wrinkled surface layer of the brain credited with many of the higher cognitive functions that make us human.

26 Sep 2005

Research highlights the role of viral sequence analysis in improving our overall understanding of hepatitis A cases in the U.S.

Novel use of genetic testing methods helped public health officials control and limit the further spread of four outbreaks of foodborne hepatitis A virus in 2003 related to the consumption of green onions, according to a detailed analysis published in the October 15 issue of The Journal of Infectious Diseases, now available online.

26 Sep 2005

Questionnaire helps identify women who have inherited genetic mutations that increase their risk for breast or ovarian cancer

A simplified way for patients to report and update their family medical histories could help identify women who have inherited genetic mutations that increase their risk for breast or ovarian cancer.

26 Sep 2005

No significant differences among different ethnic groups for breast cancer related to hormone replacement therapy

The study, published online September 16, 2005 in the International Journal of Cancer, the official journal of the International Union Against Cancer (UICC), did find that leaner women taking hormone replacement therapy had a relatively greater increase in breast cancer risks than heavier women.

26 Sep 2005

Five-year-olds are able to grasp numeric abstractions and arithmetic concepts

Psychologists at Harvard University have found that five-year-olds are able to grasp numeric abstractions and arithmetic concepts even without the formal education or language to express this knowledge in words.

26 Sep 2005

Halloween often lost on young kids

Halloween may seem like so much harmless fun, a time when adults enjoy laughing in the face of death, and implore their young children to do the same. According to a Penn State researcher, however, the humor of tombstones, monsters and other scary elements is often lost on kids at the ripe age of 6 or 7--many of whom don't find the holiday the least bit funny.

26 Sep 2005

Two recent studies may help clinicians and researchers better predict and understand dementia of the Alzheimer's type

Both studies appear in the September issue of Neuropsychology, which is published by the American Psychological Association (APA). Psychologists focus on early detection in part because current medications are useful only when given very early in the course of the disease.

26 Sep 2005

Warning: Popularity may be hazardous to pre-teens' health

According to a study in the October issue of the Journal of Adolescent Health, popular students in 16 Southern California middle schools were more likely to become smokers than their less popular peers.

26 Sep 2005

Link between ambient air pollution and acute myocardial infarction, or heart attack

An article published in the Journal of Thrombosis and Haemostasis looks specifically at airborne particulate matter resulting mainly from the combustion of fuel, including coal and also from forest fires.

26 Sep 2005

Polymorphisms in a receptor called CD32 influence the response to antibody therapy in cancer

In a paper appearing online in advance of print publication of the October 1 issue of the Journal of Clinical Investigation, Adam Boruchov and colleagues from Memorial Sloan Kettering Cancer Center dissect the contributions of CD32 isoforms in human dendritic cell (DC) activation and function.

26 Sep 2005

Medical News

Abnormal leakage of lymph fluid from the ruptured lymphatic vessels stimulates the accumulation of fat

Scientists eventually may be able to determine the structure of proteins from their genomic sequences

Smoking may increase the risk of developing diabetes

Possible molecular origin of at least nine human diseases of nervous system degeneration

"Designer" rats help show how declining estrogen after menopause can affect hypertension

Stopping UK BCG vaccination well justified

British Medical Journal publishes euthanasia opinions

Notch1 and Jagged1 genes are likely markers indicating a patient's probable aggressive breast cancer

New approach to treating brain aneurysm combining the use of intracranial stents and coil embolization

New nutritional challenges in HIV/AIDS care have emerged

First-of-its kind atlas of the folds of the cerebral cortex

Research highlights the role of viral sequence analysis in improving our overall understanding of hepatitis A cases in the U.S.

Questionnaire helps identify women who have inherited genetic mutations that increase their risk for breast or ovarian cancer

No significant differences among different ethnic groups for breast cancer related to hormone replacement therapy

Five-year-olds are able to grasp numeric abstractions and arithmetic concepts

Halloween often lost on young kids

Two recent studies may help clinicians and researchers better predict and understand dementia of the Alzheimer's type

Warning: Popularity may be hazardous to pre-teens' health

Link between ambient air pollution and acute myocardial infarction, or heart attack

Polymorphisms in a receptor called CD32 influence the response to antibody therapy in cancer

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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