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First large-scale whole genome map of genetic variability associated with Parkinson's disease

Mayo Clinic researchers in collaboration with scientists at Perlegen Sciences, Inc. and funded by the Michael J. Fox Foundation for Parkinson's Research have produced the first large-scale whole genome map of genetic variability associated with Parkinson's disease.

19 Sep 2005

Stress and breast cancer link

High levels of daily stress appear to result in a lower risk of developing breast cancer for the first time, says a study in the British Medical Journal.

19 Sep 2005

Acute-leukemia sign may signal need for different therapy

A type of chromosome change that was thought to predict a good response to treatment in patients with acute myeloid leukemia (AML) might actually signal the need for a different therapy to achieve the best outcome.

19 Sep 2005

Compounds found in broccoli, cauliflower, and watercress block lung cancer progression

A family of compounds found in cruciferous vegetables, such as broccoli, cauliflower, and watercress, blocked lung cancer progression in both animal studies and in tests with human lung cancer cells, report researchers from Georgetown University Medical Center and the Institute for Cancer Prevention.

19 Sep 2005

Researchers detail molecular images of a piece of the spike-shaped protein that the SARS virus uses initiate the first stages of infection

Researchers have determined the first detailed molecular images of a piece of the spike-shaped protein that the SARS virus uses to grab host cells and initiate the first stages of infection.

19 Sep 2005

People who exercise regularly experience 25% less muscle and joint pain in their old age

Research published in Arthritis Research & Therapy reveals that people who regularly participate in brisk aerobic exercise, such as running, experience less pain than non-runners even though they are more likely to suffer from pain from injuries.

19 Sep 2005

Human fat cells produce a protein that is linked to both inflammation and an increased risk of heart disease and stroke

Researchers at The University of Texas M. D. Anderson Cancer Center and The University of Texas Health Science Center at Houston have found that human fat cells produce a protein that is linked to both inflammation and an increased risk of heart disease and stroke.

19 Sep 2005

Tarceva should be tested as front-line therapy for older lung cancer patients

The tyrosine kinase inhibitor erlotinib (Tarceva) showed encouraging activity with relatively tolerable side effects in elderly, previously untreated patients with advanced non-small cell lung cancer (NSCLC), reports a team led by investigators from Dana-Farber Cancer Institute in Boston.

19 Sep 2005

Scientists have discovered a new and potent anti-cancer compound in beans

Scientists have discovered a new and potent anti-cancer compound in everyday food. The collaborative study led by UCL (University College London) shows that the compound - inositol pentakisphosphate - found in beans, nuts and cereals inhibits a key enzyme (phosphoinositide 3-kinase) involved in tumour growth.

19 Sep 2005

New research will play a major role in improving the future of breast cancer treatment

Cancer specialists at University of East Anglia have discovered that several 'ADAMTS' genes are turned off in breast cancer compared to normal breast tissue, while others are switched on. These genes could be targets for the development of 'smart' drugs tailored to treat individual patients' tumours.

19 Sep 2005

Molecular pathway in mice that makes prostate cells vulnerable to cancer-causing oxygen damage

Scientists from Maryland and New Jersey have identified a molecular pathway in mice that makes prostate cells vulnerable to cancer-causing oxygen damage.

19 Sep 2005

Natural daily body rhythms may influence the effectiveness of spinal-epidural pain medication

The study found that women who had day labor got longer pain relief than women with night labor with the same amount of labor pain medicine.

19 Sep 2005

First-of-its-kind test on a microchip array will help diagnose retinitis pigmentosa

Rapid genetic testing for eye disease is becoming a reality, thanks to a technology developed at the University of Michigan Kellogg Eye Center.

19 Sep 2005

Study suggests chronic infections may create autoimmune response

New research finds the human immune system has foregone evolutionary changes that would allow it to produce better antibodies in less time because the improved antibodies would be far more likely to attack the body's own tissues.

19 Sep 2005

Methoxychlor (MXC), a common insect pesticide may lead to reduced fertility in women

Methoxychlor (MXC), a common insect pesticide used on food crops, may interfere with proper development and function of the reproductive tract, leading to reduced fertility in women, researchers at Yale School of Medicine write in the August issue of Endocrinology.

19 Sep 2005

Making practical markets for vaccines

Two papers published on September 13 in PLoS Medicine raise concerns about whether world leaders are getting good advice on how best to fund the development and delivery of new vaccines.

19 Sep 2005

Drug AMD-3100 may help cancer patients who need stem cell transplants

A new drug may help cancer patients mobilize the cells necessary to restore their blood-forming system after high-dose chemotherapy, according to results from a clinical trial at the Kimmel Cancer Center at Thomas Jefferson University Hospital in Philadelphia and at other centers across the nation.

19 Sep 2005

46,000 crack cocaine users aged 15-44 in London

Researchers believe there could be 46,000 crack cocaine users aged 15-44 in London, suggesting one in every hundred young adult Londoners could be a user.

19 Sep 2005

Researchers selectively knock out memory associations connected with receiving cocaine

Addicts crave drugs and suffer relapse not just because of the alluring high of drugs, but also because they are compelled by the powerful, haunting memory associations with the environment surrounding their drug taking. Thus, treatments that could eliminate those memory associations could prove effective in treating addiction, researchers believe.

19 Sep 2005

Less-virulent strain of avian influenza virus can spread from poultry to humans

In findings with implications for pandemic influenza, a new study reports for the first time that a less-virulent strain of avian influenza virus can spread from poultry to humans. The research appears in the October 1 issue of The Journal of Infectious Diseases, now available online.

19 Sep 2005

Medical News

First large-scale whole genome map of genetic variability associated with Parkinson's disease

Stress and breast cancer link

Acute-leukemia sign may signal need for different therapy

Compounds found in broccoli, cauliflower, and watercress block lung cancer progression

Researchers detail molecular images of a piece of the spike-shaped protein that the SARS virus uses initiate the first stages of infection

People who exercise regularly experience 25% less muscle and joint pain in their old age

Human fat cells produce a protein that is linked to both inflammation and an increased risk of heart disease and stroke

Tarceva should be tested as front-line therapy for older lung cancer patients

Scientists have discovered a new and potent anti-cancer compound in beans

New research will play a major role in improving the future of breast cancer treatment

Molecular pathway in mice that makes prostate cells vulnerable to cancer-causing oxygen damage

Natural daily body rhythms may influence the effectiveness of spinal-epidural pain medication

First-of-its-kind test on a microchip array will help diagnose retinitis pigmentosa

Study suggests chronic infections may create autoimmune response

Methoxychlor (MXC), a common insect pesticide may lead to reduced fertility in women

Making practical markets for vaccines

Drug AMD-3100 may help cancer patients who need stem cell transplants

46,000 crack cocaine users aged 15-44 in London

Researchers selectively knock out memory associations connected with receiving cocaine

Less-virulent strain of avian influenza virus can spread from poultry to humans

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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